Intrarectal Dehydroleucodine Suppresses Trinitrobenzene Sulfonic Acid–Induced Colitis in Rats, A Model for Inflammatory Bowel Disease

Autor: Oscar S. Giordano, A. O. M. María, Graciela Haydée Wendel, Lilian Eugenia Pelzer, Guzmán Ja, Nora S. Domínguez, Luis Scardapane, Fabian Mohamed

Publikováno v: Pharmaceutical Biology. 45:316-323

Dehydroleucodine (DhL), isolated from Artemisia douglasiana. Besser (Asteraceae), prevents damage in acetic acid–induced colitis in rats. The trinitrobenzene sulfonic acid (TNBS)-induced model of chronic inflammation of the rat colon was used to de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77a41f908ef39747fdd13227f4be6eeb
https://doi.org/10.1080/13880200701212866

Colloid in the pituitary pars distalis of viscacha (Lagostomus maximus maximus): Ultrastructure and occurrence in relation to season, sex, and growth

Autor: Luis Scardapane, Ramón S. Piezzi, Guzmán Ja, Teresa Fogal, Fabian Mohamed, Susana Dominguez

Publikováno v: The Anatomical Record. 258:252-261

Randomly distributed extracellular colloidal accumulations were observed in the pars distalis of viscacha (Lagostomus maximus maximus). They were preferentially located in the peripheral zone of the gland and showed variability in shape and size. Two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01813de180d31aee4ecca41d51ce3403
https://doi.org/10.1002/(sici)1097-0185(20000301)258:3<252::aid-ar4>3.0.co

Probable effect of photoperiod on seasonal variation in the nuclear volume of the adrenal cortex of viscacha (Lagostomus maximus maximus)

Autor: M. Delgado, Guzmán Ja, A.C. Ribes, Fabian Mohamed, Ramón S. Piezzi, Luis Scardapane, Servando Álvarez Domínguez

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 32, Iss 9, Pp 1115-1120 (1999)
Brazilian Journal of Medical and Biological Research, Volume: 32, Issue: 9, Pages: 1115-1120, Published: SEP 1999
Brazilian Journal of Medical and Biological Research v.32 n.9 1999
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC

The neuroendocrine system regulates several organic functions such as reproduction, metabolism and adaptation to the environment. This system shows seasonal changes linked to the environment. The experimental model used in the present study was Lagos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c24692aef0606e85157de5926310fbc
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000900010

GASTRIC CYTOPROTECTIVE ACTIVITY OF DEHYDROLEUCODINE IN RATS. ROLE OF NITRIC OXIDE

Autor: Graciela Haydée Wendel, A. O. M. María, Eduardo Guerreiro, Oscar S. Giordano, Guzmán Ja

Publikováno v: Pharmacological Research. 37:281-284

Previously we reported that dehydroleucodine (DhL), a sesquiterpene lactone, shows gastric and duodenal cytoprotective activity. The mechanism is not mediated by antiacid secretory action; DhL stimulated mucus production and indomethacin pretreatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ff71f6471ccb1ffd7e101fbaf9ed5e
https://doi.org/10.1006/phrs.1998.0291

Gastric Cytoprotective Activity of Dehydroleucodine in Rats. Role of Prostaglandins

Autor: A. O. M. María, Guzmán Ja, Eduardo Guerreiro, Oscar S. Giordano, Graciela Haydée Wendel, Ana M. Franchi, Martha Gimeno

Publikováno v: Biological and Pharmaceutical Bulletin. 21:335-338

Previously, we reported that dehydroleucodine (DhL), a sesquiterpene lactone, protected the gastric mucosa of rats from absolute ethanol-induced lesions in a dose-dependent fashion. The mechanism is not mediated by an antiacid secretory action and Dh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cf728f72b586c8802161b5ed2830cc
https://doi.org/10.1248/bpb.21.335