Fractional Flow Reserve Evaluated as Metric of Coronary Stenosis — A Mathematical Model Study

Autor: Theo J. C. Faes, Romain Meer, Guy R. Heyndrickx, Peter L. M. Kerkhof

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 6 (2020)

Introduction: Coronary arterial stenosis may impair myocardial perfusion with myocardial ischemia and associated morbidity and mortality as result. The myocardial fractional flow reserve (FFR) is clinically used as a stenosis-specific index.Aim: This

Externí odkaz: https://doaj.org/article/6eb33a38ff52494fb7d88bad855fa21b

Time-Dependent Effects on Coronary Remodeling and Epicardial Conductance after Intracoronary Injection of Enriched Hematopoietic Bone Marrow Stem Cells in Patients with Previous Myocardial Infarction

Autor: Marc Vanderheyden, Steven Vercauteren, Samer Mansour, Leen Delrue, Bart Vandekerckhove, Guy R. Heyndrickx, Inge Van Haute, Bernard De Bruyne, Frank Timmermans, William Wijns, Jozef Bartunek

Publikováno v: Cell Transplantation, Vol 16 (2007)

Bone marrow (BM) cells may interact with coronary endothelium and modulate coronary atherosclerosis. We investigated the time course of coronary luminal loss and changes in conductance after intracoronary injection of enriched hematopoietic BM stem c

Externí odkaz: https://doaj.org/article/43cdbbb2124b459c90588e0dd9ac8f44

[A critical analysis of ejection fraction]

Autor: Peter Lm, Kerkhof, Rienzi, Díaz-Navarro, Guy R, Heyndrickx, Neal, Handly

Publikováno v: Revista medica de Chile. 150(2)

Ejection fraction (EF) is defined by the ratio of end-systolic volume (ESV) and end-diastolic volume (EDV). The resulting fraction is a dimensionless number whose interpretation is ambiguous and most likely misleading. Despite this limitation, EF is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::17a7c0212c1c73181f219d099090a534
https://pubmed.ncbi.nlm.nih.gov/36156650

Cardiopoietic stem cell therapy in ischaemic heart failure: long-term clinical outcomes

Autor: Gerasimos Filippatos, Marco Metra, Warren Sherman, Chart Program, John R. Teerlink, William Wijns, Michal Tendera, Guy R. Heyndrickx, Roger J. Hajjar, Andre Terzic, Ricardo Sanz-Ruiz, Jozef Bartunek, Stefanie Senger, Gad Cotter, Atta Behfar, Wojciech Wojakowski, Scott A. Waldman, Thomas J. Povsic, Timothy D. Henry, Beth A. Davison, Bernard J. Gersh

Publikováno v: ESC Heart Failure
ESC Heart Failure, Vol 7, Iss 6, Pp 3345-3354 (2020)

Aims This study aims to explore long‐term clinical outcomes of cardiopoiesis‐guided stem cell therapy for ischaemic heart failure assessed in the Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART‐1) trial. Methods and results C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22e96fa0d926cc2ccd78d2d633b4f85
https://pubmed.ncbi.nlm.nih.gov/33094909

The Pythagorean theorem reveals the inherent companion of cardiac ejection fraction

Autor: Jean Paul Merillon, Richard A. Peace, Guy R. Heyndrickx, Peter L. M. Kerkhof, Neal Handly, Lilian J. Meijboom, Ralf W. Sprengers, Gareth Parry, Han Ki Park, Byung Won Yoo, Tatiana Kuznetsova

Publikováno v: Kerkhof, P L M, Mérillon, J P, Yoo, B W, Peace, R A, Parry, G, Heyndrickx, G R, Kuznetsova, T, Meijboom, L J, Sprengers, R W, Park, H K & Handly, N 2018, ' The Pythagorean theorem reveals the inherent companion of cardiac ejection fraction ', International Journal of Cardiology, vol. 270, pp. 237-243 . https://doi.org/10.1016/j.ijcard.2018.06.074, https://doi.org/10.1016/j.ijcard.2018.06.074
International Journal of Cardiology, 270, 237-243. Elsevier Ireland Ltd

BACKGROUND: Quantification of ventricular performance requires a comprehensive metric which is manageable for patient care and clinical trials. Ejection fraction (EF) has been embraced as an attractive candidate. However, being a dimensionless ratio,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82507d5277ab4f4982e8dcbf905c8e10
https://doi.org/10.1016/j.ijcard.2018.06.074