Zobrazeno 1 - 10
of 453
pro vyhledávání: '"Guy E. Thwaites"'
Autor:
Liane S. Canas, Trinh H. K. Dong, Daniel Beasley, Joseph Donovan, Jon O. Cleary, Richard Brown, Nguyen Thuy Thuong Thuong, Phu Hoan Nguyen, Ha Thi Nguyen, Reza Razavi, Sebastien Ourselin, Guy E. Thwaites, Marc Modat, the Vietnam ICU Translational Applications Laboratory (VITAL) Investigators
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. Clinical features, such as coma, can predict death, but they are insufficient for the accurate prognosis of other outcomes, especially when impacted by co-morbidities such
Externí odkaz:
https://doaj.org/article/08a080fc43a44141b75690f09cfec498
Autor:
Ruan Spies, Hanh N. Hong, Phu P. Trieu, Luong K. Lan, Kim Lan, N.N. Hue, Nguyen T.L. Huong, Tran T.L.N. Thao, Nguyen L. Quang, Thu D.D. Anh, Truong V. Vinh, Dang T.M. Ha, Phan T. Dat, Nguyen P. Hai, Le H. Van, Guy E. Thwaites, Nguyen T.T. Thuong, James A. Watson, Timothy M. Walker
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 3, Pp 499-509 (2024)
We characterized the spatial distribution of drug-susceptible (DS) and multidrug-resistant (MDR) tuberculosis (TB) cases in Ho Chi Minh City, Vietnam, a major metropolis in southeastern Asia, and explored demographic and socioeconomic factors associa
Externí odkaz:
https://doaj.org/article/e118477f0ba44082be8d6d00985f8e70
Autor:
Trinh Huu Khanh Dong, Joseph Donovan, Nghiem My Ngoc, Do Dang Anh Thu, Ho Dang Trung Nghia, Pham Kieu Nguyet Oanh, Nguyen Hoan Phu, Vu Thi Ty Hang, Nguyen Van Vinh Chau, Nguyen Thuy Thuong Thuong, Le Van Tan, Guy E. Thwaites, Ronald B. Geskus
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Diagnosis of tuberculous meningitis (TBM) is hampered by the lack of a gold standard. Current microbiological tests lack sensitivity and clinical diagnostic approaches are subjective. We therefore built a diagnostic model that can
Externí odkaz:
https://doaj.org/article/37362129d3004cc6911f5d8f62d8354d
Autor:
Hao Chung The, Phuong Pham, Tuyen Ha Thanh, Linh Vo Kim Phuong, Nguyen Phuong Yen, Son-Nam H. Le, Duong Vu Thuy, Tran Thi Hong Chau, Hoang Le Phuc, Nguyen Minh Ngoc, Lu Lan Vi, Alison E. Mather, Guy E. Thwaites, Nicholas R. Thomson, Stephen Baker, Duy Thanh Pham
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Salmonella enterica serotype 1,4,[5],12:i:- (Typhimurium monophasic variant) of sequence type (ST) 34 has emerged as the predominant pandemic genotype in recent decades. Despite increasing reports of resistance to antimicrobials in Southeast
Externí odkaz:
https://doaj.org/article/6dbe49b9e4754120a267b2da7f5688de
Autor:
Hoang N. H. Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E. Thwaites, Lindsay J. Hall, Daniel J. Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of CRC, genomic s
Externí odkaz:
https://doaj.org/article/7a0c5b30b03f4264adee486f8019a654
Autor:
Dao Nguyen Vinh, Nguyen Thi Duy Nhat, Erwin de Bruin, Nguyen Ha Thao Vy, Tran Thi Nhu Thao, Huynh Thi Phuong, Pham Hong Anh, Stacy Todd, Tran Minh Quan, Nguyen Thi Le Thanh, Nguyen Thi Nam Lien, Nguyen Thi Hong Ha, Tran Thi Kim Hong, Pham Quang Thai, Marc Choisy, Tran Dang Nguyen, Cameron P. Simmons, Guy E. Thwaites, Hannah E. Clapham, Nguyen Van Vinh Chau, Marion Koopmans, Maciej F. Boni
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Multi-strain pathogens, such as influenza, present challenges for interpretation of seroprevalence data as estimates may vary by strain. Here, the authors develop a method for estimating age-specific seroprevalence based on principal components analy
Externí odkaz:
https://doaj.org/article/a68e51831ae9495fbcae680c69278194
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
TBM is the most severe form of tuberculosis. Clinical trial data are required to provide an evidence base for adjunctive dexamethasone in HIV-positive individuals with TBM, and to guide clinical practice. This document details the planned analyses at
Externí odkaz:
https://doaj.org/article/7b5d79d5dbbb44b3a37d96ca5135eff7
Autor:
Hao Chung The, Ladaporn Bodhidatta, Duy Thanh Pham, Carl J. Mason, Tuyen Ha Thanh, Phat Voong Vinh, Paul Turner, Sopheak Hem, David A. B. Dance, Paul N. Newton, Rattanaphone Phetsouvanh, Viengmon Davong, Guy E. Thwaites, Nicholas R. Thomson, Stephen Baker, Maia A. Rabaa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Hao Chung The et al. analyze 1,804 Shigella genome sequences from organisms isolated in four Southeast Asian countries over three decades to study the evolution of both S. flexneri and S. sonnei. This study suggests that adaptation to antimicrobial p
Externí odkaz:
https://doaj.org/article/c0586ea17c974f4dbfd83c1d9d6a76a4
Autor:
Le Hong Van, Phan Trieu Phu, Dao Nguyen Vinh, Vo Thanh Son, Nguyen Thi Hanh, Le Thanh Hoang Nhat, Nguyen Huu Lan, Truong Van Vinh, Nguyen Thi Mai Trang, Dang Thi Minh Ha, Guy E. Thwaites, Nguyen Thuy Thuong Thuong
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Multidrug resistant tuberculosis (MDR-TB) remains a serious public health problem with poor treatment outcomes. Predictors of poor outcomes vary in different regions. Vietnam is among the top 30 high burden of MDR-TB countries. We
Externí odkaz:
https://doaj.org/article/b4aae187361e41d181782848c43ed683
Autor:
Joseph Donovan, Trinh Dong Huu Khanh, Guy E. Thwaites, Ronald B. Geskus, ACT HIV investigators
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
TBM is the most severe form of tuberculosis. Clinical trial data are required to provide an evidence base for adjunctive dexamethasone in HIV-positive individuals with TBM, and to guide clinical practice. This document details the planned analyses at
Externí odkaz:
https://doaj.org/article/5e2ecc06a5a8473cba32bb3e6a9aa60a