Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Guy Healing"'
Publikováno v:
Archives of toxicology. 93(3)
Cyclin-dependent kinases (CDKs) are a family of kinases associated predominantly with cell cycle control, making CDK inhibitors interesting candidates for anti-cancer therapeutics. However, retinal toxicity (loss of photoreceptors) has been associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c43ce6c3f6dbe42c3d48c2d8dcdf612
https://pubmed.ncbi.nlm.nih.gov/30617560
https://pubmed.ncbi.nlm.nih.gov/30617560
Autor:
Tabassum Sulemann, Clare Garner, Rowena Finney, Lisa D. Burdett, Carolin Schramm, Jayne Harris, Guy Healing, Perrine Pivette, Peter Cotton, Adam Hargreaves, Sarah Kirk
Publikováno v:
Journal of Applied Toxicology. 36:140-150
Potential new drugs are assessed in pre-clinical in vivo studies to determine their safety profiles. The drugs are formulated in vehicles suitable for the route of administration and the physicochemical properties of the drug, aiming to achieve optim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253fe13cae15abf9c394854f0c93836d
https://doi.org/10.1002/jat.3155
https://doi.org/10.1002/jat.3155
Autor:
Juliana Maynard, Stewart Davis, Marietta Scott, Sally-Ann Ricketts, Andrew P. Holmes, Angela Sykes, Helen Powell, Jane Stewart, Guy Healing
Publikováno v:
Journal of Applied Toxicology. 34:1368-1372
The lens is formed in utero with new secondary lens fibres added as outer layers throughout life in a growth pattern characteristic of the species. This study examined the time course of beagle lens growth to better understand the optimal starting ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114dd9cccc0de05943f73acedf45a2f4
https://doi.org/10.1002/jat.2967
https://doi.org/10.1002/jat.2967
Autor:
Owen P. Green, Guy Healing
Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity
Autor:
Owen P. Green, Guy Healing
Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity
Autor:
Owen P. Green, Guy Healing
Intravenous infusion is a necessary mode of delivery for many pharmaceuticals currently on the market or undergoing clinical trials. The technique of prolonged intravenous delivery in conscious, free-moving animal models has broadened the opportunity
Autor:
Guy, Healing, Tabassum, Sulemann, Peter, Cotton, Jayne, Harris, Adam, Hargreaves, Rowena, Finney, Sarah, Kirk, Carolin, Schramm, Clare, Garner, Perrine, Pivette, Lisa, Burdett
Publikováno v:
Journal of applied toxicology : JAT. 36(1)
Potential new drugs are assessed in pre-clinical in vivo studies to determine their safety profiles. The drugs are formulated in vehicles suitable for the route of administration and the physicochemical properties of the drug, aiming to achieve optim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b2e1d2720c46a7f24294914103b6524
https://pubmed.ncbi.nlm.nih.gov/25959454
https://pubmed.ncbi.nlm.nih.gov/25959454
Autor:
Owen P. Green, Guy Healing
Publikováno v:
Non-Clinical Vascular Infusion Technology, Two Volume Set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79b864ed625a8981e5274b9ba050092a
https://doi.org/10.1201/b16370
https://doi.org/10.1201/b16370
Autor:
Guy Healing, Owen P. Green
Publikováno v:
Non-Clinical Vascular Infusion Technology, Volume II: The Techniques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b311c2c2c6c0112ece3cc398b6a19dda
https://doi.org/10.1201/b16151
https://doi.org/10.1201/b16151