Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gyula Ficsor"'
Publikováno v:
Environmental and molecular mutagenesis. 26(1)
Monocrotaline is a very potent toxin, producing significant effects of pneumotoxicity, hepatotoxicity, and teratogenicity, as well as carcinogenicity. In addition, the compound has been clearly shown to be muta-genic after metabolic activation. The g
Publikováno v:
Mutation research. 264(4)
Chinese hamster ovary (CHO-WBLT) cells growing in McCoy's 5a with 10% fetal bovine serum (FBS) were adapted to 0.5% FBS in CHO-1 Complete Media System, a serum-free medium from Ventrex. Cells in these two media were exposed to 10−7 M and 10−8 M m
Publikováno v:
Mutation research. 264(2)
The polymerase chain reaction (PCR) can be used to amplify a mutation in a single sperm to a detectable level (Li et al., 1988). With modification, the PCR may allow for the development of a direct germ-cell mutation assay (Ficsor, 1988). We have enc
Publikováno v:
The Nurse Practitioner. 15:26
Acetowhitening of abnormal cervical epithelium has been suggested as an indicator of increased cervical cancer risk. The presence of human papillomavirus (HPV) types 16, 18, 31, 33 and 35 may also indicate increased cervical cancer risk. Hence, tests
Publikováno v:
Fertility and Sterility. 39:548-552
Sperm acrosin proteolytic activity in single sperm can be detected by a protein-free halo on a gelatin-substrate film. With current techniques, halos have variable sizes and are often absent because of unevenness of the hand-spread gelatin-substrate
Autor:
Gary F. Wertz, Gyula Ficsor
Publikováno v:
Environmental Health Perspectives
Previously we reported negative terata and c-mitosis synergism of FireMaster (polybrominated biphenyls) with colchicine in subacutely treated rats. Now we report absence of chromosome aberrations from FireMaster and absence of c-mitosis synergism of
Publikováno v:
Journal of Histochemistry & Cytochemistry. 32:63-66
A substrate-film method is described that allows the detection of hyaluronidase activity in nearly 100% of single human and mouse sperm. The level of hyaluronidase activity as determined by halo diameters was greater in mouse than in human sperm. Thi
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 57:77-84
Rhesus monkeys (Macaca mulatta) were used to determine their effectiveness as experimental animals for different cytogenetic tests with mitomycin C (MC). The micronucleus test (MNT) and/or chromosome analysis of blood and bone marrow were made before
Publikováno v:
Gamete Research. 12:75-84
Rat caproyl esterase (E.C.3.1.1.1), extracted from testis with Tween 80, was purified by cation exchange and lectin affinity chromatography. The 104-fold purified enzyme had an activity of 840 μmol/hr per mg protein. The purified esterase did not co
Autor:
Abraham Hsie, Eric Eisenstadt, Thomas H. Connor, Robert S. Stafford, John L. Seed, Gyula Ficsor, Michael G. Farrow, Robert Batzinger, Ernest Bueding, Marvin S. Legator
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 98:319-354
The methodologies and status of the Host-Mediated Assay were reviewed using the published literature available up to June 1980. The Working Group reviewed 274 documents, including abstracts, research articles, review articles, and publicly available