Zobrazeno 1 - 10
of 1 547
pro vyhledávání: '"Gynther, M."'
Autor:
Puris E; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Heidelberg, Germany., Saveleva L; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Auriola S; School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Gynther M; School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Kanninen KM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Heidelberg, Germany.
Publikováno v:
Frontiers in pharmacology [Front Pharmacol] 2024 Mar 20; Vol. 15, pp. 1365051. Date of Electronic Publication: 2024 Mar 20 (Print Publication: 2024).
Autor:
Ramirez, Y.P., Mladek, A.C., Phillips, Roger M., Gynther, M., Rautio, J., Ross, A.H., Wheelhouse, Richard T., Sakaria, J.N.
Yes
The cellular responses to two new temozolomide (TMZ) analogues, DP68 and DP86, acting against glioblastoma multiforme (GBM) cell lines and primary culture models are reported. Dose–response analysis of cultured GBM cells revealed that DP68
The cellular responses to two new temozolomide (TMZ) analogues, DP68 and DP86, acting against glioblastoma multiforme (GBM) cell lines and primary culture models are reported. Dose–response analysis of cultured GBM cells revealed that DP68
Externí odkaz:
http://hdl.handle.net/10454/7235
Autor:
Puris E; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Petralla S; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Auriola S; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Kidron H; Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Viikinkaari 5 E, P.O. Box 56, Helsinki, 00014, Finland., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Gynther M; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany. Electronic address: mikko.gynther@uni-heidelberg.de.
Publikováno v:
Journal of pharmaceutical sciences [J Pharm Sci] 2023 Sep; Vol. 112 (9), pp. 2581-2590. Date of Electronic Publication: 2023 May 21.
Autor:
Suominen L; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland., Sjöstedt N; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland., Vellonen KS; School of Pharmacy, University of Eastern Finland, Kuopio FI-70210, Finland., Gynther M; School of Pharmacy, University of Eastern Finland, Kuopio FI-70210, Finland., Auriola S; School of Pharmacy, University of Eastern Finland, Kuopio FI-70210, Finland., Kidron H; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland. Electronic address: heidi.kidron@helsinki.fi.
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2023 Sep 01; Vol. 188, pp. 106527. Date of Electronic Publication: 2023 Jul 13.
Autor:
Puris, E., Auriola, S., Petralla, S., Hartman, R., Gynther, M., Lange, E.C.M. de, Fricker, G.
Publikováno v:
Neurobiology of Disease, 169
There is growing evidence that membrane transporters expressed at the blood-brain barrier (BBB) and brain parenchymal cells play an important role in Alzheimer's disease (AD) development and progression. However, quantitative information about change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1b2072a5a886c08ecf76316b97637c
https://doi.org/10.1016/j.nbd.2022.105741
https://doi.org/10.1016/j.nbd.2022.105741
Autor:
Eteläinen TS; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Silva MC; Chemical Neurobiology Laboratory, Departments of Neurology and Psychiatry, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Uhari-Väänänen JK; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., De Lorenzo F; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Jäntti MH; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Cui H; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio 70211, Finland., Chavero-Pieres M; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Kilpeläinen T; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Mechtler C; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Svarcbahs R; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Seppälä E; School of Medicine / Biomedicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio 70211, Finland., Savinainen JR; School of Medicine / Biomedicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio 70211, Finland., Puris E; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls University, Heidelberg D-69120, Germany., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls University, Heidelberg D-69120, Germany., Gynther M; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls University, Heidelberg D-69120, Germany., Julku UH; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland., Huttunen HJ; Neuroscience Center, University of Helsinki, Helsinki 00014, Finland.; Herantis Pharma Plc., Espoo 02600, Finland., Haggarty SJ; Chemical Neurobiology Laboratory, Departments of Neurology and Psychiatry, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Myöhänen TT; Division of Pharmacology and Pharmacotherapy/Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki 00014, Finland.; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio 70211, Finland.
Publikováno v:
Science translational medicine [Sci Transl Med] 2023 Apr 12; Vol. 15 (691), pp. eabq2915. Date of Electronic Publication: 2023 Apr 12.
Autor:
Puris E; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Gynther M; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany.
Publikováno v:
Pharmaceutics [Pharmaceutics] 2023 Jan 21; Vol. 15 (2). Date of Electronic Publication: 2023 Jan 21.
Autor:
Gynther M; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Estrada ML; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Loppi S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland.; Department of Immunobiology, University of Arizona, 1656 E Mabel Street, Tucson, AZ 85724-5221, USA., Korhonen P; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Kanninen KM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Malm T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Koistinaho J; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland.; Neuroscience Center, Helsinki Institute for Life Science, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland., Auriola S; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Puris E; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany.
Publikováno v:
Pharmaceutics [Pharmaceutics] 2022 Nov 10; Vol. 14 (11). Date of Electronic Publication: 2022 Nov 10.
Autor:
Puris E; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany. Electronic address: elena.puris@uni-heidelberg.de., Kouřil Š; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900 Olomouc, Czech Republic; Department of Clinical Biochemistry, University Hospital Olomouc, I.P. Pavlova 6, 77900 Olomouc, Czech Republic., Najdekr L; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900 Olomouc, Czech Republic., Auriola S; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Loppi S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Department of Immunobiology, University of Arizona, 1656 E Mabel Street, Tucson, AZ 85724-5221, United States., Korhonen P; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Gómez-Budia M; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany., Kanninen KM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Malm T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Friedecký D; Institute of Molecular and Translational Medicine, Palacký University Olomouc, Hněvotínská 5, 77900 Olomouc, Czech Republic; Department of Clinical Biochemistry, University Hospital Olomouc, I.P. Pavlova 6, 77900 Olomouc, Czech Republic., Gynther M; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120 Heidelberg, Germany.
Publikováno v:
Neuroscience [Neuroscience] 2022 Aug 01; Vol. 496, pp. 165-178. Date of Electronic Publication: 2022 May 28.
Autor:
Puris E; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120, Heidelberg, Germany. elena.puris@uni-heidelberg.de., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120, Heidelberg, Germany., Gynther M; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Im Neuenheimer Feld 329, 69120, Heidelberg, Germany.
Publikováno v:
Pharmaceutical research [Pharm Res] 2022 Jul; Vol. 39 (7), pp. 1415-1455. Date of Electronic Publication: 2022 Mar 31.