Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Gyorgy Babnigg"'
Autor:
Doga Yamac Ozgulbas, Don Jensen, Rory Butler, Rafael Vescovi, Ian T. Foster, Michael Irvin, Yasukazu Nakaye, Miaoqi Chu, Eric M. Dufresne, Soenke Seifert, Gyorgy Babnigg, Arvind Ramanathan, Qingteng Zhang
Publikováno v:
Light: Science & Applications, Vol 12, Iss 1, Pp 1-10 (2023)
Abstract The dynamics and structure of mixed phases in a complex fluid can significantly impact its material properties, such as viscoelasticity. Small-angle X-ray Photon Correlation Spectroscopy (SA-XPCS) can probe the spontaneous spatial fluctuatio
Externí odkaz:
https://doaj.org/article/eb3a8e0e14dc438dbe84190239a36835
Autor:
Paul Hanke, Bruce Parrello, Olga Vasieva, Chase Akins, Philippe Chlenski, Gyorgy Babnigg, Chris Henry, Fatima Foflonker, Thomas Brettin, Dionysios Antonopoulos, Rick Stevens, Michael Fonstein
Publikováno v:
Metabolic Engineering Communications, Vol 17, Iss , Pp e00225- (2023)
The goal of this study is to develop a general strategy for bacterial engineering using an integrated synthetic biology and machine learning (ML) approach. This strategy was developed in the context of increasing L-threonine production in Escherichia
Externí odkaz:
https://doaj.org/article/7ecd1b4b29bf4bb09dc4bf3fb35386f3
Autor:
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O’Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The development of direct-acting antivirals to combat COVID-19 remains an important goal. Here the authors design covalent inhibitors that target the papain-like protease from SARS-CoV-2. The most promising inhibitor blocks viral replication in mamma
Externí odkaz:
https://doaj.org/article/fd261a622e08487782f550c5d0f5bc31
Autor:
Darren A. Sherrell, Alex Lavens, Mateusz Wilamowski, Youngchang Kim, Ryan Chard, Krzysztof Lazarski, Gerold Rosenbaum, Rafael Vescovi, Jessica L. Johnson, Chase Akins, Changsoo Chang, Karolina Michalska, Gyorgy Babnigg, Ian Foster, Andrzej Joachimiak
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 5, Pp 1141-1151 (2022)
Serial synchrotron crystallography enables the study of protein structures under physiological temperature and reduced radiation damage by collection of data from thousands of crystals. The Structural Biology Center at Sector 19 of the Advanced Photo
Externí odkaz:
https://doaj.org/article/73d049967fd442e49c02f129554585bf
Autor:
Kemin Tan, Min Zhou, Robert P. Jedrzejczak, Ruiying Wu, Raul A. Higuera, Dominika Borek, Gyorgy Babnigg, Andrzej Joachimiak
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 14-24 (2020)
The recently discovered antibiotic teixobactin is produced by uncultured soil bacteria. The antibiotic inhibits cell wall synthesis of Gram-positive bacteria by binding to precursors of cell wall building blocks, and therefore it is thought to be les
Externí odkaz:
https://doaj.org/article/fa10c6e1bbae4aabb592b0fa413c8b9d
Autor:
Marie-Francoise Noirot-Gros, Shalaka V. Shinde, Chase Akins, Jessica L. Johnson, Sarah Zerbs, Rosemarie Wilton, Kenneth M. Kemner, Philippe Noirot, Gyorgy Babnigg
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Coupling microfluidics with microscopy has emerged as a powerful approach to study at cellular resolution the dynamics in plant physiology and root-microbe interactions (RMIs). Most devices have been designed to study the model plant Arabidopsis thal
Externí odkaz:
https://doaj.org/article/06443e54b6914310b2a031e63e8ee730
Autor:
Thibault Annaval, Jeffrey D. Rudolf, Chin-Yuan Chang, Jeremy R. Lohman, Youngchang Kim, Lance Bigelow, Robert Jedrzejczak, Gyorgy Babnigg, Andrzej Joachimiak, George N. Phillips, Ben Shen
Publikováno v:
ACS Omega, Vol 2, Iss 8, Pp 5159-5169 (2017)
Externí odkaz:
https://doaj.org/article/f93dca24cda6473ab72e51f3e5444751
Autor:
Ana Lilia Juárez-Vázquez, Janaka N Edirisinghe, Ernesto A Verduzco-Castro, Karolina Michalska, Chenggang Wu, Lianet Noda-García, Gyorgy Babnigg, Michael Endres, Sofía Medina-Ruíz, Julián Santoyo-Flores, Mauricio Carrillo-Tripp, Hung Ton-That, Andrzej Joachimiak, Christopher S Henry, Francisco Barona-Gómez
Publikováno v:
eLife, Vol 6 (2017)
The connection between gene loss and the functional adaptation of retained proteins is still poorly understood. We apply phylogenomics and metabolic modeling to detect bacterial species that are evolving by gene loss, with the finding that Actinomyce
Externí odkaz:
https://doaj.org/article/8757720966d641749ea07358e6bb7cad
Autor:
Hongnan Cao, Kemin Tan, Fengbin Wang, Lance Bigelow, Ragothaman M. Yennamalli, Robert Jedrzejczak, Gyorgy Babnigg, Craig A. Bingman, Andrzej Joachimiak, Madan K. Kharel, Shanteri Singh, Jon S. Thorson, George N. Phillips Jr.
Publikováno v:
Structural Dynamics, Vol 3, Iss 3, Pp 034702-034702-12 (2016)
CalE6 from Micromonospora echinospora is a (pyridoxal 5′ phosphate) PLP-dependent methionine γ-lyase involved in the biosynthesis of calicheamicins. We report the crystal structure of a CalE6 2-(N-morpholino)ethanesulfonic acid complex showing lig
Externí odkaz:
https://doaj.org/article/4955a733f0f04c6185ca09254f46c927
Autor:
Youngchang Kim, Christine Tesar, Joseph Mire, Robert Jedrzejczak, Andrew Binkowski, Gyorgy Babnigg, James Sacchettini, Andrzej Joachimiak
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24621 (2011)
The New Delhi Metallo-β-lactamase (NDM-1) gene makes multiple pathogenic microorganisms resistant to all known β-lactam antibiotics. The rapid emergence of NDM-1 has been linked to mobile plasmids that move between different strains resulting in wo
Externí odkaz:
https://doaj.org/article/cb105b64899e41dd9b493fb98818bf62