Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Gwenola Manic"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/b061004230974a23893ca6ec3c5c5af1
Autor:
Dmitriy Zamarin, Howard L Kaufman, Dobrin Draganov, Sofia R Gameiro, Ilio Vitale, Sandy Adjemian, Aitziber Buqué Martinez, Timothy A Chan, Richard L Edelson, Lucia Gabriele, Encouse Golden, Kevin J Harrington, Dewan Md Sakib Hossain, Michael Karin, Juan Jose Lasarte, Sherene Loi, Gwenola Manic, Alan A Melcher, Karen L Mossman, Maria Rescigno, Chiara Riganti, Antonella Sistigu, Bryan E Strauss, Kazuki Tatsuno, Stefaan W van Gool, Peter Vandenabeele
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/988b876661a144ee942a8a790aa6a723
Autor:
Dmitriy Zamarin, Howard L Kaufman, Dobrin Draganov, Sofia R Gameiro, Ilio Vitale, Sandy Adjemian, Aitziber Buqué Martinez, Timothy A Chan, Richard L Edelson, Lucia Gabriele, Encouse Golden, Kevin J Harrington, Dewan Md Sakib Hossain, Michael Karin, Juan Jose Lasarte, Sherene Loi, Gwenola Manic, Alan A Melcher, Karen L Mossman, Maria Rescigno, Chiara Riganti, Antonella Sistigu, Bryan E Strauss, Kazuki Tatsuno, Stefaan W van Gool, Peter Vandenabeele
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenviro
Externí odkaz:
https://doaj.org/article/a9d90895f1e544d9989ad2cde51f79c0
Autor:
Luca Mattiello, Sara Soliman Abdel Rehim, Martina Musella, Antonella Sistigu, Andrea Guarracino, Sara Vitale, Francesca Corradi, Claudia Galassi, Francesca Sperati, Gwenola Manic, Ruggero De Maria, Ilio Vitale
Publikováno v:
Cancers, Vol 13, Iss 8, p 1957 (2021)
Cancer stem cells (CSCs) drive not only tumor initiation and expansion, but also therapeutic resistance and tumor relapse. Therefore, CSC eradication is required for effective cancer therapy. In preclinical models, CSCs demonstrated high capability t
Externí odkaz:
https://doaj.org/article/243588b267864c5fabf92ef42fb2e44c
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 3 (2017)
Mitotic catastrophe is an oncosuppressive mechanism that targets cells experiencing defective mitoses via the activation of specific cell cycle checkpoints, regulated cell death pathways and/or cell senescence. This prevents the accumulation of karyo
Externí odkaz:
https://doaj.org/article/49ec480e6e66465e960ab55bdb09990f
Publikováno v:
OncoImmunology, Vol 6, Iss 5 (2017)
If there is a great new hope in the treatment of cancer, the immune system is it. Innate and adaptive immunity either promote or attenuate tumorigenesis and so can have opposing effects on the therapeutic outcome. Originally described as potent antiv
Externí odkaz:
https://doaj.org/article/366ebe8c600e4651a324b9e83793f59f
Autor:
Gwenola Manic, Aurélie Maurin-Marlin, Fanny Laurent, Ilio Vitale, Sylvain Thierry, Olivier Delelis, Philippe Dessen, Michelle Vincendeau, Christine Leib-Mösch, Uriel Hazan, Jean-François Mouscadet, Stéphanie Bury-Moné
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69691 (2013)
Ku, a cellular complex required for human cell survival and involved in double strand break DNA repair and multiple other cellular processes, may modulate retroviral multiplication, although the precise mechanism through which it acts is still contro
Externí odkaz:
https://doaj.org/article/3b232a1968ae45008281de4a164029d6
Autor:
Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frédéric Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, José R Regueiro, Hugues de Thé, Marie-Lise Gougeon, Mauro Piacentini, Guido Kroemer
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2458 (2008)
DNA damage can activate the oncosuppressor protein ataxia telangiectasia mutated (ATM), which phosphorylates the histone H2AX within characteristic DNA damage foci. Here, we show that ATM undergoes an activating phosphorylation in syncytia elicited b
Externí odkaz:
https://doaj.org/article/15997d8a8c2b4aaeb617c9750ec6c13c
Autor:
Martina Musella, Andrea Guarracino, Nicoletta Manduca, Claudia Galassi, Eliana Ruggiero, Alessia Potenza, Ester Maccafeo, Gwenola Manic, Luca Mattiello, Sara Soliman Abdel Rehim, Michele Signore, Marco Pietrosanto, Manuela Helmer-Citterich, Matteo Pallocca, Maurizio Fanciulli, Tiziana Bruno, Francesca De Nicola, Giacomo Corleone, Anna Di Benedetto, Cristiana Ercolani, Edoardo Pescarmona, Laura Pizzuti, Francesco Guidi, Francesca Sperati, Sara Vitale, Daniele Macchia, Massimo Spada, Giovanna Schiavoni, Fabrizio Mattei, Adele De Ninno, Luca Businaro, Valeria Lucarini, Laura Bracci, Eleonora Aricò, Giovanna Ziccheddu, Francesco Facchiano, Stefania Rossi, Massimo Sanchez, Alessandra Boe, Mauro Biffoni, Ruggero De Maria, Ilio Vitale, Antonella Sistigu
Publikováno v:
Nature Immunology. 23:1379-1392
Cancer stem cells (CSCs) are a subpopulation of cancer cells endowed with high tumorigenic, chemoresistant and metastatic potential. Nongenetic mechanisms of acquired resistance are increasingly being discovered, but molecular insights into the evolu
Publikováno v:
Trends in genetics : TIG. 38(8)
Unscheduled tetraploidy is a metastable state that rapidly evolves into aneuploidy. Recent findings reported by Gemble et al. demonstrate that freshly formed tetraploid cells fail to accumulate the required amounts of DNA replication factors during t