Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Guy Gloor"'
Autor:
Alicia V. Duran-Capece, Jamie M. McCabe Dunn, George T. F. Wong, Brendan Meehan, Guy Gloor, Tetsuo Iwama, James Ulis, Evan J. Bekos
Publikováno v:
Organic Process Research & Development. 15:1442-1446
Sodium hydride was found to be the best base for a displacement reaction on a chloropyrimidine. Due to the insolubility of sodium hydride in all solvents and high reactivity with atmospheric moisture, solutions dealing with the associated safety conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9606f2856f9be775e2cd13141d56dc4
https://doi.org/10.1021/op200114t
https://doi.org/10.1021/op200114t
Autor:
Aleksey Zaks, Guy Gloor, James Lalonde, Ben Mijts, George T. F. Wong, Matt Tobin, Gjalt W. Huisman, Sheela Muley, Xiyun Zhang, Alexandre Ambrogelly, Azzeddine Lekhal, Tao Li, Tim Brennan, Jack Liang, Lisa M. Newman
Publikováno v:
Journal of the American Chemical Society. 134(14)
The key structural feature in Boceprevir, Merck’s new drug treatment for hepatitis C, is the bicyclic [3.1.0]proline moiety “P2”. During the discovery and development stages, the P2 fragment was produced by a classical resolution approach. As t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639368693bf55a033f423505010bd9bf
https://pubmed.ncbi.nlm.nih.gov/22409428
https://pubmed.ncbi.nlm.nih.gov/22409428
The Safe Use of Sodium Hydride on Scale: The Process Development of a Chloropyrimidine Displacement.
Autor:
Jamie M. McCabe Dunn, Alicia Duran-Capece, Brendan Meehan, James Ulis, Tetsuo Iwama, Guy Gloor, George Wong, Evan Bekos
Publikováno v:
Organic Process Research & Development; Nov2011, Vol. 15 Issue 6, p1442-1446, 5p