Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gyu Hyun Nam"'
Autor:
Gyu Hyun Nam1,2, Do-Hyung Kim1,2, Nam-Chul Ha2,3, Do Soo Jang1,2, Young Sung Yun1,2, Bee Hak Hong1,2, Byung-Ha Oh2,3, Kwan Yong Choi1,2 kchoi@postech.ac.kr
Publikováno v:
Journal of Biochemistry. Jul2003, Vol. 134 Issue 1, p101-110. 10p. 4 Diagrams, 6 Charts, 3 Graphs.
Publikováno v:
FEBS Journal. 272:1999-2011
A structural motif called the small exterior hydrophobic cluster (SEHC) has been proposed to explain the stabilizing effect mediated by solvent-exposed hydrophobic residues; however, little is known about its biological roles. Unusually, in Δ5-3-ket
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9c4b0ac9a4843b0657d1d57d3422e39
https://doi.org/10.1111/j.1742-4658.2005.04627.x
https://doi.org/10.1111/j.1742-4658.2005.04627.x
Autor:
Gyu Hyun Nam, Bee Hak Hong, Kwan Yong Choi, Sun Shin Cha, Young Sung Yun, Heung-Soo Lee, Yun Hee Oh
Publikováno v:
Biochemical Journal. 375:297-305
KSI (ketosteroid isomerase) from Comamonas testosteroni is a homodimeric enzyme that catalyses the allylic isomerization of Delta5-3-ketosteroids to their conjugated Delta4-isomers at a reaction rate equivalent to the diffusion-controlled limit. Base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f039e0b28b70195fa815c7102c2917
https://doi.org/10.1042/bj20030263
https://doi.org/10.1042/bj20030263
Autor:
Kwan Yong Choi, Gyu Hyun Nam
Publikováno v:
European Journal of Biochemistry. 269:5280-5287
Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) has been known to induce tumor-specific apoptosis and to share the structural and functional characteristics with the proteins of TNF family. Recently, the crystal structure of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::706353bfd468a7eeba7048a35f4f66ad
https://doi.org/10.1046/j.1432-1033.2002.03242.x
https://doi.org/10.1046/j.1432-1033.2002.03242.x
Autor:
Man K. Song, You Suk Suh, Gyu Hyun Nam, Sung H. Lee, Kwan Yong Choi, Gildon Choi, Won Bae Kim, Chu H. Lee, Sang J. Ha, Young Chul Sung, Hyun Tak Jin, Jun Chang
Publikováno v:
Nature Biotechnology. 20:381-386
Interleukin-12 (IL-12), consisting of p40 and p35 subunits, produces both p70 heterodimer and free p40. p70 is essential for the induction of T-helper 1 (Th1) and cytotoxic T-cell (CTL) immunity, whereas p40 inhibits p70-mediated function. Here, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b169e0fb48bc06f82267554a81581ff9
https://doi.org/10.1038/nbt0402-381
https://doi.org/10.1038/nbt0402-381
Publikováno v:
Biochemistry. 40:5011-5017
Ketosteroid isomerase (KSI) from Comamonas testosteroni is a homodimeric enzyme with 125 amino acids in each monomer catalyzing the allylic isomerization reaction at rates comparable to the diffusion limit. Kinetic analysis of KSI refolding has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd837155f38ba8b3c6976fc675ebc621
https://doi.org/10.1021/bi0019139
https://doi.org/10.1021/bi0019139
Autor:
Jae-Hyun Cho, Sunggoo Yun, Kwan Yong Choi, Gyu Hyun Nam, Gildon Choi, Hee Cheon Lee, Do Hyung Kim, Do Soo Jang
Publikováno v:
Biochemistry. 39:13084-13092
Equilibrium and kinetic analyses have been carried out to elucidate the folding mechanism of homodimeric ketosteroid isomerase (KSI) from Comamonas testosteroni. The folding of KSI was reversible since the activity as well as the fluorescence and CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2086fb17ac617292dd46066405d9b4de
https://doi.org/10.1021/bi000872d
https://doi.org/10.1021/bi000872d
Autor:
Byung-Ha Oh, Kwan Yong Choi, Jeong-Sun Kim, Do Hyung Kim, Gildon Choi, Min Sung Kim, Gyu Hyun Nam, Do Soo Jang, Nam-Chul Ha
Publikováno v:
Biochemistry. 39:4581-4589
Delta(5)-3-Ketosteroid isomerase from Pseudomonas putida biotype B is one of the most proficient enzymes catalyzing an allylic isomerization reaction at rates comparable to the diffusion limit. The hydrogen-bond network (Asp99... Wat504...Tyr14...Tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7109f5a4c2ee015d7c4cc207b0ddfb01
https://doi.org/10.1021/bi992119u
https://doi.org/10.1021/bi992119u
Autor:
Nam-Chul Ha, Bee Hak Hong, Kwan Yong Choi, Gyu Hyun Nam, Do Hyung Kim, Byung-Ha Oh, Young Sung Yun, Do Soo Jang
Publikováno v:
Journal of biochemistry. 134(1)
Ketosteroid isomerase (KSI) from Pseudomonas putida biotype B is a homodimeric enzyme catalyzing an allylic isomerization of Delta(5)-3-ketosteroids at a rate of the diffusion-controlled limit. The dimeric interactions mediated by Arg72, Glu118, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b10c77e0340400af4ba82ddd350ead
https://pubmed.ncbi.nlm.nih.gov/12944376
https://pubmed.ncbi.nlm.nih.gov/12944376
Autor:
Sejeong Shin, Do Soo Jang, Kwan Yong Choi, Byung-Ha Oh, Gyu Hyun Nam, Tae-Hee Lee, Young Sung Yun
Publikováno v:
The Journal of biological chemistry. 278(30)
Two homologous Δ5-3-ketosteroid isomerases from Comamonas testosteroni (TI-WT) and Pseudomonas putida biotype B (PI-WT) exhibit different pH activity profiles. TI-WT loses activity below pH 5.0 due to the protonation of the conserved catalytic base,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f3bf660eca48b90048a187b5432b7e
https://pubmed.ncbi.nlm.nih.gov/12734184
https://pubmed.ncbi.nlm.nih.gov/12734184