Zobrazeno 1 - 10 of 60 pro vyhledávání: '"Guy H. Grant"'
1
Akademický článek
The Role of CDK4 in the Pathogenesis of Pancreatic Cancer
Autor: Emily Jiggens, Maria Mortoglou, Guy H. Grant, Pinar Uysal-Onganer
Publikováno v: Healthcare, Vol 9, Iss 11, p 1478 (2021)
Pancreatic cancer (PC) continues to have the lowest overall survival and the lack of effective early diagnosis. Cyclin-dependent kinase 4 (CDK4) plays a fundamental role in the orderly progression of the cell cycle, binding to cyclin D to promote the
Externí odkaz: https://doaj.org/article/89a39525326943deba1f1cb57e8fdadd
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2
Akademický článek
MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species
Autor: Sigrun Lange, Elif Damla Arisan, Guy H. Grant, Pinar Uysal-Onganer
Publikováno v: Viruses, Vol 13, Iss 1, p 117 (2021)
Our recent study identified seven key microRNAs (miR-8066, 5197, 3611, 3934-3p, 1307-3p, 3691-3p, 1468-5p) similar between SARS-CoV-2 and the human genome, pointing at miR-related mechanisms in viral entry and the regulatory effects on host immunity.
Externí odkaz: https://doaj.org/article/43c6d5b21d794ec98bf9245a3df85c97
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3
Akademický článek
The Prediction of miRNAs in SARS-CoV-2 Genomes: hsa-miR Databases Identify 7 Key miRs Linked to Host Responses and Virus Pathogenicity-Related KEGG Pathways Significant for Comorbidities
Autor: Elif Damla Arisan, Alwyn Dart, Guy H. Grant, Serdar Arisan, Songul Cuhadaroglu, Sigrun Lange, Pinar Uysal-Onganer
Publikováno v: Viruses, Vol 12, Iss 6, p 614 (2020)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the betacoronavirus family, which causes COVID-19 disease. SARS-CoV-2 pathogenicity in humans leads to increased mortality rates due to alterations of significant pathways, i
Externí odkaz: https://doaj.org/article/506d13d0f00846f69e5af170ecaf718f
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4
Akademický článek
Inhibition on JNK Mimics Silencing of Wnt-11 Mediated Cellular Response in Androgen-Independent Prostate Cancer Cells
Autor: Elif Damla Arisan, Ozge Rencuzogullari, Buse Keskin, Guy H. Grant, Pinar Uysal-Onganer
Publikováno v: Biology, Vol 9, Iss 7, p 142 (2020)
Prostate cancer (PCa) is one of the most common cancers among men, and one of the leading causes of cancer death for men. The c-Jun N-terminal kinase (JNK) pathway is required for several cellular functions, such as survival, proliferation, different
Externí odkaz: https://doaj.org/article/6b366b30273f4a2cb24268982792e572
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6
The Role of CDK4 in the Pathogenesis of Pancreatic Cancer
Autor: Guy H. Grant, Emily Jiggens, Pinar Uysal-Onganer, Maria Mortoglou
Publikováno v: Healthcare, Vol 9, Iss 1478, p 1478 (2021)
Healthcare
Volume 9
Issue 11
Pancreatic cancer (PC) continues to have the lowest overall survival and the lack of effective early diagnosis. Cyclin-dependent kinase 4 (CDK4) plays a fundamental role in the orderly progression of the cell cycle, binding to cyclin D to promote the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9967649bf58a391d653ce39e6f3d39c6
https://www.mdpi.com/2227-9032/9/11/1478
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7
MicroRNAs for Virus Pathogenicity and Host Responses, Identified in SARS-CoV-2 Genomes, May Play Roles in Viral-Host Co-Evolution in Putative Zoonotic Host Species
Autor: Guy H. Grant, Pinar Uysal-Onganer, Elif Damla Arisan, Sigrun Lange
Publikováno v: Viruses
Volume 13
Issue 1
Viruses, Vol 13, Iss 117, p 117 (2021)
Our recent study identified seven key microRNAs (miR-8066, 5197, 3611, 3934-3p, 1307-3p, 3691-3p, 1468-5p) similar between SARS-CoV-2 and the human genome, pointing at miR-related mechanisms in viral entry and the regulatory effects on host immunity.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04dc883760a89babc3a18e480bac532
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8
Inhibition on JNK Mimics Silencing of Wnt-11 Mediated Cellular Response in Androgen-Independent Prostate Cancer Cells
Autor: Buse Keskin, Ozge Rencuzogullari, Pinar Uysal-Onganer, Elif Damla Arisan, Guy H. Grant
Publikováno v: Biology
Volume 9
Issue 7
Biology, Vol 9, Iss 142, p 142 (2020)
Prostate cancer (PCa) is one of the most common cancers among men, and one of the leading causes of cancer death for men. The c-Jun N-terminal kinase (JNK) pathway is required for several cellular functions, such as survival, proliferation, different
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3597ad5df1e19de770aa9c2eb83d4d16
https://doi.org/10.3390/biology9070142
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9
The interaction of Wnt-11 and signalling cascades in prostate cancer
Autor: Guy H. Grant, Pinar Uysal-Onganer, Sarah Koushyar
Publikováno v: Tumor Biology. 37:13049-13057
Prostate cancer (PCa) is the second most common cancer among the male population. Conventional therapies target androgen signalling, which drives tumour growth; however, they provide limited survival benefits for patients. It is essential, therefore,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bce713fb40f6dcc6fe2cee34126b0e3
https://doi.org/10.1007/s13277-016-5263-z
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10
Modelling, inference and big data in biophysics
Autor: Guy H. Grant, Joshua W. K. Ho
In recognition of the increasing importance of big data in biophysics, a new session called ‘Modelling, inference, big data’ is incorporated into the IUPAB/EBSA Congress on 18 July 2017 at Edinburgh, UK.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b4c39f0e34dc8cb2df361cae55eb30
https://europepmc.org/articles/PMC5578925/
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