A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model

Autor: JS McLaren, LJ White, HC Cox, W Ashraf, CV Rahman, GW Blunn, AE Goodship, RA Quirk, KM Shakesheff, R Bayston, BE Scammell

Publikováno v: European Cells & Materials, Vol 27, Pp 332-349 (2014)

Open fractures are at risk of serious infection and, if infected, require several surgical interventions and courses of systemic antibiotics. We investigated a new injectable formulation that simultaneously hardens in vivo to form a porous scaffold f

Externí odkaz: https://doaj.org/article/6dd328d445004db9b2ec84c9acca2c03

Composite Ceramic Bone Graft Substitute in the Treatment of Locally Aggressive Benign Bone Tumours

Autor: OS Schindler, SR Cannon, TWR Briggs, GW Blunn

Publikováno v: Journal of Orthopaedic Surgery, Vol 16 (2008)

Purpose. To report the use of a composite ceramic bone graft substitute containing calcium sulphate and hydroxyapatite (HA) in the treatment of large expansive osteolytic benign bone tumours. Methods. 4 women and 9 men aged 8 to 49 (mean, 22) years w

Externí odkaz: https://doaj.org/article/9ca01229452540988c5b73c175fd1e8d

A scoring system to evaluate stability of percutaneous osseointegrated implants for transfemoral amputation with validation in the ITAP clinical trial.

Autor: Ahmed K; Center for Bionics and Pain Research, Mölndal, Sweden.; Division of Surgery and Interventional Science, University College London, Stanmore, UK., Blunn GW; Division of Surgery and Interventional Science, University College London, Stanmore, UK.; School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.

Publikováno v: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine [Proc Inst Mech Eng H] 2024 Apr; Vol. 238 (4), pp. 412-422. Date of Electronic Publication: 2024 Feb 28.

Open-porous magnesium-based scaffolds withstand in vitro corrosion under cyclic loading: A mechanistic study.

Autor: Bonithon R; Zeiss Global Centre, School of Mechanical and Design Engineering, University of Portsmouth, Anglesea Road, PO1 3DJ, Portsmouth, United Kingdom., Lupton C; Zeiss Global Centre, School of Mechanical and Design Engineering, University of Portsmouth, Anglesea Road, PO1 3DJ, Portsmouth, United Kingdom., Roldo M; School of Pharmacy and Biomedical Sciences, University of Portsmouth, White Swan Road, PO1 2DT, Portsmouth, United Kingdom., Dunlop JN; School of the Environment, Geography & Geosciences, University of Portsmouth, Burnaby Road, PO1 3QL, Portsmouth, United Kingdom., Blunn GW; School of Pharmacy and Biomedical Sciences, University of Portsmouth, White Swan Road, PO1 2DT, Portsmouth, United Kingdom., Witte F; Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Charité - Universitätsmedizin Berlin, Aßmannshauser Straße 4-6, 14197, Berlin, Germany.; Biotrics Bioimplants AG, Ullsteinstr. 108, 12109, Berlin, Germany., Tozzi G; Zeiss Global Centre, School of Mechanical and Design Engineering, University of Portsmouth, Anglesea Road, PO1 3DJ, Portsmouth, United Kingdom.

Publikováno v: Bioactive materials [Bioact Mater] 2022 Apr 29; Vol. 19, pp. 406-417. Date of Electronic Publication: 2022 Apr 29 (Print Publication: 2023).

Mesenchymal stromal cells and platelet-rich plasma promote tendon allograft healing in ovine anterior cruciate ligament reconstruction.

Autor: Hexter AT; Division of Surgery and Interventional Science, University College London (UCL), London, UK. a.hexter@ucl.ac.uk.; Institute of Orthopaedics and Musculoskeletal Sciences, Division of Surgery and Interventional Science, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, London, HA7 4LP, UK. a.hexter@ucl.ac.uk., Sanghani-Kerai A; Division of Surgery and Interventional Science, University College London (UCL), London, UK., Heidari N; Royal London Hospital and Orthopaedic Specialists (OS), London, UK., Kalaskar DM; Division of Surgery and Interventional Science, University College London (UCL), London, UK., Boyd A; Division of Surgery and Interventional Science, University College London (UCL), London, UK., Pendegrass C; Division of Surgery and Interventional Science, University College London (UCL), London, UK., Rodeo SA; Hospital of Special Surgery (HSS), New York, USA., Haddad FS; University College London Hospitals, London, UK., Blunn GW; University of Portsmouth, Portsmouth, UK.

Publikováno v: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA [Knee Surg Sports Traumatol Arthrosc] 2021 Nov; Vol. 29 (11), pp. 3678-3688. Date of Electronic Publication: 2020 Dec 17.