Zobrazeno 1 - 10
of 279
pro vyhledávání: '"Gyula Batta"'
Autor:
Adam Feher, Zoltán Pethő, Tibor G. Szanto, Álmos Klekner, Gabor Tajti, Gyula Batta, Tibor Hortobágyi, Zoltan Varga, Albrecht Schwab, Gyorgy Panyi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Glioblastoma (GBM) is the most aggressive glial tumor, where ion channels, including KCa1.1, are candidates for new therapeutic options. Since the auxiliary subunits linked to KCa1.1 in GBM are largely unknown we used electrophysiology combi
Externí odkaz:
https://doaj.org/article/cf1b43ce89b54546b3b0602f8f0ca7fc
Autor:
Ilona Bereczki, Vladimir Vimberg, Eszter Lőrincz, Henrietta Papp, Lajos Nagy, Sándor Kéki, Gyula Batta, Ana Mitrović, Janko Kos, Áron Zsigmond, István Hajdú, Zsolt Lőrincz, Dávid Bajusz, László Petri, Jan Hodek, Ferenc Jakab, György M. Keserű, Jan Weber, Lieve Naesens, Pál Herczegh, Anikó Borbás
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Patients infected with SARS-CoV-2 risk co-infection with Gram-positive bacteria, which severely affects their prognosis. Antimicrobial drugs with dual antiviral and antibacterial activity would be very useful in this setting. Although glycop
Externí odkaz:
https://doaj.org/article/91f0f017bd784a0087174f5750d3561a
Autor:
Beatrix Kocsis, Mi-Kyung Lee, Jae-Hyuk Yu, Tibor Nagy, Lajos Daróczi, Gyula Batta, István Pócsi, Éva Leiter
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Transcription factors (TFs) with the basic leucin zipper domain are key elements of the stress response pathways in filamentous fungi. In this study, we functionally characterized the two bZIP type TFs AtfA and AtfB by deletion (Δ) and overexpressio
Externí odkaz:
https://doaj.org/article/9d11f2af5c3e434e81d39423907d7c9d
Autor:
Mo’ath Yousef, Ildikó Szabó, József Murányi, Françoise Illien, Dóra Soltész, Csaba Bató, Gabriella Tóth, Gyula Batta, Péter Nagy, Sandrine Sagan, Zoltán Bánóczi
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 141 (2022)
Cell-penetrating peptides represent an emerging class of carriers capable of effective cellular delivery. This work demonstrates the preparation and investigation of efficient CPPs. We have already shown that the presence of 4-((4-(dimethylamino)phen
Externí odkaz:
https://doaj.org/article/4d7fc7b8b4d047cfb3506feb7a9f7d34
Autor:
Jimi M. Alex, Martin L. Rennie, Sylvain Engilberge, Gábor Lehoczki, Hajdu Dorottya, Ádám Fizil, Gyula Batta, Peter B. Crowley
Publikováno v:
IUCrJ, Vol 6, Iss 2, Pp 238-247 (2019)
Synthetic macrocycles such as calixarenes and cucurbiturils are increasingly applied as mediators of protein assembly and crystallization. The macrocycle can facilitate assembly by providing a surface on which two or more proteins bind simultaneously
Externí odkaz:
https://doaj.org/article/43b1441bed51482d8aeaf431095ccb11
Autor:
Florina Zakany, Mate Szabo, Gyula Batta, Levente Kárpáti, István M. Mándity, Péter Fülöp, Zoltan Varga, Gyorgy Panyi, Peter Nagy, Tamas Kovacs
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Although the largely positive intramembrane dipole potential (DP) may substantially influence the function of transmembrane proteins, its investigation is deeply hampered by the lack of measurement techniques suitable for high-throughput examination
Externí odkaz:
https://doaj.org/article/98dcad6a7d124987944ec77cc7e79849
Autor:
Ilona Bereczki, Zsolt Szűcs, Gyula Batta, Tamás Milán Nagy, Eszter Ostorházi, Katalin E. Kövér, Anikó Borbás, Pál Herczegh
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 77 (2022)
Various dimeric derivatives of the glycopeptide antibiotic teicoplanin were prepared with the aim of increasing the activity of the parent compound against glycopeptide-resistant bacteria, primarily vancomycin-resistant enterococci. Starting from tei
Externí odkaz:
https://doaj.org/article/3da40169d3d543cc84a3002057ef95a6
Autor:
Kuljeet Singh, Szabolcs Tarapcsák, Zsuzsanna Gyöngy, Zsuzsanna Ritter, Gyula Batta, Rosevalentine Bosire, Judit Remenyik, Katalin Goda
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2062 (2021)
P-glycoprotein (Pgp, ABCB1) is a member of one of the largest families of active transporter proteins called ABC transporters. Thanks to its expression in tissues with barrier functions and its broad substrate spectrum, it is an important determinant
Externí odkaz:
https://doaj.org/article/387776fb4e1142fba4dd2dcfea298dd4
Autor:
Ilona Bereczki, Henrietta Papp, Anett Kuczmog, Mónika Madai, Veronika Nagy, Attila Agócs, Gyula Batta, Márton Milánkovits, Eszter Ostorházi, Ana Mitrović, Janko Kos, Áron Zsigmond, István Hajdú, Zsolt Lőrincz, Dávid Bajusz, György Miklós Keserű, Jan Hodek, Jan Weber, Ferenc Jakab, Pál Herczegh, Anikó Borbás
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1111 (2021)
The protracted global COVID-19 pandemic urges the development of new drugs against the causative agent SARS-CoV-2. The clinically used glycopeptide antibiotic, teicoplanin, emerged as a potential antiviral, and its efficacy was improved with lipophil
Externí odkaz:
https://doaj.org/article/f24dbbab6dc04e6c8e451af15f46c4d7
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 8, Pp 1681-1691 (2017)
The dipole potential generating an electric field much stronger than any other type of membrane potential influences a wide array of phenomena, ranging from passive permeation to voltage-dependent conformational changes of membrane proteins. It is ge
Externí odkaz:
https://doaj.org/article/66c505eff6f14a978134da239ccb5b47