Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Gyula, Simig"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 653-659 (2022)
New approaches have been tested for the synthesis of lumateperone intermediates. As a result of these efforts, a novel synthesis of the late-stage tetracyclic key intermediate of lumateperone starting from the commercially available quinoxaline is de
Externí odkaz:
https://doaj.org/article/d17b83791c4a444e9567ef12d722146c
Autor:
Csilla Hargitai, Györgyi Koványi-Lax, Tamás Nagy, Péter Ábrányi-Balogh, András Dancsó, Gábor Tóth, Judit Halász, Angéla Pandur, Gyula Simig, Balázs Volk
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1636-1648 (2020)
Treatment of alkoxy-substituted o-(pivaloylaminomethyl)benzaldehydes under acidic conditions resulted in the formation of the regioisomeric aldehydes and/or dimer-like products. Detailed NMR studies and single-crystal X-ray measurements supported the
Externí odkaz:
https://doaj.org/article/4519f43ebccc4132b2066bfbe53f84d2
Autor:
Zsuzsanna Szokol, Károly Lozsi, Attila Virág, András Dancsó, László Szlávik, Gyula Simig, Balázs Volk
Publikováno v:
Periodica Polytechnica Chemical Engineering. 66:536-540
Blarcamesine is a promising investigational drug for the treatment of Alzheimer's disease. The international nonproprietary name blarcamesine refers to a racemic compound, although it seems likely that it will be marketed in an enantiopure form. A re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f403cc71b90b0a8167662de6a0c0fd86
https://doi.org/10.3311/ppch.20662
https://doi.org/10.3311/ppch.20662
Publikováno v:
Synthesis. 54:3201-3208
The significant pharmacological activity of 2,3-benzodiazepine-4-ones led to an increased interest in this compound family. However, the literature of the closely related 2,3,4-benzothiadiazepine 2,2-dioxides is rather scarce. Earlier we elaborated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10c69ebc37e608c93a5314ca4f9c19e8
https://doi.org/10.1055/a-1797-5298
https://doi.org/10.1055/a-1797-5298
Publikováno v:
Synthesis. 54:3874-3882
In the course of the synthesis of fused-ring analogues of the antidepressant drug tianeptine, representatives of three new heterocyclic ring systems, indolo[1,7-bc][1,2]benzothiazepines (and their 4,5-dihydro analogues), 5,6-dihydroquino[1,8-bc][1,2]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::409ca0d6831f461a061347bd4201f46f
https://doi.org/10.1055/s-0040-1719885
https://doi.org/10.1055/s-0040-1719885
Autor:
Györgyi Koványi-Lax, Csilla Hargitai, Péter Ábrányi-Balogh, Tamás Nagy, Gábor Tóth, Zsófia Garádi, Gábor Németh, Angéla Pandur, Simon Horváth, András Dancsó, Gyula Simig, Balázs Volk
Publikováno v:
Organic & Biomolecular Chemistry. 20:1933-1944
In the present study, reactions of ortho-(pivaloylaminomethyl)benzaldehydes are described with boron trifluoride diethyl etherate used as the catalyst, leading to two unexpected products.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5038185b7756bd5ffe658f2520286b4
https://doi.org/10.1039/d1ob02308j
https://doi.org/10.1039/d1ob02308j
Publikováno v:
ARKIVOC, Vol 2015, Iss 4, Pp 127-138 (2015)
Externí odkaz:
https://doaj.org/article/3dcc789d672d414cad5381b54518a270
Publikováno v:
Tetrahedron. :133466
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cde3efad84eb935e66741e60ab6cd757
https://doi.org/10.1016/j.tet.2023.133466
https://doi.org/10.1016/j.tet.2023.133466
Publikováno v:
Magyar Kémiai Folyóirat. 127:82-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a94b2375b33cf44244172027df0f5690
https://doi.org/10.24100/mkf.2021.02.82
https://doi.org/10.24100/mkf.2021.02.82
Autor:
Gyula Simig, Márta Porcs-Makkay, Gyöngyvér Pusztai, Gergő Szabó, László Nyulászi, András Dancsó, Balázs Volk, Gábor Tóth, Judit Halász, Imre Gyűjtő, Zsolt Kelemen
Publikováno v:
The Journal of Organic Chemistry
The base-induced (t-BuOK) rearrangement reactions of 3,4-dihydro-2H-1,2,3-benzothiadiazine 1,1-dioxides result in a ring opening along the N-N bond, followed by ring closure with the formation of new C-N bonds. The position of the newly formed C-N bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08286733574d3f4a30d329f3476dd48c
http://europepmc.org/articles/PMC8021225
http://europepmc.org/articles/PMC8021225