Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gyorgy, Csordas"'
Autor:
César Vásquez-Trincado, Julia Dunn, Ji In Han, Briyanna Hymms, Jaclyn Tamaroff, Monika Patel, Sara Nguyen, Anna Dedio, Kristin Wade, Chinazo Enigwe, Zuzana Nichtova, David R. Lynch, Gyorgy Csordas, Shana E. McCormack, Erin L. Seifert
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Friedreich’s ataxia (FRDA) is an inherited disorder caused by reduced levels of frataxin (FXN), which is required for iron-sulfur cluster biogenesis. Neurological and cardiac comorbidities are prominent and have been a major focus of study. Skeleta
Externí odkaz:
https://doaj.org/article/d8ce409b580d48b49f4391b0d76d2a4c
Autor:
Richard T. Clements, Radmila Terentyeva, Shanna Hamilton, Paul M. L. Janssen, Karim Roder, Benjamin Y. Martin, Fruzsina Perger, Timothy Schneider, Zuzana Nichtova, Anindhya S. Das, Roland Veress, Beth S. Lee, Do-Gyoon Kim, Gideon Koren, Matthew S. Stratton, Gyorgy Csordas, Federica Accornero, Andriy E. Belevych, Sandor Gyorke, Dmitry Terentyev
Publikováno v:
Basic Research in Cardiology. 118
Calcium transfer into the mitochondrial matrix during sarcoplasmic reticulum (SR) Ca2+ release is essential to boost energy production in ventricular cardiomyocytes (VCMs) and match increased metabolic demand. Mitochondria from female hearts exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbc16c7193cf2b8cedadcf67efa7dafc
https://doi.org/10.1007/s00395-023-00988-1
https://doi.org/10.1007/s00395-023-00988-1
Autor:
Shanna Hamilton, Radmila Terentyeva, Roland Veress, Fruzsina Perger, Zuzana Nichtova, Benjamin Martin, Sandor Gyorke, Andriy Belevych, Gyorgy Csordas, Dmitry Terentyev
Publikováno v:
Circulation Research. 131
Intracellular Ca 2+ cycling in ventricular myocytes (VMs) is tightly linked to mitochondrial metabolic output, and disturbances in this coupling contribute to cardiac arrhythmias. We recently demonstrated in the heritable arrhythmia syndrome catechol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e082521adb52c46df41c68c16318a4e4
https://doi.org/10.1161/res.131.suppl_1.p1083
https://doi.org/10.1161/res.131.suppl_1.p1083
Autor:
Shanna Hamilton, Radmila Terentyeva, Roland Veress, Fruzsina Perger, Zuzana Nichtova, Benjamin Martin, Sandor Gyorke, Andriy E. Belevych, Gyorgy Csordas, Dmitry Terentyev
Publikováno v:
Biophysical Journal. 122:378a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45f7d19533c43ddd7fa59f6fd7d6ec84
https://doi.org/10.1016/j.bpj.2022.11.2078
https://doi.org/10.1016/j.bpj.2022.11.2078
Autor:
John Elrod, Gyorgy Csordas, Jonathan Lambert, Sergio De la Fuente, Celia Fernández Sanz, Celia Fernandez-Sanz, Zuzana Nichtova
Publikováno v:
Cell Reports, Vol 24, Iss 12, Pp 3099-3107.e4 (2018)
Cell reports
Cell reports
SUMMARY Mitochondrial Ca2+ elevations enhance ATP production, but uptake must be balanced by efflux to avoid overload. Uptake is mediated by the mitochondrial Ca2+ uniporter channel complex (MCUC), and extrusion is controlled largely by the Na+/Ca2+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdddbc1dc64df85e08d87b6e114aeb1
http://www.sciencedirect.com/science/article/pii/S2211124718313111
http://www.sciencedirect.com/science/article/pii/S2211124718313111
Publikováno v:
J Biol Chem
The mitochondrial matrix ATPase associated with diverse cellular activities (m-AAA) protease spastic paraplegia 7 (SPG7) has been recently implicated as either a negative or positive regulatory component of the mitochondrial permeability transition p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7997874b176009c64dd29f7645be2c2
https://pubmed.ncbi.nlm.nih.gov/31097542
https://pubmed.ncbi.nlm.nih.gov/31097542
Autor:
Sergio de la Fuente, Caitlin Vail, Elorm J Agra, Kira Holmstrom, Junhui Sun, Jyotsna Mishra, Toren Finkel, Elizabeth Murphy, Shey-Shing Sheu, Gyorgy Csordas
Publikováno v:
Circulation Research. 117
Propagation of SR-derived Ca2+ signals to the mitochondrial matrix is an important tuning tool of cardiac energy metabolism (excitation-bioenergetics coupling). Effective activation of the low-affinity mitochondrial Ca2+ uniporter (mtCU) is supported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c5fbcec7123a8fa48942f16c2c9a3bc
https://doi.org/10.1161/res.117.suppl_1.240
https://doi.org/10.1161/res.117.suppl_1.240
Autor:
Cherlin, Tess1,2 (AUTHOR), Jing, Yi1 (AUTHOR), Shah, Siddhartha1 (AUTHOR), Kennedy, Anne1,3 (AUTHOR), Telonis, Aristeidis G.1,4 (AUTHOR), Pliatsika, Venetia1,5 (AUTHOR), Wilson, Haley1,3 (AUTHOR), Thompson, Lily1,6 (AUTHOR), Vlantis, Panagiotis I.1,7 (AUTHOR), Loher, Phillipe1 (AUTHOR), Leiby, Benjamin8 (AUTHOR), Rigoutsos, Isidore1 (AUTHOR) isidore.rigoutsos@jefferson.edu
Publikováno v:
BMC Biology. 9/12/2024, Vol. 22 Issue 1, p1-21. 21p.
Publikováno v:
Circulation. 116
Propagation of ryanodine receptor (RyR) dependent SR Ca2+ release to the mitochondria is locally supported by high [Ca2+] microdomains at close contacts between the organelles. The objective of this study was to clarify if the close associations of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d5f482aa0c0d62cfbaaa7c08e1e79fd
https://doi.org/10.1161/circ.116.suppl_16.ii_35
https://doi.org/10.1161/circ.116.suppl_16.ii_35
Publikováno v:
In Biophysical Journal 28 January 2014 106(2) Supplement 1:592a-592a