Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Guy Winderickx"'
Autor:
Peter Persich, Steven Hostyn, Céline Joie, Jeroen A. Pikkemaat, Edwin P. Romijn, Bert U. W. Maes, Guy Winderickx
Publikováno v:
Journal of pharmaceutical sciences
Forced degradation studies are an important tool for a systematic assessment of decomposition pathways and identification of reactive sites in active pharmaceutical ingredients (APIs). Two methodologies have been combined in order to provide a deeper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881eb9070df379083ce7b922b0545d77
https://pubmed.ncbi.nlm.nih.gov/28108379
https://pubmed.ncbi.nlm.nih.gov/28108379
Autor:
Rit Mermans, and Ildiko M. Buck, I. M. Mcdonald, Guy Winderickx, Bert Willemsens, Jaak Langens, Dominic Ormerod, S. Barret Kalindjian
Publikováno v:
Organic Process Research & Development. 9:499-507
A practical and scalable synthesis was developed that was used to prepare multikilogram batches of gastrazole, a selective cholecystokinin-2 receptor antagonist. In addition, evidence was found to indicate an amide bond-forming reaction proceeded via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a248312b2f2e4c7eb563d4376666f645
https://doi.org/10.1021/op0500638
https://doi.org/10.1021/op0500638
Autor:
Steven Hostyn, Bart Van Hoof, Tom Huybrechts, Maurice Hermans, Sara Vrielynck, Guy Winderickx, Wim Vermeulen, Carla De Neef
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 70
The photochemical stability of (1'R,2'S,3'S,4'R)-4'-azido-2'-deoxy-2'-methylcytidine hydrochloride, a new anti-HCV agent, was investigated. Aqueous solutions and bulk drug powder of the drug candidate were exposed to UV-visible light, complying with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f6190ddbce427b04860ab353ab6f98
https://pubmed.ncbi.nlm.nih.gov/22841557
https://pubmed.ncbi.nlm.nih.gov/22841557