Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Gwen O. Ivy"'
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 291:R1449-R1456
This study investigated whether changes in GABA-mediated neurotransmission within the nucleus of the solitary tract (NTS) contribute to the changes in breathing (resting ventilation and the acute HVR) that occur following exposure to chronic hypoxia
Publikováno v:
Annals of the New York Academy of Sciences. 1067:375-382
(-)Deprenyl (D) has been shown to be effective in prolonging life span in experimental animals, although, there are some discrepancies in its effect on the life span the even within the same species (rats). The present study aims to clarify the reaso
Autor:
Kenichi Kitani, Maria-Cristina Carrillo, Takako Yamamoto, Gwen O. Ivy, Wakako Maruyama, Setsuko Kanai, Chiyoko Minami
Publikováno v:
Annals of the New York Academy of Sciences. 928:248-260
The free radical theory of aging was initially proposed by Harman1 half a century ago primarily to explain biological aging processes. Although administration of so-called antioxidant chemicals, which have been tested in the past for several decades,
Publikováno v:
Biogerontology. 6:297-302
The effect of (-)deprenyl (D) on prolonging survival has previously been reported in different species of animals. In rats, three studies reported a positive effect, while one study reported a shortening of life spans. In the present study, we attemp
Publikováno v:
Brain Research. 1044:190-196
The amygdala-kindling model is used to study complex partial epilepsy with secondary generalization. The present study was designed to (A) quantify astrocytic changes in the piriform cortex of amygdala-kindled subjects over time and (B) investigate t
Autor:
Maria-Christina Carrillo, Setsuko Kanai, Kayoko Maehara, Kenichi Kitani, Gwen O. Ivy, Ken-ichi Isobe, Chiyoko Minami
Publikováno v:
Mechanisms of Ageing and Development. 123:1087-1100
(--)Deprenyl, a monoamine oxidase B (MAO B) inhibitor is known to upregulate activities of anti-oxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT) in brain dopaminergic regions. The drug is also the sole chemical which has been rep
Publikováno v:
Behavioral Neuroscience. 114:158-172
Publikováno v:
Mechanisms of Ageing and Development. 111:211-221
Limited information is available on the upregulation of endogenous antioxidant enzymes by means of administering various pharmaceuticals and/or chemicals. It has been reported that ursodeoxycholic acid (UDCA), a bile acid originally identified from b
Publikováno v:
Neurochemical Research. 23:1117-1123
Recently we described the pattern of expression of the anti-adhesive glycoprotein SPARC/osteonectin in the developing and adult brain. SPARC mRNA was present in developing blood vessels during neurogenesis, but was not detected in the mature vasculat
Publikováno v:
Brain Research. 730:95-106
In the nervous system, extracellular matrix components are believed to influence cell shape, proliferation and migration during development and following injury. SC1 is a secreted glycoprotein expressed during neural development and in the adult brai