Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gyunghee Jo"'
Autor:
Ki-Baek Jeong, Minju Ryu, Jin-Sik Kim, Minsoo Kim, Jejoong Yoo, Minji Chung, Sohee Oh, Gyunghee Jo, Seong-Gyu Lee, Ho Min Kim, Mi-Kyung Lee, Seung-Wook Chi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Efficient screening of protein-drug interactions (PDIs) has been impeded by the limitations of current biophysical approaches. Here, the authors present a funneled YaxAB nanopore sensor which allows label-free, single-molecule detection of proteins a
Externí odkaz:
https://doaj.org/article/54c373ddae0b4cd79378d22673a63deb
Autor:
Gyunghee Jo, Jeomil Bae, Ho Jeong Hong, Ah-reum Han, Do-Kyun Kim, Seon Pyo Hong, Jung A Kim, Sangkyu Lee, Gou Young Koh, Ho Min Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Angiopoietin (Angpt)-Tie receptor 2 (Tie2) regulates vascular stability and is thus a potential therapeutic target in vascular diseases. Here, the authors report a Tie2-agonistic antibody which targets a site distinct from the Angpt 1-binding site an
Externí odkaz:
https://doaj.org/article/fc69bcd280cf4fe0bfa69e52efbb0a96
Autor:
Dain Kim, Sang Kyu Kim, Hyeseon Yoon, Hyo Jeong Hong, Heesu Chae, Jisu Hong, Jun-Yeol Yoon, Yoonjoo Choi, Gyunghee Jo, Chankyu Lee, Jemin Han
Publikováno v:
Journal of Microbiology and Biotechnology. 30:1760-1768
Vibrio cholerae, cause of the life-threatening diarrheal disease cholera, can be divided into different serogroups based on the structure of its lipopolysaccharide (LPS), which consists of lipid-A, corepolysaccharide and O-antigen polysaccharide (O-P
Publikováno v:
Angewandte Chemie. 132:23444-23451
Current approaches to design monodisperse protein assemblies require rigid, tight, and symmetric interactions between oligomeric protein units. Herein, we introduce a new multivalent-interaction-driven assembly strategy that allows flexible, spaced,
Autor:
Do-Kyun Kim, Gyunghee Jo, Gou Young Koh, Jung A. Kim, Seon Pyo Hong, Ho Min Kim, Ho Jeong Hong, Sangkyu Lee, Ah-reum Han, Jeomil Bae
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Angiopoietin (Angpt)-Tie receptor 2 (Tie2) plays key roles in vascular development and homeostasis as well as pathological vascular remodeling. Therefore, Tie2-agonistic antibody and engineered Angpt1 variants have been developed as potential therape
Autor:
Jimin Wi, Dain Kim, Heesu Chae, Chankyu Lee, Heeyoun Kim, Jun-Yeol Yoon, Sang Kyu Kim, Hyo Jeong Hong, Gyunghee Jo, Se-Ho Kim, Hyeseon Yoon
Publikováno v:
Journal of Microbiology and Biotechnology. 28:2113-2120
Cross-reactive material 197 (CRM₁₉₇) is a non-toxic mutant of diphtheria toxin containing a single amino acid substitution of glycine 52 with glutamic acid. CRM₁₉₇ has been used as a carrier protein for poorly immunogenic polysaccharide a
Autor:
Mun Sik Jeong, Hyo Jeong Hong, Doo Hyun Kim, Gyunghee Jo, Heesu Chae, Dain Kim, Kyun-Hwan Kim, Jun-Yeol Yoon, Jimin Wi, Sang Kyu Kim
Publikováno v:
Journal of Microbiology and Biotechnology. 28:1376-1383
The hepatitis B virus (HBV) envelope contains small (S), middle (M), and large (L) proteins. PreS1 of the L protein contains a receptor-binding motif crucial for HBV infection. This motif is highly conserved among 10 HBV genotypes (A-J), making it a
Autor:
Moon-Sik Shin, Sangkyu Kim, Min Soo Kim, Nam-Taek Lee, Donghwan Kim, Yoon-Won Kim, Hyo Jeong Hong, Jeongha Yoo, Jun-Yeol Yoon, Young-Jin Kim, Heui Keun Kang, Dain Kim, Gyunghee Jo
Publikováno v:
Biotechnology and Bioprocess Engineering. 22:114-119
Organophosphate (OP) nerve agents are known as the most toxic chemical warfare agents that act by inhibiting the enzyme acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Because BuChE is present at a level of about 3,900 times higher tha
Autor:
Dain, Kim, Hyeseon, Yoon, Sangkyu, Kim, Jimin, Wi, Heesu, Chae, Gyunghee, Jo, Jun-Yeol, Yoon, Heeyoun, Kim, Chankyu, Lee, Se-Ho, Kim, Hyo Jeong, Hong
Publikováno v:
Journal of microbiology and biotechnology. 28(12)
Cross-reactive material 197 (CRM₁₉₇) is a non-toxic mutant of diphtheria toxin containing a single amino acid substitution of glycine 52 with glutamic acid. CRM₁₉₇ has been used as a carrier protein for poorly immunogenic polysaccharide a