Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Guy Leclercq"'
Autor:
Guy Leclercq
Publikováno v:
Endocrines, Vol 5, Iss 1, Pp 102-115 (2024)
The evolution of breast cancers results from the emergence of epithelial cell subpopulations containing variant Estrogen Receptor α which is able to bypass conventional treatments aimed at antagonizing the activity of this tumor-promoting receptor.
Externí odkaz:
https://doaj.org/article/22da2c12ebdf40ccbbad3047f19c2d85
Autor:
Philipp Y. Maximov, Guy Leclercq
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/cd736ed383f54b718425aff2ffd01ef5
Autor:
Guy Leclercq, Filippo Acconcia
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/eb45451f95a440c385e9512197c044a5
Autor:
Guy Leclercq
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 411 (2018)
The detection of human anti-estrogen receptor α antibodies (ERαABs) inducing estrogenic responses in MCF-7 mammary tumor cells suggests their implication in breast cancer emergence and/or evolution. A recent report revealing a correlation between t
Externí odkaz:
https://doaj.org/article/7fb7521def5844e49f3b8c739b31a0c1
Autor:
Guy Leclercq
Publikováno v:
Endocrines. 2:1-14
Estrogen receptor alpha (ERα) is a modulator of breast cancer maintenance and evolution. Hence, analysis of underlying mechanisms by which ERα operates is of importance for the improvement of the hormonal therapy of the disease. This review focuses
Publikováno v:
European Journal of Pharmaceutical Sciences, Vol. 109 (2017) pp. 169-181
The synthetic coumestrol derivative 6,12-dihydro-3-methoxy-1-benzopyrano[3,4-b][1,4]benzothiazin-6-one (estrothiazine, ESTZ) has been identified as a weak estrogen receptor α (ERα) ligand unable to compete with tritiated estradiol. The biological a
Autor:
Guy Leclercq
Depuis la première traduction en français du premier des "livres d'Alice" de Lewis Carroll, l'accueil de la petite héroïne a connu (et connaît encore) deux qualités de réception distinctes. La principale raison de cette opposition tient probab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ce79617fc6fd0d7393c0c76ab558e0
http://palimpsestes.revues.org/679
http://palimpsestes.revues.org/679
Autor:
Guy Leclercq
Rire est le propre de l'homme, dit-on, mais qu'y a-t-il de commun entre le rire d'un Suedois et celui d'un Pygmee ? Ce qui fait rire un Japonais ne fait pas (obligatoirement) rire un Lapon. Faire rire un Francais avec les textes qui font rire un Angl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdcc671243fde804eea996ce03e34d4
http://palimpsestes.revues.org/760
http://palimpsestes.revues.org/760
Autor:
Yves Jacquot, Emeric Miclet, Maria-Eleni Kampa, Elias Castanas, Cillian Byrne, Vasiliki Pelekanou, Dominique Gallo, Guy Leclercq, Isabelle Broutin
Publikováno v:
Chirality. 25:628-642
Protein-protein interactions are crucial for signal transductions required for cell differentiation and proliferation. Their modulation is therefore key to the development of therapeutic alternatives, particularly in the context of cancer. According
Autor:
Efstathios N. Stathopoulos, George Notas, Jelena Radojicic, Guy Leclercq, Elias Castanas, Eleftheria Tsentelierou, Marilena Kampa, Vasiliki Pelekanou
Publikováno v:
Steroids. 77:928-934
Triple negative breast cancer is deprived of estrogen receptor alpha (ERα), progesterone receptor (PR) and HER-2 protein. It constitutes the most heterogeneous and aggressive group of breast carcinomas, for which identification of novel characterist