Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gwen O'Driscoll"'
Autor:
Alena Ivanova, Lukas Badertscher, Gwen O'Driscoll, Joakim Bergman, Euan Gordon, Anders Gunnarsson, Camilla Johansson, Michael J. Munson, Cristiana Spinelli, Sara Torstensson, Liisa Vilén, Andrei Voirel, John Wiseman, Janusz Rak, Niek Dekker, Elisa Lázaro‐Ibáñez
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Efficient and targeted delivery of therapeutic agents remains a bottleneck in modern medicine. Here, biochemical engineering approaches to advance the repurposing of extracellular vesicles (EVs) as drug delivery vehicles are explored. Target
Externí odkaz:
https://doaj.org/article/e1d689279e454812aab0d9be5d04dcd4
Autor:
Michael J. Munson, Gwen O’Driscoll, Andreia M. Silva, Elisa Lázaro-Ibáñez, Audrey Gallud, John T. Wilson, Anna Collén, Elin K. Esbjörner, Alan Sabirsh
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Munson et al. develop a high-throughput Galectin-9 reporter based endosomal escape imaging assay to probe correlations between nanoparticle-mediated uptake, endosomal escape frequency, and mRNA translation. By screening various delivery systems, modu
Externí odkaz:
https://doaj.org/article/6d71f1a55da4454e8e456d8390871e01
Autor:
Kai Hu, Paul F. McKay, Karnyart Samnuan, Adrian Najer, Anna K. Blakney, Junyi Che, Gwen O'Driscoll, Martina Cihova, Molly M. Stevens, Robin J. Shattock
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract A vaccine antigen, when launched as DNA or RNA, can be presented in various forms, including intracellular, secreted, membrane‐bound, or on extracellular vesicles (EVs). Whether an antigen in one or more of these forms is superior in immun
Externí odkaz:
https://doaj.org/article/c597076c7d2d40ebbde634f539a11f55
Autor:
Audrey Gallud, Andreia M. Silva, Anna Collén, Alan Sabirsh, Elisa Lázaro-Ibáñez, Gwen O’Driscoll, Michael J. Munson, John T. Wilson, Elin K. Esbjörner
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
RNA-based therapies have great potential to treat many undruggable human diseases. However, their efficacy, in particular for mRNA, remains hampered by poor cellular delivery and limited endosomal escape. Development and optimisation of delivery vect
Autor:
Michael Munson, Gwen O'Driscoll, Andreia Silva, Elisa Lázaro-Ibáñez, Audrey Gallud, John Wilson, Anna Collén, Elin Esbjörner Winters, Alan Sabirsh
RNA-based therapies have great potential to treat many undruggable human diseases. However, their efficacy, in particular for mRNA, remains hampered by poor cellular delivery and limited endosomal escape. Advances in the development and rational opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368b1cbf4e955da31924567f862a9bb7
https://doi.org/10.21203/rs.3.rs-94679/v1
https://doi.org/10.21203/rs.3.rs-94679/v1