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Identification of Amino Acids in Trm734 Required for 2'- O -Methylation of the tRNA ^Phe Wobble Residue.

Autor: Funk HM; Department of Chemistry & Biochemistry, Dorothy Westerman Herrmann Science Center (SC), Room 204F, Northern Kentucky University, Highland Heights, Kentucky 41076, United States of America., Brooks JH; Department of Chemistry & Biochemistry, Dorothy Westerman Herrmann Science Center (SC), Room 204F, Northern Kentucky University, Highland Heights, Kentucky 41076, United States of America., Detmer AE; Department of Chemistry & Biochemistry, Dorothy Westerman Herrmann Science Center (SC), Room 204F, Northern Kentucky University, Highland Heights, Kentucky 41076, United States of America., Creech NN; Department of Chemistry & Biochemistry, Dorothy Westerman Herrmann Science Center (SC), Room 204F, Northern Kentucky University, Highland Heights, Kentucky 41076, United States of America., Guy MP; Department of Chemistry & Biochemistry, Dorothy Westerman Herrmann Science Center (SC), Room 204F, Northern Kentucky University, Highland Heights, Kentucky 41076, United States of America.

Publikováno v: ACS omega [ACS Omega] 2024 Jun 03; Vol. 9 (23), pp. 25063-25072. Date of Electronic Publication: 2024 Jun 03 (Print Publication: 2024).

Identification of the enzymes responsible for m2,2G and acp3U formation on cytosolic tRNA from insects and plants.

Autor: Funk HM; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America., Zhao R; Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, United States of America., Thomas M; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America., Spigelmyer SM; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America., Sebree NJ; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America., Bales RO; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America., Burchett JB; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America., Mamaril JB; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America., Limbach PA; Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, Ohio, United States of America., Guy MP; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, United States of America.

Publikováno v: PloS one [PLoS One] 2020 Nov 30; Vol. 15 (11), pp. e0242737. Date of Electronic Publication: 2020 Nov 30 (Print Publication: 2020).

Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA.

Autor: Payea MJ; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA., Sloma MF; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA., Kon Y; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA., Young DL; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Guy MP; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA., Zhang X; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA., De Zoysa T; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA., Fields S; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.; Department of Medicine, University of Washington, Seattle, Washington 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, Washington 98195, USA., Mathews DH; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA., Phizicky EM; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York 14642, USA.

Publikováno v: RNA (New York, N.Y.) [RNA] 2018 Mar; Vol. 24 (3), pp. 410-422. Date of Electronic Publication: 2017 Dec 19.

Mutation in WDR4 impairs tRNA m(7)G46 methylation and causes a distinct form of microcephalic primordial dwarfism.

Autor: Shaheen R; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Abdel-Salam GM; Clinical Genetics Department, Human Genetics and Genome Research Division, National Research Centre, Cairo, Egypt., Guy MP; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.; Current address: Department of Chemistry, Northern Kentucky University, Highland Heights, KY, USA., Alomar R; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Abdel-Hamid MS; Medical Molecular Genetics Department, Human Genetics and Genome Research Division, National Research Centre, Cairo, Egypt., Afifi HH; Clinical Genetics Department, Human Genetics and Genome Research Division, National Research Centre, Cairo, Egypt., Ismail SI; Clinical Genetics Department, Human Genetics and Genome Research Division, National Research Centre, Cairo, Egypt., Emam BA; Clinical Genetics Department, Human Genetics and Genome Research Division, National Research Centre, Cairo, Egypt., Phizicky EM; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. Eric_Phizicky@URMC.Rochester.edu., Alkuraya FS; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. falkuraya@Kfshrc.edu.sa.; Department of Anatomy and Cell Biology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia. falkuraya@Kfshrc.edu.sa.

Publikováno v: Genome biology [Genome Biol] 2015 Sep 28; Vol. 16, pp. 210. Date of Electronic Publication: 2015 Sep 28.