Zobrazeno 1 - 10
of 221
pro vyhledávání: '"H, Bunzendahl"'
Publikováno v:
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress. 115
The analysis of amino acids in perfusion effluents in experimental liver transplantation is a valid parameter of organ viability at organ harvest. Depletion of Kupffer cells with gadolinium chloride (GdCl3) in donor animals prevents primary nonfuncti
[Preparing the donor with glycine improves survival after liver transplantation in the animal model]
Publikováno v:
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress. 115
The etiology of primary graft non-function has been linked to storage and reperfusion injury. Recently, graft manipulation during harvest was shown to aggravate reperfusion injury in livers effecting outcome after transplantation detrimentally. Since
Autor:
H. Bunzendahl, T. G. Lehmann
Publikováno v:
Zurück in die Zukunft ISBN: 9783540200024
Die Lebertransplantation in der Ratte ist ein standardisiertes Modell zur Untersuchung grundlagenwissenschaftlicher Fragestellungen zu Ischamie/Reperfusionsschaden und der Immunologie der Rejektion. Verschiedene Studien konnten eindeutig die Notwendi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee5048976d06324ea5a46f41248416b3
https://doi.org/10.1007/978-3-642-55611-1_355
https://doi.org/10.1007/978-3-642-55611-1_355
Autor:
T G, Lehmann, M D, Wheeler, R F, Schwabe, H D, Connor, R, Schoonhoven, H, Bunzendahl, D A, Brenner, R, Jude Samulski, Z, Zhong, R G, Thurman
Publikováno v:
Hepatology (Baltimore, Md.). 32(6)
Oxygen-derived free radicals play a central role in reperfusion injury after organ transplantation, and fatty livers are particularly susceptible. Endogenous radical scavengers such as superoxide dismutase (SOD) degrade these radicals; however, SOD i
Publikováno v:
Transplantation. 69(6)
Oxygen-derived free radicals play a central role in pathomechanisms of reperfusion injury after organ transplantation. Endogenous radical scavenger systems such as superoxide dismutase (SOD) degrade toxic radicals; however, SOD is degraded rapidly wh
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(1)
Kupffer cell-dependent injury in livers gently manipulated during harvest develops upon transplantation; however, underlying mechanisms remain unknown. Thus, the purpose of this study was to identify factors involved in mechanisms of injury. Livers f
Publikováno v:
Transplantation. 67(10)
In a recent study, disturbances of hepatic microcirculation at harvesting caused by in situ organ manipulation dramatically reduced survival after a liver transplant. Because hepatic innervation is involved in the regulation of liver hemodynamics, th
Publikováno v:
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress. 115
Kupffer cell-dependent reperfusion injury occurs to the liver following transplantation, most often in fatty livers which fail most frequently due to primary nonfunction. Failure was largely blocked with Carolina rinse solution, which contains glycin
Publikováno v:
Transplantation. 65(8)
The etiology of primary graft nonfunction and dysfunction is unknown but most likely involves Kupffer cell-dependent reperfusion injury. However, the donor operation and surgical technique may also have an effect on the outcome after transplantation.