Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Gwenn S Smith"'
Autor:
Adam P Spira, Christopher Yager, Jason Brandt, Gwenn S Smith, Yun Zhou, Anil Mathur, Anil Kumar, James R Brašić, Dean F Wong, Mark N Wu
Publikováno v:
SAGE Open Medicine, Vol 2 (2014)
Background/aims: Although disturbed sleep is associated with cognitive deficits, the association between sleep disturbance and Alzheimer’s disease pathology is unclear. In this pilot study, we examined the extent to which sleep duration, sleep qual
Externí odkaz:
https://doaj.org/article/3c37c59f3cda4fabb428ba0d66e26366
Autor:
Ana Sofía Ríos, Simón Oxenford, Clemens Neudorfer, Konstantin Butenko, Ningfei Li, Nanditha Rajamani, Alexandre Boutet, Gavin J. B. Elias, Jurgen Germann, Aaron Loh, Wissam Deeb, Fuyixue Wang, Kawin Setsompop, Bryan Salvato, Leonardo Brito de Almeida, Kelly D. Foote, Robert Amaral, Paul B. Rosenberg, David F. Tang-Wai, David A. Wolk, Anna D. Burke, Stephen Salloway, Marwan N. Sabbagh, M. Mallar Chakravarty, Gwenn S. Smith, Constantine G. Lyketsos, Michael S. Okun, William S. Anderson, Zoltan Mari, Francisco A. Ponce, Andres M. Lozano, Andreas Horn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Deep brain stimulation has been investigated as a potential treatment for cognitive impairments in Alzheimer’s disease. Here the authors carry out post hoc analysis of multi-center cohorts to investigate the anatomical and functional correlates of
Externí odkaz:
https://doaj.org/article/44042e8fc7c347909735b26f535f79b5
Autor:
Gwenn S. Smith, Hillary Protas, Hiroto Kuwabara, Alena Savonenko, Najlla Nassery, Neda F. Gould, Michael Kraut, Dimitri Avramopoulos, Daniel Holt, Robert F. Dannals, Ayon Nandi, Yi Su, Eric M. Reiman, Kewei Chen
Publikováno v:
NeuroImage: Clinical, Vol 37, Iss , Pp 103322- (2023)
Background: Degeneration of the serotonin system has been observed in Alzheimer’s disease (AD) and in mild cognitive impairment (MCI). In transgenic amyloid mouse models, serotonin degeneration is detected prior to widespread cortical beta-amyloid
Externí odkaz:
https://doaj.org/article/9f77b3ae48cb4778880522ffadcdb828
Autor:
Manoj K. Doss, Michal Považan, Monica D. Rosenberg, Nathan D. Sepeda, Alan K. Davis, Patrick H. Finan, Gwenn S. Smith, James J. Pekar, Peter B. Barker, Roland R. Griffiths, Frederick S. Barrett
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Psilocybin has shown promise for the treatment of mood disorders, which are often accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have proposed neuropsychoplastogenic effects as mechanisms underlying the end
Externí odkaz:
https://doaj.org/article/86a0e8c36d244f1fa71b11da3c3a46b2
Autor:
Gwenn S. Smith, Clifford I. Workman, Hillary Protas, Yi Su, Alena Savonenko, Hiroto Kuwabara, Neda F. Gould, Michael Kraut, Jin Hui Joo, Ayon Nandi, Dimitri Avramopoulos, Eric M. Reiman, Kewei Chen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Depression in late-life is associated with increased risk of cognitive decline and development of all-cause dementia. The neurobiology of late-life depression (LLD) may involve both neurochemical and neurodegenerative mechanisms that are com
Externí odkaz:
https://doaj.org/article/01ad391dea8843638cdd171ec1cb677d
Autor:
Frederick S. Barrett, Yun Zhou, Theresa M. Carbonaro, Joshua M. Roberts, Gwenn S. Smith, Roland R. Griffiths, Dean F. Wong
Publikováno v:
Frontiers in Neuroergonomics, Vol 2 (2022)
Psilocybin (a serotonin 2A, or 5-HT2A, receptor agonist) has shown preliminary efficacy as a treatment for mood and substance use disorders. The current report utilized positron emission tomography (PET) with the selective 5-HT2A receptor inverse ago
Externí odkaz:
https://doaj.org/article/51e17154b911429ab1634d10b127448d
Autor:
Nir Lipsman, Ying Meng, Allison J. Bethune, Yuexi Huang, Benjamin Lam, Mario Masellis, Nathan Herrmann, Chinthaka Heyn, Isabelle Aubert, Alexandre Boutet, Gwenn S. Smith, Kullervo Hynynen, Sandra E. Black
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Magnetic resonance-guided focused ultrasound with injected microbubbles has been used to temporarily open the blood–brain barrier (BBB) in animal models of Alzheimer's disease (AD). Here, the authors use this technology to non-invasively open the B
Externí odkaz:
https://doaj.org/article/032e903a864c4b94ba707f9db98faead
Autor:
Gwenn S. Smith, Frederick S. Barrett, Jin Hui Joo, Najlla Nassery, Alena Savonenko, Devin J. Sodums, Christopher M. Marano, Cynthia A. Munro, Jason Brandt, Michael A. Kraut, Yun Zhou, Dean F. Wong, Clifford I. Workman
Publikováno v:
Neurobiology of Disease, Vol 105, Iss , Pp 33-41 (2017)
Neuropathological and neuroimaging studies have consistently demonstrated degeneration of monoamine systems, especially the serotonin system, in normal aging and Alzheimer's disease. The evidence for degeneration of the serotonin system in mild cogni
Externí odkaz:
https://doaj.org/article/0b63d736d983476b8fe90556b66504a7
Autor:
Gwenn S, Smith
Publikováno v:
The American Journal of Geriatric Psychiatry. 30:1310-1312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf6cd5c0ff969c31b9d9b951e8ea152
https://doi.org/10.1016/j.jagp.2022.08.001
https://doi.org/10.1016/j.jagp.2022.08.001
Autor:
Gustavo C. Medeiros, Claire Twose, Alexandra Weller, John W. Dougherty, Fernando S. Goes, Haris I. Sair, Gwenn S. Smith, Durga Roy
Publikováno v:
Journal of Neurotrauma. 39:755-772
Depression is the most frequent neuropsychiatric complication after traumatic brain injury (TBI) and is associated with poorer outcomes. Neuroimaging has the potential to improve our understanding of the neural correlates of depression after TBI and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722234da6183fec43bf5a07b05bb9b7d
https://doi.org/10.1089/neu.2021.0374
https://doi.org/10.1089/neu.2021.0374