Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Guy T. Clifton"'
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 11, Iss , Pp 100251- (2023)
Pancreatic cancer remains an inauspicious malignancy with poor long-term outcomes. The majority of patients present with advanced disease; many suffer from consequences of local progression of disease, and survival rates remain unacceptably poor. Cen
Externí odkaz:
https://doaj.org/article/f426b2dcf532485485c97e9ae921a2cf
Autor:
Patrick M. McCarthy, Franklin A. Valdera, Todd R. Smolinsky, Alexandra M. Adams, Anne E. O’Shea, Katryna K. Thomas, Spencer Van Decar, Elizabeth L. Carpenter, Ankur Tiwari, John W. Myers, Diane F. Hale, Timothy J. Vreeland, George E. Peoples, Alex Stojadinovic, Guy T. Clifton
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Checkpoint inhibitors have invigorated cancer immunotherapy research, including cancer vaccination. Classic early phase trial design and endpoints used in developing chemotherapy are not suited for evaluating all forms of cancer treatment. Peripheral
Externí odkaz:
https://doaj.org/article/bc7c7eccb0dc43ea82221b1220d847ed
Autor:
Robert C. Chick, Mark B. Faries, Diane F. Hale, Phillip M Kemp Bohan, Annelies T. Hickerson, Timothy J. Vreeland, John W. Myers III, Jessica L. Cindass, Tommy A. Brown II, John Hyngstrom, Adam C. Berger, James W. Jakub, Jeffrey J. Sussman, Montaser Shaheen, Guy T. Clifton, Hyohyun Park, Amanda J. Sloan, Thomas Wagner, George E. Peoples
Publikováno v:
Cancer Medicine, Vol 10, Iss 13, Pp 4302-4311 (2021)
Abstract Background Checkpoint inhibitors (CPI) in combination with cell‐based vaccines may produce synergistic antitumor immunity. The primary analysis of the randomized and blinded phase IIb trial in resected stage III/IV melanoma demonstrated TL
Externí odkaz:
https://doaj.org/article/a6753864134f45a6a3f365c4aa4d21de
Autor:
Tommy A. Brown, Kevin Byrd, Timothy J. Vreeland, Guy T. Clifton, Doreen O. Jackson, Diane F. Hale, Garth S. Herbert, John W. Myers, Julia M. Greene, John S. Berry, Jonathan Martin, John C. Elkas, Thomas P. Conrads, Kathleen M. Darcy, Chad A. Hamilton, George L. Maxwel, George E. Peoples
Publikováno v:
Cancer Medicine, Vol 8, Iss 10, Pp 4678-4687 (2019)
Abstract Background E39, an HLA‐A2‐restricted, immunogenic peptide derived from the folate‐binding protein (FBP), is overexpressed in multiple malignancies. We conducted a phase I/IIa trial of the E39 + GM‐CSF vaccine with booster inoculation
Externí odkaz:
https://doaj.org/article/f15fd5bad15e44cabf5f4b8e235a3c91
Autor:
Anne E. O'Shea, Guy T. Clifton, Na Qiao, Brandy M. Heckman-Stoddard, Malgorzata Wojtowicz, Eileen Dimond, Isabelle Bedrosian, Diane Weber, Judy E. Garber, Alexander Husband, Ricardo Pastorello, J. Jack Lee, Mike Hernandez, Diane D. Liu, Lana A. Vornik, Powel H. Brown, Gheath Alatrash, George E. Peoples, Elizabeth A. Mittendorf
Publikováno v:
Cancer Prevention Research. :OF1-OF9
NeuVax is a vaccine comprised of the HER2-derived MHC class I peptide E75 (nelipepimut-S, NPS) combined with GM-CSF. We completed a randomized trial of preoperative vaccination with NeuVax versus GM-CSF alone in patients with ductal carcinoma in situ
Autor:
Elizabeth A. Mittendorf, George E. Peoples, Gheath Alatrash, Powel H. Brown, Lana A. Vornik, Diane D. Liu, Mike Hernandez, J. Jack Lee, Ricardo Pastorello, Alexander Husband, Judy E. Garber, Diane Weber, Isabelle Bedrosian, Eileen Dimond, Malgorzata Wojtowicz, Brandy M. Heckman-Stoddard, Na Qiao, Guy T. Clifton, Anne E. O'Shea
NeuVax is a vaccine comprised of the HER2-derived MHC class I peptide E75 (nelipepimut-S, NPS) combined with GM-CSF. We completed a randomized trial of preoperative vaccination with NeuVax versus GM-CSF alone in patients with ductal carcinoma in situ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f651670fa931553a9dd3bc374ba8183
https://doi.org/10.1158/1940-6207.c.6642622.v1
https://doi.org/10.1158/1940-6207.c.6642622.v1
Autor:
Elizabeth A. Mittendorf, George E. Peoples, Gheath Alatrash, Powel H. Brown, Lana A. Vornik, Diane D. Liu, Mike Hernandez, J. Jack Lee, Ricardo Pastorello, Alexander Husband, Judy E. Garber, Diane Weber, Isabelle Bedrosian, Eileen Dimond, Malgorzata Wojtowicz, Brandy M. Heckman-Stoddard, Na Qiao, Guy T. Clifton, Anne E. O'Shea
Supplementary Table S5: HER2 expression in biopsy and resection specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1943aef419ca844e93810d26a9c95bd6
https://doi.org/10.1158/1940-6207.22806877.v1
https://doi.org/10.1158/1940-6207.22806877.v1
Autor:
Elizabeth A. Mittendorf, George E. Peoples, Gheath Alatrash, Powel H. Brown, Lana A. Vornik, Diane D. Liu, Mike Hernandez, J. Jack Lee, Ricardo Pastorello, Alexander Husband, Judy E. Garber, Diane Weber, Isabelle Bedrosian, Eileen Dimond, Malgorzata Wojtowicz, Brandy M. Heckman-Stoddard, Na Qiao, Guy T. Clifton, Anne E. O'Shea
Supplementary Fig. S1: Nelipepimut-S (NPS)-specific cytotoxic T lymphocyte (CTL) responses in patients receiving NeuVax with corresponding HER2 changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e59b72fc42e69fd9132efc0311f9f74
https://doi.org/10.1158/1940-6207.22806895.v1
https://doi.org/10.1158/1940-6207.22806895.v1
Autor:
Anne E. O’Shea, Phillip M. Kemp Bohan, Elizabeth L. Carpenter, Patrick M. McCarthy, Alexandra M. Adams, Robert C. Chick, Julia O. Bader, Robert W. Krell, George E. Peoples, Guy T. Clifton, Daniel W. Nelson, Timothy J. Vreeland
Publikováno v:
Annals of Surgical Oncology. 29:6015-6028
Autor:
Michael A. Liss, George E. Peoples, Ian M. Thompson, Vance Y. Sohn, Guy T. Clifton, Diane Hale, Daniel C. Ensley, Jessica L. Cindass, Annelies T. Hickerson, Timothy J. Vreeland, Anne E. O'Shea, Robert C. Chick, Phillip M. Kemp Bohan
No approved medical therapies prevent progression of low-grade prostate cancer. Rapamycin inhibits cell proliferation and augments immune responses, producing an antitumor effect. Encapsulated rapamycin (eRapa) incorporates rapamycin into a pH-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df6fe3a77c48c9cc83d03822502f1e9
https://doi.org/10.1158/1940-6207.c.6547112
https://doi.org/10.1158/1940-6207.c.6547112