Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Guy Surpris"'
Autor:
Varea H. Costello, Sara L. Robinson, Seth Klusewitz, Guy Surpris, Md Nahid, Michael G. Backlund
Publikováno v:
Access Microbiology. 4
Introduction. Haemophilus species are gram-negative, non-motile, facultative anaerobic coccobacilli in the larger family of Pasteurellaceae . Implicated in a variety of human diseases, Haemophilus species are also included in the ‘HACEK’ group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c00db668509ef284d6fb5a6c74001d86
https://doi.org/10.1099/acmi.0.000410
https://doi.org/10.1099/acmi.0.000410
Autor:
Alexander Poltorak, Guy Surpris
Publikováno v:
Current Opinion in Microbiology
The identification and characterization of DNA-sensing pathways has been a subject of intensive investigation for the last decade. This interest, in part, is supported by the fact that the main outcome of DNA-responses is production of type I interfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861ecd9427989f011f3c6a0041ef031c
Autor:
Maninjay K. Atianand, Katherine A. Fitzgerald, Jennie Chan, Tatyana O. Volkova, Beiyun C. Liu, Alexander Poltorak, Shrutie Sharma, Mikayla R. Thompson, Vladimir Ilyukha, Irina Smirnova, Guy Surpris
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(2)
With the stimulator of IFN genes (STING) C terminus being extensively studied, the role of the N-terminal domain (NTD) of STING remains an important subject of investigation. In this article, we identify novel mutations in NTD of Sting of the MOLF st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a2fbd256d8eb7a58f8f64f18ee2902
https://pubmed.ncbi.nlm.nih.gov/26685207
https://pubmed.ncbi.nlm.nih.gov/26685207
Autor:
Tatyana O. Volkova, Guy Surpris, Alexander Poltorak, Vladimir Ilyukha, Olga V. Kurmyshkina, Bridget Larkin
Publikováno v:
Cytokine. 76:78-79
The cytoplasmic protein Stimulator of Interferon Genes (STING) plays an essential role in sensing cytoplasmic DNA of intracellular pathogens and initiating IFN type I responses in myeloid cells. It can also directly bind cyclic dinucleotides produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc8485706da3700124f20529e87bed1
https://doi.org/10.1016/j.cyto.2015.08.103
https://doi.org/10.1016/j.cyto.2015.08.103
Publikováno v:
The Journal of Immunology. 194:59.8-59.8
The cytoplasmic protein Stimulator of Interferon Genes (STING) plays an essential role in sensing intracellular pathogens and initiating type I IFN responses in myeloid cells. STING detects the presence of cytoplasmic DNA presented by various DNA-bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65071e82be4eb03a1c8597c1efd13f92
https://doi.org/10.4049/jimmunol.194.supp.59.8
https://doi.org/10.4049/jimmunol.194.supp.59.8
Publikováno v:
The Journal of Immunology. 190:112.34-112.34
We identified a novel phenotype in wild derived inbred mouse strain, MOLF/EiJ (MOLF). In response to cytosolic DNA or cyclic-diadenylate (c-di-AMP), MOLF macrophages exhibit high levels of IL-6 but very low levels of type I interferon, IFNβ, compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::661897a71e7f0d6f70359f3614134603
https://doi.org/10.4049/jimmunol.190.supp.112.34
https://doi.org/10.4049/jimmunol.190.supp.112.34