Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Guy C. M. Steffens"'
Autor:
Melanie Hemmrich, Lena Katharina Eckert, Guy C. M. Steffens, Norbert Pallua, Gerrit Grieb, David Simons, Jürgen Bernhagen
Publikováno v:
Wound Repair and Regeneration. 20:707-714
Macrophage migration inhibitory factor (MIF), a structurally and functionally unique pleiotropic mediator in inflammation and immune processes, was identified decades ago. There is now strong evidence that MIF promotes revascularization and is involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b7fa127a2bee5abb84f3f1bf1567abb
https://doi.org/10.1111/j.1524-475x.2012.00817.x
https://doi.org/10.1111/j.1524-475x.2012.00817.x
Autor:
Gerrit Grieb, Jürgen Bernhagen, Guy C. M. Steffens, David Simons, Norbert Pallua, Andrzej Piatkowski
Publikováno v:
Burns. 36:335-342
Serum macrophage migration inhibitory factor (MIF) and procalcitonin (PCT) concentrations as well as leucocyte numbers were evaluated in a retrospective study with 23 patients with severe burn injuries. The MIF and PCT concentrations as well as the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8627b3d9428a361677f8336858675e79
https://doi.org/10.1016/j.burns.2009.04.019
https://doi.org/10.1016/j.burns.2009.04.019
Publikováno v:
Cells Tissues Organs. 191:96-104
The use of implantable biomaterials, such as artificial skin substitutes used for dermal defects, remains limited by the low angiogenic potential of these products. The rapid in vivo degradation of growth factors contributes to the limiting of angiog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7532d4a982f343cf23dd307e9dd5565a
https://doi.org/10.1159/000231473
https://doi.org/10.1159/000231473
Autor:
Christian Herren, Hans-Josef Erli, Guy C. M. Steffens, B. Hermanns-Sachweh, Matthias Rüger, M. von Walter, Tobias Johannes Gensior, Willi Jahnen-Dechent
Publikováno v:
Acta Biomaterialia. 4:997-1004
The porous TiO2/glass composite Ecopore has potential applications in hard tissue replacement. We describe the modification of Ecopore with the growth factor bone morphogenetic protein-2 (BMP-2) to add osteoinductive properties. Ecopore covalently co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e91fd8fe3797b6a549ff5a58865e33f
https://doi.org/10.1016/j.actbio.2008.01.020
https://doi.org/10.1016/j.actbio.2008.01.020
Publikováno v:
Biomaterials. 29:66-74
The poor vascularization rate of matrices following cell invasion is considered to be one of the main shortcomings of scaffolds used in tissue engineering. In the past decade much effort has been directed towards enhancing the angiogenic potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0021c44d8b69684c9b25337685c7d1fc
https://doi.org/10.1016/j.biomaterials.2007.08.049
https://doi.org/10.1016/j.biomaterials.2007.08.049
Autor:
Christian Weber, Guy C. M. Steffens, Regina M. Krohn, Jens M. Baron, Manfred Dewor, Jürgen Bernhagen
Publikováno v:
FEBS Letters. 581:4734-4742
MIF was recently redefined as an inflammatory cytokine, which functions as a critical mediator of diseases such as septic shock, rheumatoid arthritis, atherosclerosis, and cancer. MIF also regulates wound healing processes. Given that fibroblast migr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141fb63973fbd34679b4d265a7bfd4b1
https://doi.org/10.1016/j.febslet.2007.08.071
https://doi.org/10.1016/j.febslet.2007.08.071
Publikováno v:
The International Journal of Artificial Organs. 29:1167-1173
Ongoing research has achieved much progress towards the development of new artificial skin substitute products. However, effective implant material for correcting full-thickness defects (such as those arising from extensive burns, tumor resection, he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50703c4679da366bca1ac62cdd6db1a5
https://doi.org/10.1177/039139880602901210
https://doi.org/10.1177/039139880602901210
Publikováno v:
Journal of Materials Science: Materials in Medicine. 17:735-741
Since the survival of ingrowing cells in biomaterials for regenerative processes largely depends on the supply of nutrients and oxygen, angiogenesis plays an important role in the development of new materials for tissue engineering. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddc0d4ee65479d052351156b119d048
https://doi.org/10.1007/s10856-006-9684-x
https://doi.org/10.1007/s10856-006-9684-x
Autor:
P. Prével, C. Yao, Guy C. M. Steffens, Ernst Magnus Noah, Norbert Pallua, Marta Markowicz, P. Schenck
Publikováno v:
Tissue Engineering. 10:1502-1509
One of the prominent shortcomings of matrices for tissue engineering is their poor ability to support angiogenesis. We report here on experiments to enhance the angiogenic properties of collagen matrices. Our aim is to achieve this goal by covalently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf0608488ea9c752e1b12dd3d0db3a2
https://doi.org/10.1089/ten.2004.10.1502
https://doi.org/10.1089/ten.2004.10.1502
Publikováno v:
Materialwissenschaft und Werkstofftechnik. 34:1058-1063
A novel technique is used to produce an open porous titanium dioxide/glass composite, named Ecopore, with promising structural and biological properties for the development as a bone graft. This study aims at a fast and lasting integration of the new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::601dbef3d5ba89d1de44c1841ed7f3c4
https://doi.org/10.1002/mawe.200300706
https://doi.org/10.1002/mawe.200300706