Výsledky vyhledávání - "Gwilym J. Thompson"

Akademický článek

Estimating outcomes and cost effectiveness using a single-arm clinical trial: ofatumumab for double-refractory chronic lymphocytic leukemia

Autor: Anthony J. Hatswell, Gwilym J. Thompson, Penny A. Maroudas, Oleg Sofrygin, Thomas E. Delea

Publikováno v: Cost Effectiveness and Resource Allocation, Vol 15, Iss 1, Pp 1-8 (2017)

Abstract Background Ofatumumab (Arzerra®, Novartis) is a treatment for chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab [double refractory (DR-CLL)]. Ofatumumab was licensed on the basis of an uncontrolled Phase II study, Hx-CD

Externí odkaz: https://doaj.org/article/550ce4ac781d4fb8a5b2bd2611273f66

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Treatment practices in adults with chronic immune thrombocytopenia â a European perspective

Autor: Gwilym J. Thompson, Juan Besalduch, Drew Provan, Marc Michel, Francesco Rodeghiero, Kelly M. Grotzinger

Publikováno v: European Journal of Haematology. 84:160-168

Immune thrombocytopenia (ITP) is characterised by platelet destruction and impaired production leading to isolated thrombocytopenia. The aim of this study, comprising a retrospective longitudinal cohort study complemented by a Delphi panel of 35 phys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e57a60dc07684610c9ad83c3c2bec85
https://doi.org/10.1111/j.1600-0609.2009.01361.x

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Fluorescence-guided transurethral resection of bladder cancer using hexaminolevulinate: analysis of health economic impact in Sweden

Autor: Helen Durrant, Gwilym J Thompson, Hans Hedelin, Yngvil Kloster Thomas, Jim Furniss, Per-Uno Malmström

Publikováno v: Scandinavian Journal of Urology and Nephrology. 43:192-198

OBJECTIVE: A decision analytic model was established to estimate the budget impact on the Swedish health service of using hexaminolevulinate (HAL) in conjunction with white light cystoscopy (WLC) in the management of bladder cancer for 1 year followi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd696bd6dafbbfdfea1326dd8e54f44
https://doi.org/10.1080/00365590902808541

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Elevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release

Autor: Gwilym J. THOMPSON, Claudia LANGLAIS, Kelvin CAIN, Edward C. CONLEY, Gerald M. COHEN

Publikováno v: Biochemical Journal. 357:137-145

Efflux of intracellular K+ and cell shrinkage are features of apoptosis in many experimental systems, and a regulatory role has been proposed for cytoplasmic [K+] in initiating apoptosis. We have investigated this in both death-receptor-mediated and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::995efe421cdbb7dff039f22c91b225e5
https://doi.org/10.1042/bj3570137

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What Is Known about the Clinical and Economic Burden of Refractory Chronic Lymphocytic Leukemia in Clinical Practice: A Review of the Literature

Autor: Radek Wasiak, Vincent Levy, Gwilym J. Thompson, K Payne, Yvonne Lis

Publikováno v: Blood. 114:4549-4549

Abstract 4549 Introduction Chronic lymphocytic leukemia (CLL) is the most common adult haematological malignancy in the Western world. It remains incurable and follows an extremely variable clinical course with survival ranging from months to decades

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdb89ed51e4209d33b069669eb484dad
https://doi.org/10.1182/blood.v114.22.4549.4549

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