Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Gwyndolen Harburg"'
Autor:
Gwyndolen Harburg, Jennifer Compton, Wei Liu, Naomi Iwai, Shahrzad Zada, Rebecca Marlow, Phyllis Strickland, Yi Arial Zeng, Lindsay Hinck
Publikováno v:
Stem Cell Reports, Vol 3, Iss 3, Pp 385-393 (2014)
WNT signaling stimulates the self-renewal of many types of adult stem cells, including mammary stem cells (MaSCs), but mechanisms that limit this activity are poorly understood. Here, we demonstrate that SLIT2 restricts stem cell renewal by signaling
Externí odkaz:
https://doaj.org/article/1259f5beb3c14a56988bd0fb05d79744
Autor:
Gwyndolen Harburg, Oscar Cazares, J W Bubolz, Pinky Lee, Catherine J. Strietzel, Lindsay Hinck, Jon Howard, Sharmila Chatterjee, Jeremy R. Sanford, Sol Katzman
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
In the mammary gland, how alveolar progenitor cells are recruited to fuel tissue growth with each estrus cycle and pregnancy remains poorly understood. Here, we identify a regulatory pathway that controls alveolar progenitor differentiation and lacta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648fbedbe3862dc22789bee665fb0993
http://europepmc.org/articles/PMC8627605
http://europepmc.org/articles/PMC8627605
Autor:
Shahrzad Zada, Lindsay Hinck, Rebecca Marlow, Jennifer E. Compton, Naomi Iwai, Yi Arial Zeng, Wei Liu, Gwyndolen Harburg, Phyllis Strickland
Publikováno v:
Stem Cell Reports, Vol 3, Iss 3, Pp 385-393 (2014)
Stem Cell Reports
Stem cell reports, vol 3, iss 3
Harburg, G; Compton, J; Liu, W; Iwai, N; Zada, S; Marlow, R; et al.(2014). SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling. Stem Cell Reports, 3(3), 385-393. doi: 10.1016/j.stemcr.2014.07.007. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/6p50215s
Harburg, G; Compton, J; Liu, W; Iwai, N; Zada, S; Marlow, R; et al.(2014). SLIT/ROBO2 signaling promotes mammary stem cell senescence by inhibiting wnt signaling. Stem Cell Reports, 3(3), 385-393. doi: 10.1016/j.stemcr.2014.07.007. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/84q569vd
Stem Cell Reports, vol 3, iss 3
Stem Cell Reports
Stem cell reports, vol 3, iss 3
Harburg, G; Compton, J; Liu, W; Iwai, N; Zada, S; Marlow, R; et al.(2014). SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling. Stem Cell Reports, 3(3), 385-393. doi: 10.1016/j.stemcr.2014.07.007. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/6p50215s
Harburg, G; Compton, J; Liu, W; Iwai, N; Zada, S; Marlow, R; et al.(2014). SLIT/ROBO2 signaling promotes mammary stem cell senescence by inhibiting wnt signaling. Stem Cell Reports, 3(3), 385-393. doi: 10.1016/j.stemcr.2014.07.007. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/84q569vd
Stem Cell Reports, vol 3, iss 3
Summary WNT signaling stimulates the self-renewal of many types of adult stem cells, including mammary stem cells (MaSCs), but mechanisms that limit this activity are poorly understood. Here, we demonstrate that SLIT2 restricts stem cell renewal by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442f4296e178a305ca2add7d3b6e6525
Autor:
John D. Miedler, Sylvia C. Hewitt, Monica M. Montano, Jonathan D. Mosley, Kristen L. Lozada, Klaus H. Kaestner, Jane E. Visvader, Fadi W. Abdul-Karim, Gina M. Bernardo, Andrew K. Godwin, Gwyndolen Harburg, Ruth A. Keri, Kenneth S. Korach
Publikováno v:
Development. 137:2045-2054
FOXA1, estrogen receptor alpha (ERalpha) and GATA3 independently predict favorable outcome in breast cancer patients, and their expression correlates with a differentiated, luminal tumor subtype. As transcription factors, each functions in the morpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa75d03854fcd810ee712a2ca90e29c1
https://doi.org/10.1242/dev.043299
https://doi.org/10.1242/dev.043299
Autor:
Gwyndolen Harburg, Masahiro Yamaguchi, Chitra D. Mandyam, Amelia J. Eisch, Amy A. Arguello, Joshua R. Schonborn
Publikováno v:
Neuroscience. 157:70-79
Opiates, such as morphine, decrease neurogenesis in the adult hippocampal subgranular zone (SGZ), raising the possibility that decreased neurogenesis contributes to opiate-induced cognitive deficits. However, there is an incomplete understanding of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a63cddf0fd552aa9d632081e5c47eec
https://doi.org/10.1016/j.neuroscience.2008.08.064
https://doi.org/10.1016/j.neuroscience.2008.08.064
Autor:
Bhupinder Pal, Toula Bouras, François Vaillant, Samantha R. Oakes, Geoffrey J. Lindeman, Jane E. Visvader, Gwyndolen Harburg, Marie Liesse Asselin-Labat
Publikováno v:
Cell Stem Cell. 3(4):429-441
SummaryThe recent identification of mouse mammary stem cells (MaSCs) and progenitor subpopulations has enhanced the prospect of investigating the genetic control of their lineage specification and differentiation. Here we have explored the role of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94d578e0c4f8774062e7fe92d77a3a0
Publikováno v:
Neuroscience. 146:108-122
Neurogenesis studies on the adult mouse hippocampal subgranular zone (SGZ) typically report increases or decreases in proliferation. However, key information is lacking about these proliferating SGZ precursors, from the fundamental--what dose of brom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df6a865df23e8d8c432b82d67245f68
https://doi.org/10.1016/j.neuroscience.2006.12.064
https://doi.org/10.1016/j.neuroscience.2006.12.064
Autor:
Amelia J. Eisch, Gwyndolen Harburg
Publikováno v:
Hippocampus. 16:271-286
Once thought to produce global, nonspecific brain injury, drugs of abuse are now known to produce selective neuro-adaptations in particular brain regions. These neuro-adaptations are being closely examined for clues to the development, maintenance, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9705ad3c2fd2aff4562d8d1a4e4760
https://doi.org/10.1002/hipo.20161
https://doi.org/10.1002/hipo.20161
Autor:
Hector Macias, Yazeed Samara, Angel Moran, Jennifer E. Compton, Phyllis Strickland, Gwyndolen Harburg, Lindsay Hinck, Melissa Moreno
Publikováno v:
Developmental cell. 20(6)
SummaryIn the field of breast biology, there is a growing appreciation for the “gatekeeping function” of basal cells during development and disease processes yet mechanisms regulating the generation of these cells are poorly understood. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86825f422a03fcc0937163d74cf86d05
https://pubmed.ncbi.nlm.nih.gov/21664580
https://pubmed.ncbi.nlm.nih.gov/21664580
Recent evidence suggests that mu opioid receptors (MOR) are key regulators of hippocampal structure and function. For example, exogenous MOR agonists morphine and heroin negatively impact hippocampal function and decrease adult hippocampal neurogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffbb355abc4a82e49765a0bf20ae903
https://europepmc.org/articles/PMC2230097/
https://europepmc.org/articles/PMC2230097/
