Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Gwangrog Lee"'
Autor:
Hyunji Moon, Chanhyuk Min, Gayoung Kim, Deokhwan Kim, Kwanhyeong Kim, Sang-Ah Lee, Byeongjin Moon, Susumin Yang, Juyeon Lee, Seung-Joo Yang, Steve K. Cho, Gwangrog Lee, Chang Sup Lee, Chul-Seung Park, Daeho Park
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Calcium flux must be carefully controlled during the phagocytosis of apoptotic cells (efferocytosis), although how this occurs is not fully understood. Here, the authors show that the Cereblon E3 ligase regulates Orai1 degradation and subsequently SO
Externí odkaz:
https://doaj.org/article/e974b64c64804ac5944f1149649c6f51
Autor:
Wonseok Hwang, Jungmin Yoo, Yuno Lee, Suyeon Park, Phuong Lien Hoang, HyeokJin Cho, Jeongmin Yu, Thi Minh Hoa Vo, Minsang Shin, Mi Sun Jin, Daeho Park, Changbong Hyeon, Gwangrog Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Metal ions at the active site of an enzyme act as cofactors and their dynamic fluctuations might influence enzyme activity. Here authors use single-molecule FRET to study λ-exonuclease and find that metal-ion-coordination is correlated with enzymati
Externí odkaz:
https://doaj.org/article/2a0749b91eb14221840220e83adac0c3
Autor:
Sang-Ah Lee, Deokhwan Kim, Chanhyuk Min, Byeongjin Moon, Juyeon Lee, Hyunji Moon, Susumin Yang, Chang Sup Lee, Gwangrog Lee, Daeho Park
Publikováno v:
Cells, Vol 10, Iss 11, p 3115 (2021)
Apoptotic cells generated during development and for tissue homeostasis are swiftly and continuously removed by phagocytes via a process called efferocytosis. Efficient efferocytosis can be achieved via transcriptional modulation in phagocytes that h
Externí odkaz:
https://doaj.org/article/d5bb6fd7f3c9485aa7edfde081811276
Autor:
Deokhwan Kim, Hyunji Moon, Hyeokjin Cho, Chanhyuk Min, Byeongjin Moon, Susumin Yang, Juyeon Lee, Sang-Ah Lee, Hyunjin Park, Dae-Hee Lee, Dongtak Jeong, Gwangrog Lee, Daeho Park
Publikováno v:
Cells, Vol 10, Iss 10, p 2702 (2021)
Swift and continuous phagocytosis of apoptotic cells can be achieved by modulation of calcium flux in phagocytes. However, the molecular mechanism by which apoptotic cells modulate calcium flux in phagocytes is incompletely understood. Here, using bi
Externí odkaz:
https://doaj.org/article/1d2a8b4735e74bb8ab8f467c391a04a4
Autor:
Kwanhyeong Kim, Juyeon Lee, Hyunji Moon, Sang-Ah Lee, Deokhwan Kim, Susumin Yang, Dae-Hee Lee, Gwangrog Lee, Daeho Park
Publikováno v:
Cells, Vol 7, Iss 11, p 211 (2018)
Ephexin4 is a guanine nucleotide-exchange factor (GEF) for RhoG and is involved in various RhoG-related cellular processes such as phagocytosis of apoptotic cells and migration of cancer cells. Ephexin4 forms an oligomer via an intermolecular interac
Externí odkaz:
https://doaj.org/article/e283b21cd8a44fc28f13760d11c644cb
Publikováno v:
Biochemical and Biophysical Research Communications. 668:35-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e9da05c7515936ff8d2cb41ef108012
https://doi.org/10.1016/j.bbrc.2023.05.062
https://doi.org/10.1016/j.bbrc.2023.05.062
Publikováno v:
Nucleic Acids Research. 50:2211-2222
Bacterial exonuclease III (ExoIII) is a multifunctional enzyme that uses a single active site to perform two conspicuous activities: (i) apurinic/apyrimidinic (AP)-endonuclease and (ii) 3′→5′ exonuclease activities. The AP endonuclease activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f0eaae18f61da8809513847efd56aa
https://doi.org/10.1093/nar/gkac043
https://doi.org/10.1093/nar/gkac043
Autor:
Raekil Park, Hyunjin Park, Chanhyuk Min, Daeho Park, Byeongjin Moon, Susumin Yang, Sang-Ah Lee, Hyunji Moon, Kwanhyeong Kim, Juyeon Lee, Gwangrog Lee, Deokhwan Kim
Publikováno v:
Molecules and Cells
Phosphatidylserine (PS), a negatively charged phospholipid exclusively located in the inner leaflet of the plasma membrane, is involved in various cellular processes such as blood coagulation, myoblast fusion, mammalian fertilization, and clearance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62372b1a9cb57874a9756e08052d14bc
https://doi.org/10.14348/molcells.2021.2217
https://doi.org/10.14348/molcells.2021.2217
Publikováno v:
RSC Advances. 11:11380-11386
Apurinic/apyrimidinic (AP) endonucleases are vital DNA repair enzymes, and proposed to be a prognostic biomarker for various types of cancer in humans. Numerous DNA sensors have been developed to evaluate the extent of nuclease activity but their DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2855a128efe940742560d32213bdd643
https://doi.org/10.1039/d0ra08051a
https://doi.org/10.1039/d0ra08051a
Autor:
Kwanhyeong Kim, Jihwan Park, Juyeon Lee, Gayoung Kim, Sang-Ah Lee, Chanhyuk Min, Byeongjin Moon, Susumin Yang, Deokhwan Kim, Daeho Park, Hyunji Moon, Jeongjun Park, Hyeokjin Cho, Dae-Hee Lee, Gwangrog Lee
Publikováno v:
Cell Death and Disease, Vol 11, Iss 7, Pp 1-10 (2020)
Cell Death & Disease
Cell Death & Disease
The phosphatidylserine (PS) receptor Tim-4 mediates phagocytosis of apoptotic cells by binding to PS exposed on the surface of these cells, and thus functions as a PS receptor for apoptotic cells. Some of PS receptors are capable of recognizing other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133cf7aa6290ec8cf55081b0fa23c7ea
http://link.springer.com/article/10.1038/s41419-020-02773-7
http://link.springer.com/article/10.1038/s41419-020-02773-7