Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gwendolyn M. Wilmes"'
Autor:
Ethan Clark, Gwendolyn M Wilmes, Rachel S Quesenberry, Sergey V Shulga-Morskoy, Violetta Medik, Stuart W. Hicks, Megan E Lewis, Stephen R Lutz, Anthony B Cooper, Hugh H. Russell, Elizabeth E. Reczek, Paulina Kocjan, Jesse A Stevenson, Kimberly L Carey
Publikováno v:
mAbs
Antibody combination therapeutics (ACTs) are polyvalent biopharmaceuticals that are uniquely suited for the control of complex diseases, including antibiotic resistant infectious diseases, autoimmune disorders and cancers. However, ACTs also represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21b4b9f26ad2a6a895ed8b21f87f656
Autor:
Hannes Braberg, Gerard Cagney, Tracy L. Kress, Trey Ideker, Gregg B. Whitworth, Sean R. Collins, Jonathan S. Weissman, Christine Guthrie, Gwendolyn M. Wilmes, Sourav Bandyopadhyay, Michael Shales, Nevan J. Krogan, Megan Bergkessel
Publikováno v:
Molecular Cell. 32:735-746
We used a quantitative, high-density genetic interaction map, or E-MAP (Epistatic MiniArray Profile), to interrogate the relationships within and between RNA processing pathways. Due to their complexity, and the essential roles of many of the compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca138c4b5d6ba8035d22cf192940ad60
https://doi.org/10.1016/j.molcel.2008.11.012
https://doi.org/10.1016/j.molcel.2008.11.012
Autor:
Stephen P. Bell, Matthew D. Jacobson, Richard J. Austin, Vincent Archambault, Gwendolyn M. Wilmes, Frederick R. Cross
Publikováno v:
Genes & Development. 18:981-991
Cyclin-dependent kinases are critical regulators of eukaryotic DNA replication. We show that the S-phase cyclin Clb5 binds stably and directly to the origin recognition complex (ORC). This interaction is mediated by an “RXL” target sequence, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e85df04c9ebc60e13981a7199a07a73
https://doi.org/10.1101/gad.1202304
https://doi.org/10.1101/gad.1202304
Autor:
Stephen P. Bell, Gwendolyn M. Wilmes
Publikováno v:
Proceedings of the National Academy of Sciences. 99:101-106
The minimal requirements for a eukaryotic origin of replication are an initiator binding site and a region of helically unstable DNA [DNA unwinding element (DUE)]. Budding yeast origins consist of modular elements, and one of these elements, B2, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec178ba053f1b9c494ea88a62a9dace
https://doi.org/10.1073/pnas.012578499
https://doi.org/10.1073/pnas.012578499
Autor:
Samuel C. Wadsworth, Samantha F. Povlich, Gwendolyn M. Wilmes, K. Reed Clark, Christopher J. Morrison, Jonathan G. Mehtala
Publikováno v:
Molecular Therapy. 24:S122
The development and commercialization of a biological pharmaceutical, such as recombinant adeno associated virus (rAAV), requires rigorous quantitative and qualitative testing. An accurate particle titer measurement is important for the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce9b3da1dd874b4f0b6ded698ff9dba7
https://doi.org/10.1016/s1525-0016(16)33113-6
https://doi.org/10.1016/s1525-0016(16)33113-6
Autor:
Samuel C. Wadsworth, Christopher J. Morrison, Gwendolyn M. Wilmes, K. Reed Clark, Samantha F. Povlich, James D. Maratt
Publikováno v:
Molecular Therapy. 23:S267
The recent resurgence of using rAAV vectors as commercially viable therapeutic agents has highlighted the need to identify stable capsid/genomic construct combinations which can both endure a typical cGMP manufacturing process and possess a long prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8dab0b9722a83f0087f7f9d46f1bbb
https://doi.org/10.1016/s1525-0016(16)34279-4
https://doi.org/10.1016/s1525-0016(16)34279-4
Autor:
Vincent Archambault, Gwendolyn M. Wilmes, Frederick R. Cross, Matthew D. Jacobson, Nicolas E. Buchler
Publikováno v:
Cell cycle (Georgetown, Tex.). 4(1)
We recently reported that the ‘hydrophobic patch’ (HP) of the Saccharomyces cerevisiae S-phase cyclin Clb5 facilitates its interaction with Orc6 (via its Cy or RXL motif), providing a mechanism that helps prevent re-replication from individual or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9269bdffd76be2960f733b868968ecd
https://pubmed.ncbi.nlm.nih.gov/15611618
https://pubmed.ncbi.nlm.nih.gov/15611618
Autor:
Gwendolyn M. Wilmes, Christine Guthrie
Publikováno v:
Molecular Cell
Summary The yeast Sac3:Cdc31:Sus1:Thp1 (TREX-2) complex facilitates the repositioning and association of actively transcribing genes with nuclear pores (NPCs)—“gene gating”—that is central to integrating transcription, processing, and mRNA nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9bf59fb881815eeac6edba9e2d729b
Autor:
Wilmes, Gwendolyn M., Carey, Kimberly L., Hicks, Stuart W., Russell, Hugh H., Stevenson, Jesse A., Kocjan, Paulina, Lutz, Stephen R., Quesenberry, Rachel S., Shulga-Morskoy, Sergey V., Lewis, Megan E., Clark, Ethan, Medik, Violetta, Cooper, Anthony B., Reczek, Elizabeth E.
Publikováno v:
mAbs; Jul/Aug2014, Vol. 6 Issue 4, p957-967, 11p
Autor:
Wilmes, Gwendolyn Martha
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2004.
Includes bibliographical references.
This suggests that the S phase cyclin, which first activates DNA replication, then acts locally at the origin to prevent pr
Includes bibliographical references.
This suggests that the S phase cyclin, which first activates DNA replication, then acts locally at the origin to prevent pr
Externí odkaz:
http://hdl.handle.net/1721.1/28308
