Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Guyu Ho"'
Autor:
Yunting Zhou, Qi Hu, Fuyi Chen, Juan Zhang, Jincheng Guo, Hongwu Wang, Jiang Gu, Lian Ma, Guyu Ho
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 12, Pp 1625-1633 (2015)
Human umbilical cord matrix-derived stem cells (uMSCs), owing to their cellular and procurement advantages compared with mesenchymal stem cells derived from other tissue sources, are in clinical trials to treat type 1 (T1D) and type 2 diabetes (T2D).
Externí odkaz:
https://doaj.org/article/da21c4e422814b77a942a8239910b809
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 6, Pp 723-730 (2014)
Major depression disorder (MDD) or depression is highly prevalent in individuals with diabetes, and the depressive symptoms are more severe and less responsive to antidepressant therapies in these patients. The underlying mechanism is little understo
Externí odkaz:
https://doaj.org/article/5458fc14862241829c0064e6c5432b3a
Publikováno v:
PLoS ONE, Vol 8, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/a0e3429e073c47e4bbb4757c9a0c895b
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82502 (2013)
In this study, we attempted to design a model using Sprague-Dawley rats to better reproduce perinatal systemic hypoxic-ischemic encephalopathy (HIE) in early preterm newborns. On day 21 of gestation, the uterus of pregnant rats were exposed and the b
Externí odkaz:
https://doaj.org/article/889412bd86dc407f9f73f1b9867dbfe9
Autor:
Qiuling Tang, Qiurong Chen, Xiulan Lai, Sizheng Liu, Yezeng Chen, Zexin Zheng, Qingdong Xie, Martin Maldonado, Zhiwei Cai, Shan Qin, Guyu Ho, Lian Ma
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81844 (2013)
Human umbilical cord mesenchymal stem cells (HUMSCs) are highly proliferative and can be induced to differentiate into advanced derivatives of all three germ layers. Thus, HUMSCs are considered to be a promising source for cell-targeted therapies and
Externí odkaz:
https://doaj.org/article/4e35b01280af4986b7f34c74aa3d9d30
Autor:
Fuyi Chen, Juan Zhang, Hongwu Wang, Lian Ma, Yunting Zhou, Jincheng Guo, Jiang Gu, Guyu Ho, Qi Hu
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 12, Pp 1625-1633 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms
Human umbilical cord matrix-derived stem cells (uMSCs), owing to their cellular and procurement advantages compared with mesenchymal stem cells derived from other tissue sources, are in clinical trials to treat type 1 (T1D) and type 2 diabetes (T2D).
Publikováno v:
Journal of Molecular Endocrinology. 54:125-135
Hypothalamic glucose-sensing neurons regulate the expression of genes encoding feeding-related neuropetides POMC, AgRP, and NPY – the key components governing metabolic homeostasis. AMP-activated protein kinase (AMPK) is postulated to be the molecu
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 7, Iss 6, Pp 723-730 (2014)
Disease Models & Mechanisms, Vol 7, Iss 6, Pp 723-730 (2014)
Major depression disorder (MDD) or depression is highly prevalent in individuals with diabetes, and the depressive symptoms are more severe and less responsive to antidepressant therapies in these patients. The underlying mechanism is little understo
Autor:
Guyu Ho, Philip A. Carpino
Publikováno v:
Expert Opinion on Therapeutic Patents. 18:1253-1263
Background: Ghrelin is a stomach-derived octanoylated hormone that has been implicated in body weight regulation and glucose homeostasis. It mediates its pharmacological activities primarily through the ghrelin receptor (GhR). The discovery of small
Publikováno v:
Pharmacology. 79:114-121
In this study, we investigated the activation of the serum response element (SRE) by the D2 dopamine receptor (D2R) agonist quinpirole. Stimulation of CHO cells expressing the D2R by quinpirol evoked a dose-dependent SRE activation, which was complet