Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Gwenny M Verstappen"'
Autor:
Suzanne Arends, Frans G M Kroese, Arjan Vissink, Hendrika Bootsma, Gwenny M Verstappen, Liseth de Wolff, Annie Visser, Yannick van Sleen, Hella-Marie Heiermann, Janneke H Terpstra, Dimitri A Diavatopoulos, Marieke van der Heiden, Debbie van Baarle
Publikováno v:
RMD Open, Vol 8, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/7e22ce1fb96a4259bbebb1a661ca4a0b
Autor:
Hendrika Bootsma, Johanna Westra, Karina de Leeuw, Juan J. Fierro, Jelmer R. Prins, Gwenny M. Verstappen
Publikováno v:
RMD Open, Vol 9, Iss 3 (2023)
Objective To identify preconception clinical factors associated with adverse pregnancy outcomes (APO) in patients with systemic lupus erythematosus (SLE) or primary Sjögren’s syndrome (pSS).Methods A single-centre, retrospective cohort study was c
Externí odkaz:
https://doaj.org/article/8da19a1819da4e8089fd9e05ce39ce19
Autor:
Gwenny M. Verstappen, Lu Gao, Sarah Pringle, Erlin A. Haacke, Bert van der Vegt, Silvia C. Liefers, Vishal Patel, Yanhua Hu, Sumanta Mukherjee, Julie Carman, Laurence C. Menard, Frederik K. L. Spijkervet, Arjan Vissink, Hendrika Bootsma, Frans G. M. Kroese
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundWhile all salivary glands (SGs) can be involved in primary Sjögren’s syndrome (pSS), their respective role in pathogenesis remains unclear. Our objective was to assess immunopathway activation in paired parotid and labial gland tissue fr
Externí odkaz:
https://doaj.org/article/f633d64c90d94a9891b4cb74558cbd90
Autor:
Rick Wilbrink, Anneke Spoorenberg, Suzanne Arends, Kornelis S. M. van der Geest, Elisabeth Brouwer, Hendrika Bootsma, Frans G. M. Kroese, Gwenny M. Verstappen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B-cells have received little attention in axial spondyloarthritis (axSpA) and for this reason their role in pathogenesis remains unclear. However, there are indications that B-cells may be involved in the disease process. Our objective was to obtain
Externí odkaz:
https://doaj.org/article/45b1be5828094327b32925bfaa910762
Autor:
Johanna A. A. Bult, Jessica R. Plaça, Erlin A. Haacke, M. Martijn Terpstra, Gwenny M. Verstappen, Frederik K. L. Spijkervet, Frans G. M. Kroese, Wouter J. Plattel, Joost S. P. Vermaat, Hendrika Bootsma, Bert van der Vegt, Arjan Diepstra, Anke van den Berg, Klaas Kok, Marcel Nijland
Publikováno v:
Cancers, Vol 14, Iss 4, p 1010 (2022)
Patients with primary Sjogren’s syndrome (pSS) are at risk of developing extranodal marginal zone lymphoma (ENMZL) of the mucosa-associated lymphoid tissue (MALT) in the parotid glands. Unlike recurrent genomic aberrations observed in MALT lymphoma
Externí odkaz:
https://doaj.org/article/4fd386f22eed4b2682e771196f9fe967
Autor:
Tobit D. Steinmetz, Liseth de Wolff, Janneke H. Terpstra, Annie Visser, Hendrika Bootsma, Frans G.M. Kroese, Gwenny M. Verstappen
Publikováno v:
Clinical and Experimental Rheumatology, 40(12), 2338-2343. CLINICAL & EXPER RHEUMATOLOGY
Objective The peripheral lymphocyte compartment of patients with primary Sjögren’s syndrome (pSS) differs strongly from healthy individuals. Whether this altered lymphocyte composition also changes abnormally during immune reactions, especially by
Autor:
Liseth de Wolff, Suzanne Arends, Arjan Vissink, Gwenny M Verstappen, Frans G. M. Kroese, Hendrika Bootsma
Publikováno v:
Annals of the Rheumatic Diseases. 82(6)
We read with interest the correspondence related to the article ‘Interleukin 6 receptor inhibition in primary Sjogren syndrome: a multicentre double-blind randomised placebo-controlled trial’ in which possible explanations for negative findings i
Autor:
Roeland F. Prak, Suzanne Arends, Gwenny M. Verstappen, Greetje van Zuiden, Frans G.M. Kroese, Hendrika Bootsma, Inge Zijdewind
Publikováno v:
Clinical and Experimental Rheumatology, 40(12), 2318-2328. CLINICAL & EXPER RHEUMATOLOGY
OBJECTIVES: Fatigue is a major complaint in primary Sjögren's syndrome (pSS). To acquire a better understanding of fatigue in pSS, we investigated objective measures of performance decline (performance fatigability). Furthermore, we evaluated the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0b9ab79777a6391e480a8662ad38e1
https://research.rug.nl/en/publications/d37f20a8-8266-416a-ac4d-ee2f84c3f746
https://research.rug.nl/en/publications/d37f20a8-8266-416a-ac4d-ee2f84c3f746
Autor:
Tobit D, Steinmetz, Gwenny M, Verstappen, Sebastian R, Schulz, Liseth, de Wolff, Rick, Wilbrink, Annie, Visser, Janneke, Terpstra, Hendrika, Bootsma, Frans G M, Kroese
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
B cell hyperactivity plays an important role in primary Sjögren's syndrome (pSS). To better understand the B cell effector branch, namely antibody-secreting cells (ASC; plasmablasts and plasma cells) in pSS, this study examines abundance, maturation
Autor:
Richard J Bende, Linda M Slot, Mark J Kwakkenbos, Thera AM Wormhoudt, Aldo Jongejan, Gwenny M Verstappen, Antoine CM van Kampen, Jeroen EJ Guikema, Frans GM Kroese, Carel JM van Noesel
Publikováno v:
Journal of pathology. John Wiley and Sons Ltd
We recently demonstrated that normal memory B lymphocytes carry a substantial number of de novo mutations in the genome. Here, we performed exome-wide somatic mutation analyses of bona fide autoreactive rheumatoid factor (RF)-expressing memory B cell