Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Guy Lagaud"'
Autor:
Georges J. Nahhas, K. Michael Cummings, Michael J. Halenar, Eva Sharma, Anthony J. Alberg, Dorothy Hatuskami, Maansi Bansal-Travers, Andrew Hyland, Diann E. Gaalema, Pamela B. Morris, Kara Duffy, Joanne T. Chang, Guy Lagaud, Juan C. Vivar, Daniela Marshall, Carlos Blanco, Kristie A. Taylor
Publikováno v:
Preventive Medicine Reports, Vol 25, Iss , Pp 101650- (2022)
The purpose of this period prevalence study is to compare the prevalence of cardiovascular disease (CVD) in current/former established smokeless tobacco (SLT) users (ever SLT users who have used the product fairly regularly) to those who were: 1) nev
Externí odkaz:
https://doaj.org/article/5fae1e6d012d4dc690dfcf03222bd719
Autor:
Steven B Yee, Wei Ding, Mason G. Pearce, Shu-Chieh Hu, Roberta A. Mittelstaedt, Raul A. Trbojevich, Susan Chemerynski, Melis Coraggio, R. Philip Yeager, Sherry M. Lewis, Hans Rosenfeldt, Yunan Tang, Guy Lagaud, Kelly Davis, Matthew Bryant, Estatira Sepehr, Michelle E. Bishop, Darshan Mehta, Hyun-Ki Kang, Paul C. Howard
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 182(1)
The tobacco-specific nitrosamine NNK [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone] is found in tobacco products and tobacco smoke. NNK is a potent genotoxin and human lung carcinogen; however, there are limited inhalation data for the toxicokineti
Autor:
Dana M. van Bemmel, Kimberly M. Capella, Guy Lagaud, Andrew Hyland, Eva Sharma, Joanne T. Chang, Luyu Zhang, Christopher M. Reese, Heather L. Kimmel, Deepak Bhandari, Maciej L. Goniewicz, Benjamin C. Blount, Arseima Y. Del Valle-Pinero, Denise S. Tevis, Víctor R. De Jesús, Wanzhe Zhu
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 17
Issue 15
International Journal of Environmental Research and Public Health, Vol 17, Iss 5408, p 5408 (2020)
Volume 17
Issue 15
International Journal of Environmental Research and Public Health, Vol 17, Iss 5408, p 5408 (2020)
Volatile organic compounds (VOCs) are ubiquitous in the environment. In the United States (U.S.), tobacco smoke is the major non-occupational source of exposure to many harmful VOCs. Exposure to VOCs can be assessed by measuring their urinary metabol
Autor:
Jiashi Wang, John D. Baird, Neil Gregory Almstead, Marla Weetall, Yi Jin Kim Gorske, Jean Hedrick, Jana Narasimhan, Aleksey I. Gerasyuto, Tamil Arasu, Srinivasa Peddi, Wu Du, Michael Arnold, Josephine Sheedy, Gary Mitchell Karp, Stanley W. Lue, Guy Lagaud, Arthur Branstrom, J. V. N. Vara Prasad, Ginzburg Olya
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(22)
The continued emergence of bacteria resistant to current standard of care antibiotics presents a rapidly growing threat to public health. New chemical entities (NCEs) to treat these serious infections are desperately needed. Herein we report the disc
Autor:
P Wagaman, Michele C. Rizzolio, Magda F. Morton, L Andries, Terrance D Barrett, Nigel P. Shankley, Guy Lagaud, W Yan, JM Freedman
Publikováno v:
British Journal of Pharmacology. 166:1684-1693
BACKGROUND AND PURPOSE JNJ-26070109 [(R)4-bromo-N-[1-(2,4-difluoro-phenyl)-ethyl]-2-(quinoxaline-5-sulfonylamino)-benzamide] is a novel antagonist at cholecystokinin CCK2 receptors with good pharmacokinetic properties and represents a novel mechanism
Autor:
James Guy Breitenbucher, Nigel P. Shankley, Jamie M. Freedman, Terrance D. Barrett, Guy Lagaud, Wen Yan
Publikováno v:
British Journal of Pharmacology. 153:1650-1658
Background and purpose: Cholecystokinin (CCK) stimulates the release of amylase and lipase from the normal pancreas. However, it is not clear to what extent this occurs in the early stages of pancreatitis induced by biliary tract obstruction in the r
Publikováno v:
Biochemical and Biophysical Research Communications. 357:264-269
Obestatin was recently described as a bioactive peptide encoded for by the same gene as ghrelin but with opposite actions on food intake. Although some groups have confirmed these findings others find no effect. We investigated the effect of obestati
Autor:
Stephen M. Factor, Amanda North, William Schubert, Robert G. Russell, Michelle W.-C. Cheung, Guy Lagaud, George J. Christ, Moses Tarr, Ghada. S. Hassan, Michael P. Lisanti, Carolyn Marks, Scott Eric Woodman
Publikováno v:
Journal of Urology. 171:950-957
Caveolae are flask-shaped invaginations of the plasma membrane formed by the oligomerization of caveolins. Because only smooth muscle contains all caveolin (Cav) family members (Cav-1, 2 and 3), we examined the contribution of each caveolin to urogen
Publikováno v:
Scopus-Elsevier
Pressure-induced decreases in arterial diameter are accompanied by membrane depolarization and Ca2+ entry via voltage-gated Ca2+ channels. Recent evidence also suggests the involvement of Ca2+ sensitization of the contractile proteins. Both PKC and R
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 283:H2177-H2186
The effects of two structurally distinct inhibitors of gap junction communication were studied by using three different forms of vasoconstriction in pressurized rat middle cerebral arteries. The sensitivity of myogenic tone (at 60 mmHg), vasopressin-