Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Guy de Martynoff"'
Autor:
Zuzana Antosova, Nada Podzimkova, Jakub Tomala, Katerina Augustynkova, Katerina Sajnerova, Eva Nedvedova, Milada Sirova, Guy de Martynoff, David Bechard, Ulrich Moebius, Marek Kovar, Radek Spisek, Irena Adkins
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
SOT101 is a superagonist fusion protein of interleukin (IL)-15 and the IL-15 receptor α (IL-15Rα) sushi+ domain, representing a promising clinical candidate for the treatment of cancer. SOT101 among other immune cells specifically stimulates natura
Externí odkaz:
https://doaj.org/article/f6cbe7a311f44d1492d58b49afd67953
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/4f58b86012594ed1972b378a51a307b4
Autor:
Irena Adkins, Zuzana Antosova, Klara Danova, Kamila Hladikova, Katerina Augustynkova, Katerina Sajnerova, Nada Podzimkova, Pavel Marasek, Guy de Martynoff, David Bechard, Ulrich Moebius, Radek Spisek
Publikováno v:
Cancer Research. 82:3510-3510
SOT201 is a novel immunocytokine consisting of a monoclonal humanized, Fc silenced antibody against PD-1 fused to a covalent RLI-15 complex of a human IL-15 mutein linked to the high-affinity binding site of the IL-15Rα, the sushi+ domain. SOT201 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fbcf09aa17b7b4698420a47183394c
https://doi.org/10.1158/1538-7445.am2022-3510
https://doi.org/10.1158/1538-7445.am2022-3510
Autor:
David Bechard, Radek Spisek, Ulrich Moebius, Guy de Martynoff, Zuzana Antosova, Irena Adkins, Eva Nedvedova, Nada Podzimkova, Marketa Jiratova
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background SO-C101 is a superagonist fusion protein of interleukin (IL)-15 and the IL-15 receptor α (IL-15Rα) sushi+ domain, representing a promising clinical candidate for the treatment of cancer. SO-C101 specifically stimulates natural killer (NK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3425525d7b0efe94226a1ec0b18060d
https://doaj.org/article/1f96a615e4d749549ee66603eabc709c
https://doaj.org/article/1f96a615e4d749549ee66603eabc709c
Autor:
Guy de Martynoff, Nada Hradilova, David Bechard, Romana Mikyšková, Ulrich Moebius, Milan Reiniš, Radek Spisek, Irena Adkins
Publikováno v:
Cancer Research. 80:6686-6686
SO-C101 (RLI-15) is a superagonist fusion protein of interleukin (IL)-15 and the IL-15 receptor α (IL-15Rα) sushi+ domain designed to bypass the need of endogenous IL-15Rα, thereby leveraging the activity of IL-15 in vivo on target immune cells an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7dd49acfe3e1579be72d34c9c098e7c
https://doi.org/10.1158/1538-7445.am2020-6686
https://doi.org/10.1158/1538-7445.am2020-6686
Autor:
Guy de Martynoff, Ulrich Moebius, Romana Mikyšková, David Bechard, Marek Kovar, Nada Hradilova, Milan Reiniš, Irena Adkins, Jakub Tomala, Lenka Sadilkova, Barbora Tomalova, Radek Spisek
Publikováno v:
Cancer Research. 78:3775-3775
RLI-15, a superagonist fusion protein of interleukin (IL)-15 and the IL-15 receptor α (IL-15Rα) sushi+ domain represents a promising candidate for the induction of anti-tumor immunity. RLI-15 was designed to bypass the need of endogenous IL-15Rα,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a848a9c0a72078e1eefa5c494a9699b
https://doi.org/10.1158/1538-7445.am2018-3775
https://doi.org/10.1158/1538-7445.am2018-3775
Autor:
Ann Venneman, R. A. Heijtink, Paul Vandeponseele, Guy De Martynoff, Fons Bosman, Geert Maertens, Lieven Stuyver, Annemie Ducatteeuw, Ann Wyseur
Publikováno v:
Viral Hepatitis and Liver Disease ISBN: 9784431682578
In order to measure the prevalence or the degree of cross-reactivity of hepatitis C virus (HCV) anti-E1 antibodies in a panel of 100 HCV sera that were previously classified into 4 genotypes and their subtypes by means of a new Line Probe Assay (LiPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea6870d890ff97b42b062ec7922fd1fd
https://doi.org/10.1007/978-4-431-68255-4_77
https://doi.org/10.1007/978-4-431-68255-4_77
Publikováno v:
European Journal of Biochemistry. 147:59-64
The sequence of the first 2831 nucleotides of bovine thyroglobulin mRNA has been determined from the analysis of a cDNA clone. Following a 41-nucleotide 5' untranslated sequence, a single open-reading frame encoding 930 amino acids was observed. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d449fcb8a68fddf7f67512dc949c173
https://doi.org/10.1111/j.1432-1033.1985.tb08718.x
https://doi.org/10.1111/j.1432-1033.1985.tb08718.x
Publikováno v:
European Journal of Biochemistry. 164:591-599
The structural organization of the bovine thyroglobulin gene has been investigated by a combination of Southern genomic blotting and direct analysis of cloned gene fragments isolated from a chromosomal DNA library. The entire locus is spread over mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c4cd97bb15274693d7e3f085830241
https://doi.org/10.1111/j.1432-1033.1987.tb11168.x
https://doi.org/10.1111/j.1432-1033.1987.tb11168.x
Autor:
Etienne Pays, Huguette Brocas, Frank Gannon, Daniel Christophe, Guy De Martynoff, Gilbert Vassart
Publikováno v:
European Journal of Biochemistry. 111:419-423
Double-stranded thyroglobulin complementary DNA (cDNA) was synthesized from purified 33-S bovine thyroglobulin mRNA. This synthetic structural gene has previously been shown to contain three sites for the restriction endonuclease HindIII, yielding tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0e1f9670d808b25a323046baca64bf
https://doi.org/10.1111/j.1432-1033.1980.tb04956.x
https://doi.org/10.1111/j.1432-1033.1980.tb04956.x