Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Gwenan M. Knight"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The implementation of new antimicrobial resistance stewardship programs is crucial in optimizing antibiotic use. However, prescription choices can be difficult during empiric therapy; clinicians must balance the survival benefits of broader
Externí odkaz:
https://doaj.org/article/fb99f9838e924989a3c31526f550dee0
Publikováno v:
One Health, Vol 19, Iss , Pp 100856- (2024)
Antibiotic use (ABU) in animals is postulated to be a major contributor to selection of antibiotic resistance (ABR) which subsequently causes infections in human populations. However, there are few quantifications of the size of this association. Den
Externí odkaz:
https://doaj.org/article/20b7e54a387347f092c39ab086adc05e
Autor:
Sombo Fwoloshi, Uchizi Chola, Ruth Nakazwe, Timothy Tatila, Tebuho Mateele, Mwewa Kabaso, Theresa Muzyamba, Ilunga Mutwale, Anja St Clair Jones, Jasmin Islam, Enock Chikatula, Aggrey Mweemba, Wilson Mbewe, Lloyd Mulenga, Alexander M. Aiken, J. Anitha Menon, Sarah Lou Bailey, Gwenan M. Knight
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss , Pp 69-77 (2023)
Background: Control of antimicrobial resistance (AMR) relies on local knowledge and local intervention implementation. Effective antibiotic stewardship requires locally-suitable prescribing guidelines. We aimed to use a novel digital tool (the ZARIAp
Externí odkaz:
https://doaj.org/article/7ab7182496fe438594e75f9967ba5ec3
Autor:
Nicolas A. Menzies, Brian W. Allwood, Anna S. Dean, Pete J. Dodd, Rein M. G. J. Houben, Lyndon P. James, Gwenan M. Knight, Jamilah Meghji, Linh N. Nguyen, Andrea Rachow, Samuel G. Schumacher, Fuad Mirzayev, Ted Cohen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract In 2020, almost half a million individuals developed rifampicin-resistant tuberculosis (RR-TB). We estimated the global burden of RR-TB over the lifetime of affected individuals. We synthesized data on incidence, case detection, and treatmen
Externí odkaz:
https://doaj.org/article/67db4f0e99bd484ab56a1ea0cdfb46bf
Publikováno v:
One Health, Vol 17, Iss , Pp 100629- (2023)
Antimicrobial resistance (AMR) is considered a global priority for human health, and reducing antimicrobial use in food animals has been suggested as a key area for interventions aiming to reduce resistant infections in humans. In addition to the eff
Externí odkaz:
https://doaj.org/article/22a9f94a7498449aaeb70cb535a6b884
Autor:
Gwenan M. Knight, Thi Mui Pham, James Stimson, Sebastian Funk, Yalda Jafari, Diane Pople, Stephanie Evans, Mo Yin, Colin S. Brown, Alex Bhattacharya, Russell Hope, Malcolm G. Semple, ISARIC4C Investigators, CMMID COVID-19 Working Group, Jonathan M. Read, Ben S. Cooper, Julie V. Robotham
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background SARS-CoV-2 is known to transmit in hospital settings, but the contribution of infections acquired in hospitals to the epidemic at a national scale is unknown. Methods We used comprehensive national English datasets to determine th
Externí odkaz:
https://doaj.org/article/93390bfb56a2421eb94c4bc8a17a5e7f
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/e54814b33ccf4655b6997e98383ec81a
Autor:
Alicia Rosello, Rosanna C. Barnard, David R. M. Smith, Stephanie Evans, Fiona Grimm, Nicholas G. Davies, Centre for Mathematical Modelling of Infectious Diseases COVID-19 Modelling Working Group, Sarah R. Deeny, Gwenan M. Knight, W. John Edmunds
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background COVID-19 outbreaks still occur in English care homes despite the interventions in place. Methods We developed a stochastic compartmental model to simulate the spread of SARS-CoV-2 within an English care home. We quantified the out
Externí odkaz:
https://doaj.org/article/b3e40a3916e84cb2af7e6ad4855513ca
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) clusters are considered epidemic or nonepidemic based on their ability to spread effectively. Successful transmission could be influenced by dehydration tolerance. Current methods for determ
Externí odkaz:
https://doaj.org/article/5700257b1b73453891ff17d76c0a7984
Autor:
Nichola R. Naylor, Stephanie Evans, Koen B. Pouwels, Rachael Troughton, Theresa Lamagni, Berit Muller-Pebody, Gwenan M. Knight, Rifat Atun, Julie V. Robotham
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
Antimicrobial resistance (AMR) may negatively impact surgery patients through reducing the efficacy of treatment of surgical site infections, also known as the “primary effects” of AMR. Previous estimates of the burden of AMR have largely ignored
Externí odkaz:
https://doaj.org/article/804c1d3ee61a46a3b30305dce0872f34