Zobrazeno 1 - 10
of 6 362
pro vyhledávání: '"H, BERGER"'
Autor:
Amanda K. Riley, Michael Grant, Aidan Snell, Elizabeth Cromwell, Athea Vichas, Sitapriya Moorthi, Callie Rominger, Shrikar P. Modukuri, Anatoly Urisman, Pau Castel, Lixin Wan, Alice H. Berger
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110499- (2024)
Summary: RIT1 is a rare and understudied oncogene in lung cancer. Despite structural similarity to other RAS GTPase proteins such as KRAS, oncogenic RIT1 activity does not appear to be tightly regulated by nucleotide exchange or hydrolysis. Instead,
Externí odkaz:
https://doaj.org/article/80139380a31c425ebc93373b402148ab
Autor:
Hannah W. Despres, Margaret G. Mills, Madaline M. Schmidt, Jolene Gov, Yael Perez, Mars Jindrich, Allison M. L. Crawford, Warren T. Kohl, Elias Rosenblatt, Hannah C. Kubinski, Benjamin C. Simmons, Miles C. Nippes, Anne J. Goldenberg, Kristina E. Murtha, Samantha Nicoloro, Mia J. Harris, Avery C. Feeley, Taylor K. Gelinas, Maeve K. Cronin, Robert S. Frederick, Matthew Thomas, Meaghan E. Johnson, James Murphy, Elle B. Lenzini, Peter A. Carr, Danielle H. Berger, Soham P. Mehta, Christopher J. Floreani, Amelia C. Koval, Aleah L. Young, Jess H. Fish, Jack Wallace, Ella Chaney, Grace Ushay, Rebecca S. Ross, Erin M. Vostal, Maya C. Thisner, Kyliegh E. Gonet, Owen C. Deane, Kari R. Pelletiere, Vegas C. Rockafeller, Madeline Waterman, Tyler W. Barry, Catriona C. Goering, Sarah D. Shipman, Allie C. Shiers, Claire E. Reilly, Alanna M. Duff, Sarah L. Madruga, David J. Shirley, Keith R. Jerome, Ailyn C. Pérez-Osorio, Alexander L. Greninger, Nick Fortin, Brittany A. Mosher, Emily A. Bruce
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Previous studies have documented natural infections of SARS-CoV-2 in various domestic and wild animals. More recently, studies have been published noting the susceptibility of members of the Cervidae family, and infections in both wild and c
Externí odkaz:
https://doaj.org/article/859cc0d2dbd541ed9828efe688877a5a
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Alternative RNA splicing is widely dysregulated in cancers including lung adenocarcinoma, where aberrant splicing events are frequently caused by somatic splice site mutations or somatic mutations of splicing factor genes. However
Externí odkaz:
https://doaj.org/article/37b055328bd444adb4bdac801f188e35
Autor:
Siobhan O’Brien, Alice H. Berger
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 10, Pp 100618- (2023)
Publishing in Science, Girish and colleagues achieve chromosome-level genome editing to reveal a requirement for aneuploidy in breast and melanoma cancers. Authors developed and leveraged ReDACT (restoring disomy in aneuploid cells using CRISPR targe
Externí odkaz:
https://doaj.org/article/a5297b29c490486a9eea025f7902fe81
Publikováno v:
Wind Energy Science, Vol 7, Pp 1441-1453 (2022)
This paper presents a method for estimating offshore extractable wind power at hub height using Sentinel-1 synthetic aperture radar (SAR) data and machine learning. The method was tested in two areas off the Dutch coast, where measurements from Doppl
Externí odkaz:
https://doaj.org/article/6663700a54a142fe92d40a2a4ab16714
Autor:
Roisin MacDermott, Ferco H. Berger, Andrea Phillips, Jason A. Robins, Michael E. O’Keeffe, Rawan Abu Mughli, David B. MacLean, Grace Liu, Heather Heipel, Avery B. Nathens, Sadia Raheez Qamar
Publikováno v:
Diagnostics, Vol 14, Iss 3, p 276 (2024)
Trauma is the leading non-obstetric cause of maternal and fetal mortality and affects an estimated 5–7% of all pregnancies. Pregnant women, thankfully, are a small subset of patients presenting in the trauma bay, but they do have distinctive physio
Externí odkaz:
https://doaj.org/article/58410a376ad94200aad57c2a90f58f4c
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Autor:
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
RIT1 mutations are mutually exclusive with other lung cancer drivers and lack targeted therapies. Here the authors examine genetic dependencies of mutant RIT1 with genome-wide CRISPR screens, revealing synergy between RIT1 and YAP1, and increased sen
Externí odkaz:
https://doaj.org/article/06e749d7f425413a87006cc1366f2c04
Autor:
G. Gatti, D. Gosálbez-Martínez, S. Roth, M. Fanciulli, M. Zacchigna, M. Kalläne, K. Rossnagel, C. Jozwiak, A. Bostwick, E. Rotenberg, A. Magrez, H. Berger, I. Vobornik, J. Fujii, O. V. Yazyev, M. Grioni, A. Crepaldi
Publikováno v:
Communications Physics, Vol 4, Iss 1, Pp 1-9 (2021)
Local inversion symmetry breaking in centrosymmetric materials can lead to large spin polarization of the electronic band structure in separate sectors of the unit cell. Here, the authors reveal such hidden spin polarisation in ZrSiTe using spin and
Externí odkaz:
https://doaj.org/article/fc17eab23130477ea5c0e9104f8fc6c6
Autor:
Stefan Wirth, Julian Hebebrand, Raffaella Basilico, Ferco H. Berger, Ana Blanco, Cem Calli, Maureen Dumba, Ulrich Linsenmaier, Fabian Mück, Konraad H. Nieboer, Mariano Scaglione, Marc-André Weber, Elizabeth Dick
Publikováno v:
Insights into Imaging, Vol 11, Iss 1, Pp 1-18 (2020)
Abstract Background Although some national recommendations for the role of radiology in a polytrauma service exist, there are no European guidelines to date. Additionally, for many interdisciplinary guidelines, radiology tends to be under-represented
Externí odkaz:
https://doaj.org/article/2d615c37e61e41a9ae523dc4399790ed
Autor:
Justin H. Berger, Jennifer A. Faerber, Feiyan Chen, Kimberly Y. Lin, Julie A. Brothers, Michael L. O’Byrne
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 7 (2022)
Background Universal lipid screening in children provides an opportunity to mitigate the lifetime risk of atherosclerosis, particularly in children with chronic conditions that are predisposed to early atherosclerosis. In response, national guideline
Externí odkaz:
https://doaj.org/article/08721933edf34d59a79dee9bc14d2434