Microglia-mediated degradation of perineuronal nets promotes pain.

Autor: Tansley S; Department of Anesthesia, McGill University, Montreal, QC, Canada.; Department of Psychology, Faculty of Science, McGill University, Montreal, QC, Canada., Gu N; Department of Anesthesia, McGill University, Montreal, QC, Canada., Guzmán AU; Department of Anesthesia, McGill University, Montreal, QC, Canada., Cai W; Department of Anesthesia, McGill University, Montreal, QC, Canada., Wong C; Department of Anesthesia, McGill University, Montreal, QC, Canada., Lister KC; Department of Anesthesia, McGill University, Montreal, QC, Canada., Muñoz-Pino E; Department of Psychiatry and Neuroscience, CERVO Brain Research Centre, Université Laval, Québec, QC, Canada., Yousefpour N; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada., Roome RB; Institut de Recherches Cliniques de Montreal (IRCM), Montreal, QC, Canada., Heal J; Department of Anesthesia, McGill University, Montreal, QC, Canada., Wu N; Department of Anesthesia, McGill University, Montreal, QC, Canada., Castonguay A; Department of Psychiatry and Neuroscience, CERVO Brain Research Centre, Université Laval, Québec, QC, Canada., Lean G; Department of Physiology, McGill University, Montreal, QC, Canada., Muir EM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Kania A; Institut de Recherches Cliniques de Montreal (IRCM), Montreal, QC, Canada.; Department of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada., Prager-Khoutorsky M; Department of Physiology, McGill University, Montreal, QC, Canada., Zhang J; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.; Faculty of Dental Medicine and Oral Health Sciences, Montreal, QC, Canada.; Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada., Gkogkas CG; Biomedical Research Institute, Foundation for Research and Technology-Hellas, University Campus, 45110 Ioannina, Greece., Fawcett JW; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Centre for Reconstructive Neuroscience, Institute for Experimental Medicine CAS, Prague, Czech Republic., Diatchenko L; Department of Anesthesia, McGill University, Montreal, QC, Canada.; Faculty of Dental Medicine and Oral Health Sciences, Montreal, QC, Canada.; Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada., Ribeiro-da-Silva A; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.; Department of Anatomy and Cell Biology, McGill University, Montreal, QC, Canada.; Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada., De Koninck Y; Department of Psychiatry and Neuroscience, CERVO Brain Research Centre, Université Laval, Québec, QC, Canada.; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.; Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada., Mogil JS; Department of Anesthesia, McGill University, Montreal, QC, Canada.; Department of Psychology, Faculty of Science, McGill University, Montreal, QC, Canada.; Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada., Khoutorsky A; Department of Anesthesia, McGill University, Montreal, QC, Canada.; Faculty of Dental Medicine and Oral Health Sciences, Montreal, QC, Canada.; Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada.

Publikováno v: Science (New York, N.Y.) [Science] 2022 Jul; Vol. 377 (6601), pp. 80-86. Date of Electronic Publication: 2022 May 26.