Zobrazeno 1 - 10
of 13
pro vyhledávání: '"György Trencsenyi"'
Autor:
Gergely Farkasinszky, Judit Szabó Péliné, Péter Károlyi, Szilvia Rácz, Noémi Dénes, Tamás Papp, József Király, Zsuzsanna Szabo, István Kertész, Gábor Mező, Gabor Halmos, Zita Képes, György Trencsényi
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 542 (2024)
Background: To better understand ischaemia-related molecular alterations, temporal changes in angiogenic Aminopeptidase N (APN/CD13) expression and glucose metabolism were assessed with PET using a rat model of peripheral arterial disease (PAD). Meth
Externí odkaz:
https://doaj.org/article/2922067021fc41558236fb02f2d7df70
Autor:
Dániel Szücs, Judit P. Szabó, Viktória Arató, Barbara Gyuricza, Dezső Szikra, Imre Tóth, Zita Képes, György Trencsényi, Anikó Fekete
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1280 (2023)
Although radiolabeled alpha-melanocyte stimulating hormone-analogue NAPamide derivatives are valuable melanoma-specific diagnostic probes, their rapid elimination kinetics and high renal uptake may preclude them from being used in clinical settings.
Externí odkaz:
https://doaj.org/article/239947dec2ce4685ab9b018181f7ad52
Publikováno v:
Bioengineering, Vol 10, Iss 5, p 521 (2023)
Until now, very few efforts have been made to specifically trace, monitor, and visualize implantations, artificial organs, and bioengineered scaffolds for tissue engineering in vivo. While mainly X-Ray, CT, and MRI methods have been used for this pur
Externí odkaz:
https://doaj.org/article/f164b8bd6fd2481781b3575748394457
Autor:
Zita Képes, Viktória Arató, Judit P. Szabó, Barbara Gyuricza, Dániel Szücs, István Hajdu, Anikó Fekete, Frank Bruchertseifer, Dezső Szikra, György Trencsényi
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 491 (2023)
Since NGR-tripeptides (asparagine-glycine-arginine) selectively target neoangiogenesis-associated Aminopeptidase N (APN/CD13) on cancer cells, we aimed to evaluate the in vivo tumour targeting capability of radiolabelled, NGR-containing, ANP/CD13-sel
Externí odkaz:
https://doaj.org/article/8ca79fa801d74f959e5e623041f91f7f
Autor:
Csaba Csikos, Adrienn Vágner, Gábor Nagy, Ibolya Kálmán-Szabó, Judit P. Szabó, Minh Toan Ngo, Zoltán Szoboszlai, Dezső Szikra, Zoárd Tibor Krasznai, György Trencsényi, Ildikó Garai
Publikováno v:
Diagnostics, Vol 13, Iss 2, p 236 (2023)
Among humanized monoclonal antibodies, bevacizumab specifically binds to vascular endothelial growth factor A (VEGF-A). VEGF-A is an overexpressed biomarker in cervix carcinoma and is involved in the development and maintenance of tumor-associated ne
Externí odkaz:
https://doaj.org/article/061d48f6b31f4c4cbe486fb6af77407b
Autor:
Barbara Gyuricza, Ágnes Szűcs, Judit P. Szabó, Viktória Arató, Zita Képes, Dániel Szücs, Dezső Szikra, György Trencsényi, Anikó Fekete
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2504 (2022)
Given that galectin-3 (Gal-3) is a β-galactoside-binding lectin promoting tumor growth and metastatis, it could be a valuable target for the treatment of Gal-3-expressing neoplasms. An aromatic group introduced to the C-3′ position of lactosamine
Externí odkaz:
https://doaj.org/article/f1525be97eff46a4b568335f6152c85a
Autor:
Dániel Szücs, Tibor Csupász, Judit P. Szabó, Adrienn Kis, Barbara Gyuricza, Viktória Arató, Viktória Forgács, Adrienn Vágner, Gábor Nagy, Ildikó Garai, Dezső Szikra, Imre Tóth, György Trencsényi, Gyula Tircsó, Anikó Fekete
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 666 (2022)
Hypoxia promotes angiogenesis, which is crucial for tumor growth, and induces malignant progression and increases the therapeutic resistance. Positron emission tomography (PET) enables the detection of the hypoxic regions in tumors using 2-nitroimida
Externí odkaz:
https://doaj.org/article/843f4628244a414b8a57736cdc4ebaed
Autor:
Viktória Forgács, Anikó Fekete, Barbara Gyuricza, Dániel Szücs, György Trencsényi, Dezső Szikra
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 147 (2022)
Cyclotron-produced radiometals must be separated from the irradiated target and purified from other metal impurities, which could interfere with the radiolabeling process. We compared different chromatographic and colorimetric methods to determine th
Externí odkaz:
https://doaj.org/article/26e2b31d06d24e9e845d363fdffdb581
Autor:
Gábor Szalóki, Zoárd T Krasznai, Ágnes Tóth, Laura Vízkeleti, Attila G Szöllősi, György Trencsényi, Imre Lajtos, István Juhász, Zoltán Krasznai, Teréz Márián, Margit Balázs, Gábor Szabó, Katalin Goda
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107875 (2014)
P-glycoprotein (Pgp) extrudes a large variety of chemotherapeutic drugs from the cells, causing multidrug resistance (MDR). The UIC2 monoclonal antibody recognizes human Pgp and inhibits its drug transport activity. However, this inhibition is partia
Externí odkaz:
https://doaj.org/article/3470007aea544df980b1d9799a7c5211
Autor:
Mónika Gönczi, Zsolt Ráduly, László Szabó, János Fodor, Andrea Telek, Nóra Dobrosi, Norbert Balogh, Péter Szentesi, Gréta Kis, Miklós Antal, György Trencsenyi, Beatrix Dienes, László Csernoch
Publikováno v:
eLife, Vol 11 (2022)
Today septins are considered as the fourth component of the cytoskeleton, with the Septin7 isoform playing a critical role in the formation of higher-order structures. While its importance has already been confirmed in several intracellular processes
Externí odkaz:
https://doaj.org/article/7fcf647b45d74eaabf122d7ffd223932