Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gwendolyn A. Myers"'
Autor:
Inessa S. Levenbook, Kelly Scappaticci, Michael Knauber, Sunheang Shin, Robert A. Beck, John Catalan, Ken Draper, Thad Pullano, Chuck Miller, W. Tad Archambault, Gwendolyn A. Myers, Farshad Guirakhoo, Konstantin V. Pugachev, Thomas P. Monath, Zhenxi Zhang
Publikováno v:
Biologicals. 33:131-144
Current requirements for control of live viral vaccines, including yellow fever 17D, produced from potentially neurotropic wild-type viruses include tests for neurovirulence in nonhuman primates. We have used yellow fever 17D virus as a live vector f
Autor:
Simon Delagrave, Thomas P. Monath, B. Barrere, Zhenxi Zhang, Konstantin V. Pugachev, S. Cyrek, I. Levenbook, Nancy V. Brown, C. Fournier, Barbara W. Johnson, Jean Lang, Farshad Guirakhoo, Ken Draper, Richard A. Nichols, Gwendolyn A. Myers
Publikováno v:
Journal of Virology. 78:9998-10008
A chimeric yellow fever-dengue 1 (ChimeriVax-DEN1) virus was produced by the transfection of Vero cells with chimeric in vitro RNA transcripts. The cell culture supernatant was subjected to plaque purification for the identification of a vaccine cand
Autor:
Jeffrey S. Kennedy, Paul S. Blum, John Cruz, Konstantin V. Pugachev, Thomas P. Monath, Richard Nichols, Brie Coughlin, Gwendolyn A. Myers, Casey Johnson, Francis A. Ennis, Weltzin Richard A, Jian Liu
Publikováno v:
Nature Medicine. 9:1125-1130
Although the smallpox virus was eradicated over 20 years ago, its potential release through bioterrorism has generated renewed interest in vaccination. To develop a modern smallpox vaccine, we have adapted vaccinia virus that was derived from the exi
Autor:
Gwendolyn A. Myers, Inessa S. Levenbook, Robert E. Shope, Thomas J. Chambers, Juan Arroyo, Kenneth F. Soike, Thomas P. Monath, Simon Delagrave, Marion S. Ratterree, Zhenxi Zhang, Alan D.T. Barrett, Farshad Guirakhoo
Publikováno v:
Vaccine. 17:1869-1882
Yellow fever 17D virus, a safe and effective live, attenuated vaccine, was used as a vector for genes encoding the protective antigenic determinants of a heterologous member of the genus Flavivirus , Japanese encephalitis (JE) virus, the leading caus
Autor:
Thomas P. Monath, Cynthia K. Lee, Harold Kleanthous, John Nedrud, Richard A. Nichols, Gwendolyn A. Myers, Weltzin Richard A, Paul J. Giannasca, Thomas H. Ermak
Publikováno v:
The Journal of Experimental Medicine
We examined the roles of cell- and antibody-mediated immunity in urease vaccine–induced protection against Helicobacter pylori infection. Normal and knockout mice deficient in major histocompatibility complex (MHC) class I, MHC class II, or B cell
Autor:
Heather L. Gray, Wende Lei, Thomas P. Monath, Gwendolyn A. Myers, Thomas H. Ermak, Richard Nichols, Harry Kleanthous, Jennifer Ingrassia, Kathleen Georgakopoulos, Cynthia K. Lee, Ru Ding, Zhen-Zi Zhang, Timothy Tibbitts
Publikováno v:
Infection and Immunity. 66:2879-2886
To determine the optimal inductive sites for immunization against Helicobacter pylori infection, the protective efficacy of recombinant urease (rUre) was assessed for mice given the vaccine by either the oral (p.o.), intranasal (i.n.), or rectal rout
Autor:
Thomas H. Ermak, Gwendolyn A. Myers, Philip Bedford, Jian Liu, Sharone Green, Jeffrey S. Kennedy, Karen McCarthy, Casey Johnson, Francis A. Ennis, Farshad Guirakhoo, Juan Pablo Arroyo, Thomas P. Monath, Niranjan Kanesa-thasan, Alison Deary, Richard Nichols, Sunheang Shin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(17)
West Nile (WN) virus is an important cause of febrile exanthem and encephalitis. Since it invaded the U.S. in 1999, >19,000 human cases have been reported. The threat of continued epidemics has spurred efforts to develop vaccines. ChimeriVax-WN02 is
Autor:
John Catalan, Marion S. Ratterree, Juan Pablo Arroyo, Dennis W. Trent, Chuck Miller, Gwendolyn A. Myers, Thomas P. Monath
The availability of ChimeriVax vaccine technology for delivery of flavivirus protective antigens at the time West Nile (WN) virus was first detected in North America in 1999 contributed to the rapid development of the vaccine candidate against WN vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f234be6ef030de4be687ca902e16f4b
https://europepmc.org/articles/PMC525070/
https://europepmc.org/articles/PMC525070/
Autor:
Richard A. Nichols, Gwendolyn A. Myers, Megan Parsons, F. Rizvi, Fred Mitchell, Samantha Brandler, Dennis W. Trent, Jean Lang, Farshad Guirakhoo, Nancy V. Brown, Konstantin V. Pugachev, Simeon W. Ocran, B. Barrere, A. Travassos, C. Fournier, Thomas P. Monath, Zhenxi Zhang, Inessa S. Levenbook, Ken Draper
Publikováno v:
Journal of virology. 78(9)
To construct chimeric YF/DEN viruses (ChimeriVax-DEN), the premembrane (prM) and envelope (E) genes of yellow fever (YF) 17D virus were replaced with those of each wild-type (WT) dengue (DEN) virus representing serotypes 1 to 4. ChimeriVax-DEN1-4 vac
Autor:
Gwendolyn A. Myers, Heather L. Gray, Thomas P. Monath, Harold Kleanthous, Kathleen Georgakopoulos, Thomas H. Ermak, Jennifer Ingrassia, Timothy Tibbitts, Cynthia K. Lee
Publikováno v:
Vaccine. 17(11-12)
Recombinant Helicobacter pylori urease (rUre) has been shown to confer protection against challenge with Helicobacter felis in mice. The purpose of the present study was to examine duration of the immune response and long-term protective efficacy of