Zobrazeno 1 - 10
of 21
pro vyhledávání: '"György Hutvàgner"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Glioblastoma is one of the most common and aggressive brain tumors and has seen few improvements in patient outcomes. Inter-tumor heterogeneity between tumors of different patients as well as intra-tumor heterogeneity of cells within the sam
Externí odkaz:
https://doaj.org/article/f3fea32984e4428bb8c77a8f8df02538
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Pediatric solid tumors are a diverse group of extracranial solid tumors representing approximately 40% of childhood cancers. Pediatric solid tumors are believed to arise as a result of disruptions in the developmental process of precursor cells which
Externí odkaz:
https://doaj.org/article/3cdb700c3854492985b5f18023003841
Autor:
Jennifer E. Cropley, Sally A. Eaton, Alastair Aiken, Paul E. Young, Eleni Giannoulatou, Joshua W.K. Ho, Michael E. Buckland, Simon P. Keam, Gyorgy Hutvagner, David T. Humphreys, Katherine G. Langley, Darren C. Henstridge, David I.K. Martin, Mark A. Febbraio, Catherine M. Suter
Publikováno v:
Molecular Metabolism, Vol 5, Iss 8, Pp 699-708 (2016)
Objective: Parental obesity can induce metabolic phenotypes in offspring independent of the inherited DNA sequence. Here we asked whether such non-genetic acquired metabolic traits can be passed on to a second generation that has never been exposed t
Externí odkaz:
https://doaj.org/article/e750315967c34129a01c1104d440a993
Autor:
Simon P. Keam, Gyorgy Hutvagner
Publikováno v:
Life, Vol 5, Iss 4, Pp 1638-1651 (2015)
This review will summarise the recent discoveries and current state of research on short noncoding RNAs derived from tRNAs—known as tRNA-derived fragments (tRFs). It will describe the features of the known subtypes of these RNAs; including sequence
Externí odkaz:
https://doaj.org/article/80dcc2b043494dd0a70a0a4add4295d0
Publikováno v:
Cancers, Vol 12, Iss 8, p 2198 (2020)
Adrenocortical Carcinoma (ACC) is a rare but aggressive malignancy with poor prognosis and limited response to available systemic therapies. Although complete surgical resection gives the best chance for long-term survival, ACC has a two-year recurre
Externí odkaz:
https://doaj.org/article/deabc83c05ab4cf2946ab55c36c68a68
Autor:
Judit Remenyi, Mirjam W M van den Bosch, Oleg Palygin, Rajen B Mistry, Colin McKenzie, Andrew Macdonald, Gyorgy Hutvagner, J Simon C Arthur, Bruno G Frenguelli, Yuriy Pankratov
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62509 (2013)
miR-132 and miR-212 are two closely related miRNAs encoded in the same intron of a small non-coding gene, which have been suggested to play roles in both immune and neuronal function. We describe here the generation and initial characterisation of a
Externí odkaz:
https://doaj.org/article/109d47346eba47aea53f44d1ee754789
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33144 (2012)
MiRNAs can regulate gene expression through versatile mechanisms that result in increased or decreased expression of the targeted mRNA and it could effect the expression of thousands of protein in a particular cell. An increasing body of evidence sug
Externí odkaz:
https://doaj.org/article/843924bf49674c7f8e42cc0c71334745
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 1, p 31 (2015)
microRNAs (miRNAs) are short ~22 nucleotides (nt) ribonucleic acids which post-transcriptionally regulate gene expression. miRNAs are key regulators of all cellular processes, and the correct expression of miRNAs in an organism is crucial for proper
Externí odkaz:
https://doaj.org/article/d85724d937034a8fa4418682e5d1c735
Autor:
Daniel Hain, Brian R Bettencourt, Katsutomo Okamura, Tibor Csorba, Wibke Meyer, Zhigang Jin, Jason Biggerstaff, Haruhiko Siomi, Gyorgy Hutvagner, Eric C Lai, Michael Welte, H-Arno J Müller
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15264 (2010)
The Drosophila argonaute2 (ago2) gene plays a major role in siRNA mediated RNA silencing pathways. Unlike mammalian Argonaute proteins, the Drosophila protein has an unusual amino-terminal domain made up largely of multiple copies of glutamine-rich r
Externí odkaz:
https://doaj.org/article/0d5323b042cb4205832a6af6b21fe38b
Autor:
Yavor Hadzhiev, Haseeb K. Qureshi, Lucy Wheatley, Ledean Cooper, Aleksandra Jasiulewicz, Huy Van Nguyen, Joseph W. Wragg, Divyasree Poovathumkadavil, Sascha Conic, Sarah Bajan, Attila Sik, György Hutvàgner, Làszlò Tora, Agnieszka Gambus, John S. Fossey, Ferenc Müller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Transcription is globally repressed in early stage of embryo development, but a set of genes including pri-miR-430 and zinc finger genes is known to escape the repression. Here the authors image the very first transcriptional activities in the living
Externí odkaz:
https://doaj.org/article/c687a4f0c35544f7aae2b16326e305e8