Ex Vivo Activation of Red Blood Cell Senescence by Plasma from Sickle-Cell Disease Patients: Correlation between Markers and Adhesion Consequences during Acute Disease Events

Autor: Philippe Chadebech, Gwellaouen Bodivit, Gaétana Di Liberto, Alicia Jouard, Corinne Vasseur, France Pirenne, Pablo Bartolucci

Publikováno v: Biomolecules, Vol 11, Iss 7, p 963 (2021)

BACKGROUND: Blood transfusion remains a key treatment for managing occlusive episodes and painful crises in sickle-cell disease (SCD). In that clinical context, red blood cells (RBCs) from donors and transfused to patients, may be affected by plasma

Externí odkaz: https://doaj.org/article/7ac4c7c78f2845cb92dad9cf63b34104

Complement activation in sickle cell disease: Dependence on cell density, hemolysis and modulation by hydroxyurea therapy

Autor: Lubka T. Roumenina, Philippe Chadebech, Gwellaouen Bodivit, Paula Vieira‐Martins, Anne Grunenwald, Idris Boudhabhay, Victoria Poillerat, Sadaf Pakdaman, Laurent Kiger, Alicia Jouard, Etienne Audureau, France Pirenne, Frédéric Galactéros, Véronique Frémeaux‐Bacchi, Pablo Bartolucci

Publikováno v: American Journal of Hematology
American Journal of Hematology, Wiley, 2020, 95 (5), pp.456-464. ⟨10.1002/ajh.25742⟩
American Journal of Hematology, Wiley, In press, ⟨10.1002/ajh.25742⟩
American Journal of Hematology, 2020, 95 (5), pp.456-464. ⟨10.1002/ajh.25742⟩

International audience; The complement system is an innate immune defense cascade that can cause tissue damage when inappropriately activated. Evidence for complement over activation has been reported in small cohorts of patients with sickle cell dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b527563bbb3f1fcf18df2cfa6c5c8485
https://www.hal.inserm.fr/inserm-03238602/document

Les cytokines plasmatiques chez les patients drépanocytaires comme marqueurs prédictifs de survenue des hémolyses transfusionnelles retardées

Autor: Philippe Chadebech, Gwellaouen Bodivit, Alicia Jouard, Françoise Lelong, Frederic Galacteros, Jean-Claude Lecron, France Pirenne

Publikováno v: Transfusion Clinique et Biologique. 28:S113

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5d73f612a40dd1e6feeddafdd33364a
https://doi.org/10.1016/j.tracli.2021.08.329

Severe hemolysis after plasma transfusion in a neonate with necrotizing enterocolitis,Clostridium perfringensinfection, and red blood cell T-polyagglutination

Autor: Julia Moh-Klaren, Gwellaouen Bodivit, Myriam Jugie, Philippe Chadebech, Laurent Chevret, Mostafa Mokhtari, Xavier Chamillard, Philippe Gallon, Pierre Tissières, Philippe Bierling, Rachid Djoudi, France Pirenne, Nicolas Burin-des-Roziers

Publikováno v: Transfusion. 57:2571-2577

BACKGROUND Red blood cell (RBC) Thomsen-Friedenreich antigen exposure (T activation) in infants with necrotizing enterocolitis (NEC) has occasionally been associated with posttransfusional intravascular hemolysis thought to be due to anti-T antibodie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a844880f5e62a50ea05c49f8a5e8cfda
https://doi.org/10.1111/trf.14196

Cytokine changes in sickle-cell disease patients as markers predictive of the onset of delayed hemolytic transfusion reactions

Autor: Philippe Chadebech, Marie-Amélie de Ménorval, Gwellaouen Bodivit, Alicia Jouard, Sadaf Pakdaman, Francoise Lelong, Anoosha Habibi, Frédéric Galactéros, Jean Claude Lecron, France Pirenne

Publikováno v: Cytokine
Cytokine, Elsevier, 2020, 136, pp.155259. ⟨10.1016/j.cyto.2020.155259⟩

International audience; Background: Changes in cytokine production are known to contribute to the pathogenesis of sickle-cell disease (SCD), particularly in painful acute complications (crises) and episodes of post-transfusion hemolysis. Little is kn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938a28cc9b2b1c2f85bb8eea846918a9
https://doi.org/10.1016/j.cyto.2020.155259