Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Guy Casy"'
Autor:
Axtell, Alex T., Cobley, Christopher J., Klosin, Jerzy, Whiteker, Gregory T., Zanotti-Gerosa, Antonio, Abboud, Khalil A.
Publikováno v:
Angewandte Chemie. International Edition; September 2005, Vol. 44 Issue: 36 p5834-5838, 5p
Autor:
Alex T. Axtell, Christopher J. Cobley, Jerzy Klosin, Gregory T. Whiteker, Antonio Zanotti-Gerosa, Khalil A. Abboud
Publikováno v:
Angewandte Chemie International Edition; Sep2005, Vol. 44 Issue 36, p5834-5838, 5p
Autor:
Andrew J. Wildsmith, Mark J. Burk, Julian P. Henschke, Daniela Herzberg, Christopher J. Cobley, Justine A. Peterson, Christophe G. Malan, Guy Casy
Publikováno v:
Advanced Synthesis & Catalysis. 345:300-307
The novel biaryldiphosphine ligand 1 (Hexa- PHEMP) has been prepared in five steps from commercially available 3,4,5-trimethylphenol using a concise synthetic route. This approach also allows fine tuning of the ligand×s stereoelectronic properties t
Autor:
Nadine Derrien, Richard C. Lloyd, Raymond McCague, Mark E. B. Smith, Michael C. Lloyd, Guy Casy, Stephen Taylor, David A. Chaplin
Publikováno v:
Tetrahedron: Asymmetry. 12:703-705
A route to all eight stereoisomers of 3-( tert -butoxycarbonylamino)-4-hydroxycyclopentanecarboxylic acid methyl ester is presented; these products should prove to be valuable scaffolds in pharmaceutical discovery.
Publikováno v:
ChemInform. 23
A genetically engineered version of Bacillus stearothermophilus lactate dehydrogenase, incorporating structural motifs which serve to alter substrate specificity in favour of α-keto acids with bulky aliphatic side chains, was used to effect enantios
Autor:
Guy Casy
Publikováno v:
ChemInform. 24
The enantioselective reduction 2,4-dioxo acids catalysed by lactate dehydrogenases provided access to 2-hydroxy-4-oxo acids of both S and R configuration. Subsequent diastereoselective chemical reduction affords 4-substituted 2-hydroxybutyrolactones.
Publikováno v:
ChemInform. 25
Publikováno v:
ChemInform. 30
Autor:
Guy Casy
Publikováno v:
Tetrahedron Letters. 33:8159-8162
The enantioselective reduction 2,4-dioxo acids catalysed by lactate dehydrogenases provided access to 2-hydroxy-4-oxo acids of both S and R configuration. Subsequent diastereoselective chemical reduction affords 4-substituted 2-hydroxybutyrolactones.
Publikováno v:
Tetrahedron Letters. 33:817-820
The enantioselective reduction of α-keto acids, catalysed by lactate dehydrogenase, has been extended bo β,χ-unsaturated substrates, providing functionalised allylic alcohols in high optical purity.