Zobrazeno 1 - 10
of 573
pro vyhledávání: '"Guy E. Thwaites"'
Autor:
Liane S. Canas, Trinh H. K. Dong, Daniel Beasley, Joseph Donovan, Jon O. Cleary, Richard Brown, Nguyen Thuy Thuong Thuong, Phu Hoan Nguyen, Ha Thi Nguyen, Reza Razavi, Sebastien Ourselin, Guy E. Thwaites, Marc Modat, the Vietnam ICU Translational Applications Laboratory (VITAL) Investigators
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. Clinical features, such as coma, can predict death, but they are insufficient for the accurate prognosis of other outcomes, especially when impacted by co-morbidities such
Externí odkaz:
https://doaj.org/article/08a080fc43a44141b75690f09cfec498
Autor:
Hoang Thanh Hai, Le Thanh Hoang Nhat, Trinh Thi Bich Tram, Do Dinh Vinh, Artika P Nath, Joseph Donovan, Nguyen Thi Anh Thu, Dang Van Thanh, Nguyen Duc Bang, Dang Thi Minh Ha, Nguyen Hoan Phu, Ho Dang Trung Nghia, Le Hong Van, Michael Inouye, Guy E Thwaites, Nguyen Thuy Thuong Thuong
Publikováno v:
eLife, Vol 13 (2024)
Mortality and morbidity from tuberculous meningitis (TBM) are common, primarily due to inflammatory response to Mycobacterium tuberculosis infection, yet the underlying mechanisms remain poorly understood. We aimed to uncover genes and pathways assoc
Externí odkaz:
https://doaj.org/article/bc95681a731846ba918190c3d7e3cad9
Autor:
Srinivasan Vijay, Nguyen Le Hoai Bao, Dao Nguyen Vinh, Le Thanh Hoang Nhat, Do Dang Anh Thu, Nguyen Le Quang, Le Pham Tien Trieu, Hoang Ngoc Nhung, Vu Thi Ngoc Ha, Phan Vuong Khac Thai, Dang Thi Minh Ha, Nguyen Huu Lan, Maxine Caws, Guy E Thwaites, Babak Javid, Nguyen Thuy Thuong
Publikováno v:
eLife, Vol 13 (2024)
Antibiotic tolerance in Mycobacterium tuberculosis reduces bacterial killing, worsens treatment outcomes, and contributes to resistance. We studied rifampicin tolerance in isolates with or without isoniazid resistance (IR). Using a minimum duration o
Externí odkaz:
https://doaj.org/article/3b8a06ec8c904a9c82bb9d877cf08e28
Autor:
Ruan Spies, Hanh N. Hong, Phu P. Trieu, Luong K. Lan, Kim Lan, N.N. Hue, Nguyen T.L. Huong, Tran T.L.N. Thao, Nguyen L. Quang, Thu D.D. Anh, Truong V. Vinh, Dang T.M. Ha, Phan T. Dat, Nguyen P. Hai, Le H. Van, Guy E. Thwaites, Nguyen T.T. Thuong, James A. Watson, Timothy M. Walker
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 3, Pp 499-509 (2024)
We characterized the spatial distribution of drug-susceptible (DS) and multidrug-resistant (MDR) tuberculosis (TB) cases in Ho Chi Minh City, Vietnam, a major metropolis in southeastern Asia, and explored demographic and socioeconomic factors associa
Externí odkaz:
https://doaj.org/article/e118477f0ba44082be8d6d00985f8e70
Autor:
Trinh Huu Khanh Dong, Joseph Donovan, Nghiem My Ngoc, Do Dang Anh Thu, Ho Dang Trung Nghia, Pham Kieu Nguyet Oanh, Nguyen Hoan Phu, Vu Thi Ty Hang, Nguyen Van Vinh Chau, Nguyen Thuy Thuong Thuong, Le Van Tan, Guy E. Thwaites, Ronald B. Geskus
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Diagnosis of tuberculous meningitis (TBM) is hampered by the lack of a gold standard. Current microbiological tests lack sensitivity and clinical diagnostic approaches are subjective. We therefore built a diagnostic model that can
Externí odkaz:
https://doaj.org/article/37362129d3004cc6911f5d8f62d8354d
Autor:
Hao Chung The, Phuong Pham, Tuyen Ha Thanh, Linh Vo Kim Phuong, Nguyen Phuong Yen, Son-Nam H. Le, Duong Vu Thuy, Tran Thi Hong Chau, Hoang Le Phuc, Nguyen Minh Ngoc, Lu Lan Vi, Alison E. Mather, Guy E. Thwaites, Nicholas R. Thomson, Stephen Baker, Duy Thanh Pham
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Salmonella enterica serotype 1,4,[5],12:i:- (Typhimurium monophasic variant) of sequence type (ST) 34 has emerged as the predominant pandemic genotype in recent decades. Despite increasing reports of resistance to antimicrobials in Southeast
Externí odkaz:
https://doaj.org/article/6dbe49b9e4754120a267b2da7f5688de
Autor:
Duc Hong Du, Ronald B Geskus, Yanlin Zhao, Luigi Ruffo Codecasa, Daniela Maria Cirillo, Reinout van Crevel, Dyshelly Nurkartika Pascapurnama, Lidya Chaidir, Stefan Niemann, Roland Diel, Shaheed Vally Omar, Louis Grandjean, Sakib Rokadiya, Arturo Torres Ortitz, Nguyễn Hữu Lân, Đặng Thị Minh Hà, E Grace Smith, Esther Robinson, Martin Dedicoat, Le Thanh Hoang Nhat, Guy E Thwaites, Le Hong Van, Nguyen Thuy Thuong Thuong, Timothy M Walker
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 8, p e0003674 (2024)
[This corrects the article DOI: 10.1371/journal.pgph.0001788.].
Externí odkaz:
https://doaj.org/article/5c902d7712ed44d3a63852b7aabd25f3
Autor:
Hoang N. H. Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E. Thwaites, Lindsay J. Hall, Daniel J. Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of CRC, genomic s
Externí odkaz:
https://doaj.org/article/7a0c5b30b03f4264adee486f8019a654
Autor:
Nguyen Thi Hoang Mai, Nicholas Dobbs, Nguyen Hoan Phu, Romain A Colas, Le TP Thao, Nguyen TT Thuong, Ho DT Nghia, Nguyen HH Hanh, Nguyen T Hang, A Dorothee Heemskerk, Jeremy N Day, Lucy Ly, Do DA Thu, Laura Merson, Evelyne Kestelyn, Marcel Wolbers, Ronald Geskus, David Summers, Nguyen VV Chau, Jesmond Dalli, Guy E Thwaites
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/cd4e0a5cd9fb4497a8a9948b8fd56585
Autor:
Duc Hong Du, Ronald B Geskus, Yanlin Zhao, Luigi Ruffo Codecasa, Daniela Maria Cirillo, Reinout van Crevel, Dyshelly Nurkartika Pascapurnama, Lidya Chaidir, Stefan Niemann, Roland Diel, Shaheed Vally Omar, Louis Grandjean, Sakib Rokadiya, Arturo Torres Ortitz, Nguyễn Hữu Lân, Đặng Thị Minh Hà, E Grace Smith, Esther Robinson, Martin Dedicoat, Le Thanh Hoang Nhat, Guy E Thwaites, Le Hong Van, Nguyen Thuy Thuong Thuong, Timothy M Walker
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 12, p e0001788 (2023)
Six lineages of Mycobacterium tuberculosis sensu stricto (which excludes M. africanum) are described. Single-country or small observational data suggest differences in clinical phenotype between lineages. We present strain lineage and clinical phenot
Externí odkaz:
https://doaj.org/article/3e1033c2e23f45f384d8e5166dd225e4