Zobrazeno 1 - 10
of 198
pro vyhledávání: '"György Kéri"'
Autor:
Johannes Brägelmann, Marcel A. Dammert, Felix Dietlein, Johannes M. Heuckmann, Axel Choidas, Stefanie Böhm, André Richters, Debjit Basu, Verena Tischler, Carina Lorenz, Peter Habenberger, Zhizhou Fang, Sandra Ortiz-Cuaran, Frauke Leenders, Jan Eickhoff, Uwe Koch, Matthäus Getlik, Martin Termathe, Muhammad Sallouh, Zoltán Greff, Zoltán Varga, Hyatt Balke-Want, Christopher A. French, Martin Peifer, H. Christian Reinhardt, László Örfi, György Kéri, Sascha Ansén, Lukas C. Heukamp, Reinhard Büttner, Daniel Rauh, Bert M. Klebl, Roman K. Thomas, Martin L. Sos
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2833-2845 (2017)
Kinase inhibitors represent the backbone of targeted cancer therapy, yet only a limited number of oncogenic drivers are directly druggable. By interrogating the activity of 1,505 kinase inhibitors, we found that BRD4-NUT-rearranged NUT midline carcin
Externí odkaz:
https://doaj.org/article/65260813004b4d5e8d198b9f59d2baa6
Autor:
Diána Brauswetter, Bianka Gurbi, Attila Varga, Edit Várkondi, Richárd Schwab, Gábor Bánhegyi, Orsolya Fábián, György Kéri, István Vályi-Nagy, István Peták
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185687 (2017)
Pancreatic cancer is an increasing cause of cancer related death worldwide. KRAS is the dominant oncogene in this cancer type and molecular rationale would indicate, that inhibitors of the downstream target MEK could be appropriate targeted agents, b
Externí odkaz:
https://doaj.org/article/a86dc0d78bea4e2a92e9c631ca56458e
Autor:
Robert Torka, Kinga Pénzes, Simone Gusenbauer, Christine Baumann, István Szabadkai, Lászlȯ Őrfi, György Kéri, Axel Ullrich
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 4, Pp 301-318 (2014)
The Axl receptor tyrosine kinase (RTK) has been established as a strong candidate for targeted therapy of cancer. However, the benefits of targeted therapies are limited due to acquired resistance and activation of alternative RTKs. Therefore, we ask
Externí odkaz:
https://doaj.org/article/a3ed0e9a922e4bc19ad5113c9080010a
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144792 (2015)
Externí odkaz:
https://doaj.org/article/55ac64e255ec4adb9ce3d6c16ecbc5c2
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124234 (2015)
Emerging evidence suggests that the vascular endothelial growth factor receptor 2 (VEGFR2) and protein kinase D1 (PKD1) signaling axis plays a critical role in normal and pathological angiogenesis and inflammation related processes. Despite all effor
Externí odkaz:
https://doaj.org/article/e59f67d585014cf3805d900a5d2cab4d
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97868 (2014)
Lipotoxicity refers to cellular dysfunctions caused by elevated free fatty acid levels playing a central role in the development and progression of obesity related diseases. Saturated fatty acids cause insulin resistance and reduce insulin production
Externí odkaz:
https://doaj.org/article/4924eb840963410290f474ed9a447ace
Autor:
Vassilis Mavromatidis, Zoltan Varga, Frigyes Waczek, Zoltán Őrfi, László Őrfi, György Kéri, George Mosialos
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95688 (2014)
Epstein-Barr virus (EBV) is a human herpesvirus, which is causally associated with the development of several B lymphocytic malignancies that include Burkitt's lymphomas, Hodgkin's disease, AIDS and posttransplant associated lymphomas. The transformi
Externí odkaz:
https://doaj.org/article/e12914d92de047f4873a5f54d353315e
Autor:
Henrik Daub, Josef Wissing, György Kéri, Matt Cotten, Bert Klebl, Stefan Müller, Martina Weber, Alexander Kurtenbach, Stephanie Blencke, Klaus Godl, Zoltán Greff, Dirk Brehmer
Supplementary Methods and Figure from Cellular Targets of Gefitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c7a36d033024c906dd8d464db7ab66
https://doi.org/10.1158/0008-5472.22361673.v1
https://doi.org/10.1158/0008-5472.22361673.v1
Autor:
Henrik Daub, Josef Wissing, György Kéri, Matt Cotten, Bert Klebl, Stefan Müller, Martina Weber, Alexander Kurtenbach, Stephanie Blencke, Klaus Godl, Zoltán Greff, Dirk Brehmer
Supplementary Table 2 from Cellular Targets of Gefitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fef01c4943db660c7fa2c6553b62f51
https://doi.org/10.1158/0008-5472.22333051.v1
https://doi.org/10.1158/0008-5472.22333051.v1
Autor:
Axel Ullrich, György Kéri, Henrik Daub, István Szabadkai, László Őrfi, Yuri P. Knyazev, Kirti Sharma, Yuri V. Cheburkin, Peter G. Knyazev, Yi-Xiang Zhang
Supplementary Table 1 from AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69242eef7a4abffe5f9f345eac010ab4
https://doi.org/10.1158/0008-5472.22375325
https://doi.org/10.1158/0008-5472.22375325