Kinetics of monocyte subpopulations during experimental cerebral malaria and its resolution in a model of late chloroquine treatment

Autor: Jade Royo, Aissata Camara, Benedicte Bertrand, Philippe Batigne, Agnes Coste, Bernard Pipy, Agnes Aubouy, the NeuroCM Group, Dissou Affolabi, Jules Alao, Daniel Ajzenberg, Linda Ayédadjou, Gwladys Bertin, Bibiane Biokou, Farid Boumédiène, Josselin Brisset, Michel Cot, Jean-Eudes Degbelo, Philippe Deloron, Ida Dossou-Dagba, Latifou Dramane, Jean François Faucher, Sandrine Houzé, Sayeh Jafari-Guemouri, Claire Kamaliddin, Elisée Kinkpé, Anaïs Labrunie, Yélé Ladipo, Thomas Lathiere, Achille Massougbodji, Audrey Mowendabeka, Jade Papin, Pierre-Marie Preux, Marie Raymondeau, Darius Sossou, Brigitte Techer, Bertin Vianou, Laurence Watier

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Cerebral malaria (CM) is one of the most severe forms of malaria and is a neuropathology that can lead to death. Monocytes have been shown to accumulate in the brain microvasculature at the onset of neurological symptoms during CM. Monocytes have a r

Externí odkaz: https://doaj.org/article/4f5964587e9a42c1a7d4d837a52404ac

Towards the rational design of a candidate vaccine against pregnancy associated malaria: conserved sequences of the DBL6epsilon domain of VAR2CSA.

Autor: Cyril Badaut, Gwladys Bertin, Tatiana Rustico, Nadine Fievet, Achille Massougbodji, Alioune Gaye, Philippe Deloron

Publikováno v: PLoS ONE, Vol 5, Iss 6, p e11276 (2010)

BackgroundPlacental malaria is a disease linked to the sequestration of Plasmodium falciparum infected red blood cells (IRBC) in the placenta, leading to reduced materno-fetal exchanges and to local inflammation. One of the virulence factors of P. fa

Externí odkaz: https://doaj.org/article/e3b3c3efef9d4b77a6be86d0a493125c

From genomic to LC-MS/MS evidence

Autor: Sayeh Guemouri, Sem Ezinmegnon, Romain Coppée, François Guillonneau, Claire Kamaliddin, Céline Peirera, Jade Royo, Philippe Deloron, Cédric Broussard, Stéphanie Huguet, Agnès Aubouy, Jules Alao, Emilie Guillochon, David Rombaut, Gino Agbota, Gwladys Bertin

Publikováno v: PLoS ONE
Plos One 6 (14), 1-14. (2019)
PLoS ONE, 2019, 14 (6), pp.e0218012. ⟨10.1371/journal.pone.0218012⟩
PLoS ONE, Public Library of Science, 2019, 14 (6), pp.e0218012. ⟨10.1371/journal.pone.0218012⟩
PLoS ONE, Vol 14, Iss 6, p e0218012 (2019)

International audience; Background PfEMP1 is the major protein from parasitic origin involved in the pathophysiology of severe malaria, and PfEMP1 domain subtypes are associated with the infection outcome. In addition, PfEMP1 variability is endless a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05416d50b6138899ab45164b340e4e5e
http://europepmc.org/articles/PMC6599223

Genomic from Plasmodium falciparum field isolates from Benin allows the identification of PfEMP1 variants by LC-MS/MS at the patient’s level

Autor: Rombaut D, Gwladys Bertin, Peirera C, Guemouri S, François Guillonneau, Philippe Deloron, Jules Alao, Stéphanie Huguet, Agnès Aubouy, Sem Ezinmegnon, Claire Kamaliddin, Emilie Guillochon, Cédric Broussard, Jade Royo

PfEMP1 are the major protein family from parasitic origin involves in the pathophysiology of severe malaria, and PfEMP1 domain subtypes are associated with the infection outcome. In addition, PfEMP1 variability in endless and current protein reposito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3a08857315d7a58a0fc826990c7d30

Prevalence of malaria in pregnancy in southern Laos: a cross-sectional survey

Autor: Keobouphaphone Chindavongsa, Nadine Fievet, Valérie Briand, Sandrine Houzé, Sommay Keomany, Nanthasane Vannavong, Mayfong Mayxay, Yom Inthavong, Paul N. Newton, Bouasy Hongvanthong, Jean-Yves Le Hesran, Gwladys Bertin

Publikováno v: Malaria Journal

Background There are no data on the burden of malaria in pregnancy (MiP) in Laos, where malaria still remains prevalent in the south. Methods Two cross-sectional surveys were conducted in 2014 to assess the prevalence of MiP in Vapi District, Salavan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837e98770fe6ae49f0460e5dcc124f03
https://pubmed.ncbi.nlm.nih.gov/27566274