Zobrazeno 1 - 10 of 65 pro vyhledávání: '"Guy Zuber"'
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Akademický článek
Performance of Pyridylthiourea‐Polyethylenimine Polyplex for siRNA‐Mediated Liver Cancer Therapy in Cell Monolayer, Spheroid, and Tumor Xenograft Models
Autor: Jean Baptiste Gossart, Etienne Pascal, Florent Meyer, Emilie Heuillard, Mathieu Gonçalves, Francine Gossé, Eric Robinet, Benoît Frisch, Cendrine Seguin, Guy Zuber
Publikováno v: Global Challenges, Vol 1, Iss 4, Pp n/a-n/a (2017)
Medical application of siRNAs relies on methods for delivering nucleic acids into the cytosol. Synthetic carriers, which assemble with nucleic acids into delivery systems, show promises for cancer therapy but efficiency remains to be improved. In her
Externí odkaz: https://doaj.org/article/0c8fe974fe604868974348546fcd08f3
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5
Gold labelling of a green fluorescent protein (GFP)-tag inside cells using recombinant nanobodies conjugated to 2.4 nm thiolate-coated gold nanoparticles
Autor: Dris Ihiawakrim, Nadja Groysbeck, Anne Marie Haeberlé, Mariel Donzeau, Mounib Bahri, Ovidiu Ersen, Audrey Stoessel, Patrick Schultz, Guy Zuber, Stéphane Ory, Danièle Spehner
Publikováno v: Nanoscale Advances
Nanoscale Advances, RSC, In press, ⟨10.1039/D1NA00256B⟩
Nanoscale Advances, 2021, 3 (24), pp.6940-6948. ⟨10.1039/D1NA00256B⟩
The advances in the microscopy technology have prompted efforts to improve the reagents required to recognize specific molecules within the intracellular environment. For high-resolution electron microscopy, conjugation of selective binders originati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f36eb531fac56b15a0854772fbb12c
https://doi.org/10.1039/d1na00256b
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6
Self-Associating Peptides for Modular Bifunctional Conjugation of Tetramer Macromolecules in Living Cells
Autor: Agnès M. Cordonnier, Mariel Donzeau, Yves Nominé, Annick Dejaegere, Bruno Chatton, Frank Dietsch, Marc Vigneron, Guy Zuber, Laurent Bianchetti
Publikováno v: Bioconjugate Chemistry
Bioconjugate Chemistry, 2019, 30 (6), pp.1734-1744. ⟨10.1021/acs.bioconjchem.9b00276⟩
Monitoring the assembly of macromolecules to design entities with novel properties can be achieved either chemically creating covalent bonds or by noncovalent connections using appropriate structural motifs. In this report, two self-associating pepti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16da2632911f6dbb7df3bbe01a03c70b
https://doi.org/10.1021/acs.bioconjchem.9b00276
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7
Inhibiting FAK–Paxillin Interaction Reduces Migration and Invadopodia-Mediated Matrix Degradation in Metastatic Melanoma Cells
Autor: Mousson A, Legrand M, Steffan T, Vauchelles R, Carl P, Gies J, Lehmann M, Guy Zuber, De Mey J, Dujardin D, Sick E, Rondé P
Publikováno v: Cancers
Cancers, MDPI, 2021, 13 (8), pp.1871. ⟨10.3390/cancers13081871⟩
Cancers, Vol 13, Iss 1871, p 1871 (2021)
Europe PubMed Central
Volume 13
Issue 8
Simple Summary The focal adhesion kinase (FAK) is over-expressed in a variety of human tumors and is involved in many aspects of the metastatic process. This has led to the development of small inhibitors of FAK kinase function which are currently ev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::852649be8c9e87d5946c5d01d31fb0ed
https://www.mdpi.com/2072-6694/13/8/1871
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8
Modular Conjugation of a Potent Anti-HER2 Immunotoxin Using Coassociating Peptides
Autor: Mariel Donzeau, Celia Deville, Yves Nominé, Nikita Pallaoro, Lina Barret, Bruno Chatton, Marie Blocat, Ambre Bender, Audrey Stoessel, Lucile Guyot, Leonel Nguekeu-Zebaze, Guy Zuber, Nadja Groysbeck, Laetitia Voilquin, Murielle Masson, Thomas Lutz
Publikováno v: Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2020, 31 (10), pp.2421-2430. ⟨10.1021/acs.bioconjchem.0c00482⟩
Immunotoxins are emerging candidates for cancer therapeutics. These biomolecules consist of a cell-targeting protein combined to a polypeptide toxin. Associations of both entities can be achieved either chemically by covalent bonds or genetically cre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f2c9a574f7317a827404a0d150ea01
https://hal.archives-ouvertes.fr/hal-03005245
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9
Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides
Autor: Nassera Tounsi, Antoine Kichler, Guy Zuber, Manuela Chiper, Ryszard Kole
Publikováno v: Journal of Controlled Release
Journal of Controlled Release, Elsevier, 2017, 246, pp.60-70. ⟨10.1016/j.jconrel.2016.12.005⟩
Efficiency of polyethylenimine (PEI) for nucleic acid delivery is affected by the size of the carrier and length of the nucleic acids. For instance, PEIs with molecular weights between 10-30kDa provide optimal DNA delivery activity whereas PEIs with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90681356950c7da71e4940a1f0b74041
https://doi.org/10.1016/j.jconrel.2016.12.005
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10
MACROMOLECULAR CONJUGATES FOR NON-VIRAL NUCLEIC ACID DELIVERY
Autor: Guy Zuber, Mark D. Ericson, Kevin G. Rice
Publikováno v: Advanced Textbook on Gene Transfer, Gene Therapy and Genetic Pharmacology: Principles, Delivery and Pharmacological and Biomedical Applications of Nucleotide-Based Therapies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c7b60d155e51e1d4430449b107ed0da
https://doi.org/10.1142/9781786346889_0014
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