Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Gwo‐Ching Sun"'
Publikováno v:
Physiological Reports, Vol 12, Iss 7, Pp n/a-n/a (2024)
Abstract Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) are rapidly gaining ground in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and acute myocardial infarction (AMI) by an unknown mechanism. Upregulation of Na+/
Externí odkaz:
https://doaj.org/article/6d2bb96610a247ef999a156948b8d728
Publikováno v:
Korean Journal of Anesthesiology, Vol 75, Iss 5, Pp 453-455 (2022)
Externí odkaz:
https://doaj.org/article/f5b4bb9133f7433a947fa2a551801c23
Autor:
Chiu-Yi Ho, Yu-Te Lin, Hsin-Hung Chen, Wen-Yu Ho, Gwo-Ching Sun, Michael Hsiao, Pei-Jung Lu, Pei-Wen Cheng, Ching-Jiunn Tseng
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Inflammation is a common pathophysiological trait found in both hypertension and cardiac vascular disease. Recent evidence indicates that fractalkine (FKN) and its receptor CX3CR1 have been linked to inflammatory response in the b
Externí odkaz:
https://doaj.org/article/ddefea7ce1bc4134b9612afa424c3dcf
Autor:
Ying-Ying Chen, Tsung-Tien Wu, Chiu-Yi Ho, Tung-Chen Yeh, Gwo-Ching Sun, Ching-Jiunn Tseng, Pei-Wen Cheng
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7142 (2022)
Chronic hyperglycemia triggers an abnormal rise in reactive oxygen species (ROS) that leads to blindness in patients with diabetes mellitus (DM) and cataracts. In this study, the effects of dapagliflozin, metformin and resveratrol on ROS production w
Externí odkaz:
https://doaj.org/article/bbdb503ec9ff48d293a683bc6738ecc4
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1784 (2021)
Opioids, a kind of peptide hormone involved in the development of hypertension, cause systemic and cerebral inflammation, and affects regions of the brain that are important for blood pressure (BP) control. A cause-and-effect relationship exists betw
Externí odkaz:
https://doaj.org/article/deb1e3ed2ce64487b8887dc3d3e167af
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1650 (2021)
Traumatic brain injury confers a significant and growing public health burden. It is a major environmental risk factor for dementia. Nonetheless, the mechanism by which primary mechanical injury leads to neurodegeneration and an increased risk of dem
Externí odkaz:
https://doaj.org/article/e89258d1c66c49afb00856c2bb208c1a
Autor:
Tsung-Tien Wu, Ying-Ying Chen, Chiu-Yi Ho, Tung-Chen Yeh, Gwo-Ching Sun, Ching-Jiunn Tseng, Pei-Wen Cheng
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1086 (2021)
Studies demonstrated that the receptor of advanced glycation end products (RAGE) induced epithelial-mesenchymal transition (EMT) formation in the lens epithelial cells (LECs) of diabetic cataracts. This work investigated how 3H-1,2-dithiole-3-thione
Externí odkaz:
https://doaj.org/article/a61ac09cd52543329ad92f3191ce10ac
Autor:
Chi-Cheng Lai, Wang-Chuan Juang, Gwo-Ching Sun, Yu-Kai Tseng, Rong-Chang Jhong, Ching-Jiunn Tseng, Tzyy-Yue Wong, Pei-Wen Cheng
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2196 (2020)
Vitamin D is associated with cardiovascular health through activating the vitamin D receptor that targets genes related to cardiovascular disease (CVD). The human cardiac microvascular endothelial cells (HCMECs) were used to develop mechanically and
Externí odkaz:
https://doaj.org/article/afc357c94c7b41129437d51fc1cdbbd8
Autor:
Ying-Ying Chen, Tsung-Tien Wu, Chiu-Yi Ho, Tung-Chen Yeh, Gwo-Ching Sun, Ya-Hsin Kung, Tzyy-Yue Wong, Ching-Jiunn Tseng, Pei-Wen Cheng
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4357 (2019)
Purpose: Cataracts in patients with diabetes mellitus (DM) are a major cause of blindness in developed and developing countries. This study aims to examine whether the generation of reactive oxygen species (ROS) via the increased expression of glucos
Externí odkaz:
https://doaj.org/article/cb86d92d20224690bed41889cf3c22cb
Autor:
Tzyy-Yue Wong, Sheng-Nan Chang, Rong-Chang Jhong, Ching-Jiunn Tseng, Gwo-Ching Sun, Pei-Wen Cheng
Publikováno v:
Cells, Vol 8, Iss 9, p 942 (2019)
Mechanics in the human body are required for normal cell function at a molecular level. It is now clear that mechanical stimulations play significant roles in cell growth, differentiation, and migration in normal and diseased cells. Recent studies ha
Externí odkaz:
https://doaj.org/article/cc412280c4c949f4993bb965b5b1f301