Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Guy L Reed"'
Autor:
Dong Wang, Inna P Gladysheva, Ryan D Sullivan, Tai-Hwang M Fan, Radhika M Mehta, Ranjana Tripathi, Yao Sun, Guy L Reed
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202571 (2018)
Following acute myocardial infarction, clinical studies show alterations in the blood levels of corin, a cardiac-selective activator of the natriuretic peptides pro-atrial natriuretic peptide (pro-ANP) and pro-B-type natriuretic peptide (pro-BNP). Ho
Externí odkaz:
https://doaj.org/article/c9fda0ea9f56490eb445b966eb1c9441
Autor:
Ranjana Tripathi, Ryan Sullivan, Tai-Hwang M Fan, Dong Wang, Yao Sun, Guy L Reed, Inna P Gladysheva
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189315 (2017)
Dilated cardiomyopathy (DCM) is the major cause of heart failure affecting both women and men. Limited clinical studies show conflicting data in sex-related differences in the progression of dilated cardiomyopathy and heart failure (HF) outcomes. We
Externí odkaz:
https://doaj.org/article/f219182b93c74df8a117d025d50d5526
Autor:
Benjamin R Zambetti, Fridtjof Thomas, Inyong Hwang, Allen C Brown, Mason Chumpia, Robert T Ellis, Darshan Naik, Rami N Khouzam, Uzoma N Ibebuogu, Guy L Reed
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181658 (2017)
In ST-elevation myocardial infarction (STEMI), acute kidney injury (AKI) may increase subsequent morbidity and mortality. Still, it remains difficult to predict AKI risk in these patients. We sought to 1) determine the frequency and clinical outcomes
Externí odkaz:
https://doaj.org/article/21203161a7354ba9a1ec260e817a1466
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9442 (2024)
Matrix metalloproteinases (MMPs) such as MMP-9, 3, and 2 degrade the cellular matrix and are believed to play a crucial role in ischemic stroke. We examined how the duration of ischemia (up to 4 h) and treatment with recombinant tissue plasminogen ac
Externí odkaz:
https://doaj.org/article/bfc0ae37e87849c0a0616587d8d3dbec
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/7a7ef71ef1c44048a1cd82c89110dd82
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Alpha2-antiplasmin (α2AP), the fast-reacting, serine protease inhibitor (serpin) of plasmin, was originally thought to play a key role in protection against uncontrolled, plasmin-mediated proteolysis of coagulation factors and other molecules. Howev
Externí odkaz:
https://doaj.org/article/bb5fa8027a0543c088a4d67b8a6c7d9e
Autor:
Ranjana Tripathi, Ryan D. Sullivan, Tai-Hwang M. Fan, Radhika M. Mehta, Inna P. Gladysheva, Guy L. Reed
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4035 (2021)
Sodium restriction is often recommended in heart failure (HF) to block symptomatic edema, despite limited evidence for benefit. However, a low-sodium diet (LSD) activates the classical renin-angiotensin-aldosterone system (RAAS), which may adversely
Externí odkaz:
https://doaj.org/article/446661050e01445781a22a4b2e978e26
Autor:
Oluwaseyi Bolorunduro, Blake Smith, Mason Chumpia, Poojitha Valasareddy, Mark R. Heckle, Rami N. Khouzam, Guy L. Reed, Uzoma N. Ibebuogu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 10 (2016)
BackgroundThere are poorer outcomes following ST elevation myocardial infarction in blacks compared to white patients despite comparable door‐to‐reperfusion time. We hypothesized that delays to hospital presentation may be contributory. Methods a
Externí odkaz:
https://doaj.org/article/535c18c75b8a42ab92b980b352f4c3a8
Autor:
Farouc A. Jaffer, Michael R. Jaff, Guy L. Reed, Lang Wang, Hang Lee, Chase W. Kessinger, Ido Weinberg, Wenzhu Li, Peter Libby, Ahmed Tawakol, Peter K. Henke, Makoto Orii
Publikováno v:
Circulation
Background: Up to 50% of patients with proximal deep vein thrombosis (DVT) will develop the postthrombotic syndrome characterized by limb swelling and discomfort, hyperpigmentation, skin ulcers, and impaired quality of life. Although catheter-based i
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3886 (2019)
Heart failure (HF) patients frequently have elevated plasma renin activity. We examined the significance of elevated plasma renin activity in a translationally-relevant model of dilated cardiomyopathy (DCM), which replicates the progressive stages (A
Externí odkaz:
https://doaj.org/article/d20c731370e845bb8ecb02627dd0ce29