Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Guzel F. Zakyrjanova"'
Publikováno v:
Free Radical Biology and Medicine. 174:121-134
Inflammatory reactions induce changes in the neuromuscular system. The mechanisms underlying this link are unclear. Besides cytokines and reactive oxygen species (ROS), production of an antiviral oxysterol 25-hydroxycholesterol (25HC) by immune cells
Publikováno v:
Free radical biologymedicine. 155
Cd2+ is one of the most widespread environmental pollutants and its accumulation in central and peripheral nervous systems leads to neurotoxicity as well as aggravation of common neurodegenerative diseases. Mechanism of the Cd2+ toxicity is far from
Autor:
Svetlana V. Fedorenko, Asiya R. Mustafina, Irek R. Nizameev, Alsu R. Mukhametshina, Konstantin A. Petrov, Guzel F. Zakyrjanova, L. F. Nurullin, Oleg G. Sinyashin, Alexey M. Petrov
Publikováno v:
ACS Applied Materials & Interfaces. 10:14948-14955
The present work for the first time introduces nanosensors for luminescent monitoring of acetylcholinesterase (AChE)-catalyzed hydrolysis of endogenous acetylcholine (ACh) released in neuromuscular junctions of isolated muscles. The sensing function
Autor:
Guzel F. Zakyrjanova, Kamilla A. Mukhutdinova, A. R. Giniatullin, Alexey M. Petrov, Eva A. Kuznetsova
Publikováno v:
Life Sciences. 273:119300
Aims Plasma hyperlipidemia is a protective factor in amyotrophic lateral sclerosis (ALS) while cholesterol-lowering drugs aggravate the pathology. We hypothesize that this phenomenon can be linked with membrane lipid alterations in the neuromuscular
Autor:
Guzel F. Zakyrjanova, Kamilla A. Mukhutdinova, Alexey M. Petrov, M. R. Kasimov, Milausha R. Gumerova
Publikováno v:
Neuropharmacology. 150
Elimination of brain cholesterol occurs in the form of 24S-hydroxycholesterol (24S-HCh) that may modulate physiological processes outside the brain. Here, using microelectrode recording of postsynaptic responses (end-plate potentials, EPPs) and fluor
Autor:
M. R. Kasimov, Kamilla A. Mukhutdinova, Alexey M. Petrov, A. R. Giniatullin, Guzel F. Zakyrjanova
Publikováno v:
Molecular and cellular neurosciences. 88
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the initial denervation of skeletal muscle and subsequent death of motor neurons. A dying-back pattern of ALS suggests a crucial role for neuromuscular junction dysf
Publikováno v:
Biochimica et biophysica acta. 1861(7)
Cholesterol oxidation products frequently have a high biological activity. In the present study, we have used microelectrode recording of end plate currents and FM-based optical detection of synaptic vesicle exo-endocytosis to investigate the effects