Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gwendolyn I Humphreys"'
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111975 (2014)
17β-estradiol (E2) plays critical roles in a number of target tissues including the mammary gland, reproductive tract, bone, and brain. Although it is clear that E2 reduces inflammation and ischemia-induced damage in the cerebral cortex, the molecul
Externí odkaz:
https://doaj.org/article/de17d40398cd4becadd2ec12ff8b3a19
Publikováno v:
Molecular and Cellular Endocrinology. 406:19-26
Although estrogen receptor alpha (ERα) and 17β-estradiol play critical roles in protecting the cerebral cortex from ischemia-induced damage, there has been some controversy about the expression of ERα in this region of the brain. We have examined
Autor:
Sua Myong, David A. Ahlquist, Younghoon Kim, Gwendolyn I. Humphreys, William R. Taylor, Ann M. Nardulli, Rashid Bashir, Jiwook Shim, Farhad Kosari, George Vasmatzis
Publikováno v:
ACS Nano. 9:290-300
DNA methylation is an epigenetic modification of DNA in which methyl groups are added at the 5-carbon position of cytosine. Aberrant DNA methylation, which has been associated with carcinogenesis, can be assessed in various biological fluids and pote
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 138:410-420
While it is well established that 17β-estradiol (E2) protects the rodent brain from ischemia-induced damage, it has been unclear how this neuroprotective effect is mediated. Interestingly, convincing evidence has also demonstrated that maintaining o
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111975 (2014)
PLoS ONE
PLoS ONE
17β-estradiol (E2) plays critical roles in a number of target tissues including the mammary gland, reproductive tract, bone, and brain. Although it is clear that E2 reduces inflammation and ischemia-induced damage in the cerebral cortex, the molecul
Autor:
Chaitanya Sathe, Gwendolyn I. Humphreys, Farhad Kosari, Jan Marie Munz, Bala Murali Venkatesan, Xueqing Zou, Ann M. Nardulli, Jiwook Shim, George Vasmatzis, Rashid Bashir, Klaus Schulten
Publikováno v:
Scientific Reports
Epigenetic modifications in eukaryotic genomes occur primarily in the form of 5-methylcytosine (5 mC). These modifications are heavily involved in transcriptional repression, gene regulation, development and the progression of diseases including canc